vinpocetine-7213 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the vinpocetine-7213 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
AK2 adenylate kinase 2
AMH anti-Mullerian hormone
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
AQP3 aquaporin 3 (Gill blood group)
ARHGAP35 Rho GTPase activating protein 35
ARSD arylsulfatase D
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BCAP29 B-cell receptor-associated protein 29
BTN2A2 butyrophilin, subfamily 2, member A2
C9ORF9 chromosome 9 open reading frame 9
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CACNG5 calcium channel, voltage-dependent, gamma subunit 5
CCL8 chemokine (C-C motif) ligand 8
CD53 CD53 molecule
CD58 CD58 molecule
CDKN2A cyclin-dependent kinase inhibitor 2A
CHRM3 cholinergic receptor, muscarinic 3
COL14A1 collagen, type XIV, alpha 1
CPED1 cadherin-like and PC-esterase domain containing 1
CRTC1 CREB regulated transcription coactivator 1
CSHL1 chorionic somatomammotropin hormone-like 1
CST4 cystatin S
DLX2 distal-less homeobox 2
DOK2 docking protein 2, 56kDa
EGFL7 EGF-like-domain, multiple 7
EML2 echinoderm microtubule associated protein like 2
EML3 echinoderm microtubule associated protein like 3
ETV5 ets variant 5
EXOSC1 exosome component 1
FAM155A family with sequence similarity 155, member A
FAM214B family with sequence similarity 214, member B
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GLRA1 glycine receptor, alpha 1
HDGFRP3 hepatoma-derived growth factor, related protein 3
HEG1 heart development protein with EGF-like domains 1
HNF4A hepatocyte nuclear factor 4, alpha
HP haptoglobin
HR hair growth associated
HSPB3 heat shock 27kDa protein 3
IFNA16 interferon, alpha 16
IFT122 intraflagellar transport 122
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KIAA1109 KIAA1109
KLRD1 killer cell lectin-like receptor subfamily D, member 1
LGALS9 lectin, galactoside-binding, soluble, 9
LIG4 ligase IV, DNA, ATP-dependent
LIMK1 LIM domain kinase 1
LLGL1 lethal giant larvae homolog 1 (Drosophila)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAGEA5 melanoma antigen family A5
MARK4 MAP/microtubule affinity-regulating kinase 4
MASP2 mannan-binding lectin serine peptidase 2
MFAP5 microfibrillar associated protein 5
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
NCAM1 neural cell adhesion molecule 1
NEK9 NIMA-related kinase 9
NFX1 nuclear transcription factor, X-box binding 1
NKTR natural killer cell triggering receptor
NOD1 nucleotide-binding oligomerization domain containing 1
PARD6B par-6 family cell polarity regulator beta
PBOV1 prostate and breast cancer overexpressed 1
PCDHA9 protocadherin alpha 9
PEX5 peroxisomal biogenesis factor 5
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLA2G1B phospholipase A2, group IB (pancreas)
PPP1R3A protein phosphatase 1, regulatory subunit 3A
PTCH2 patched 2
PTPN7 protein tyrosine phosphatase, non-receptor type 7
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RGS12 regulator of G-protein signaling 12
RUNDC3A RUN domain containing 3A
SAP30 Sin3A-associated protein, 30kDa
SDC3 syndecan 3
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SH3GL3 SH3-domain GRB2-like 3
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SMAD5 SMAD family member 5
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SOCS3 suppressor of cytokine signaling 3
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
STIM1 stromal interaction molecule 1
TAPBP TAP binding protein (tapasin)
TCP11L1 t-complex 11, testis-specific-like 1
THOC5 THO complex 5
TIMELESS timeless circadian clock
TMEM63A transmembrane protein 63A
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF385D zinc finger protein 385D
ZNF407 zinc finger protein 407
ZNF516 zinc finger protein 516
ZNF821 zinc finger protein 821

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
AHR aryl hydrocarbon receptor
C16ORF45 chromosome 16 open reading frame 45
C1ORF109 chromosome 1 open reading frame 109
C1ORF159 chromosome 1 open reading frame 159
C7ORF43 chromosome 7 open reading frame 43
CENPT centromere protein T
CIR1 corepressor interacting with RBPJ, 1
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CTNNBIP1 catenin, beta interacting protein 1
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DCAF17 DDB1 and CUL4 associated factor 17
DTWD1 DTW domain containing 1
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
EGLN3 egl-9 family hypoxia-inducible factor 3
ELOVL4 ELOVL fatty acid elongase 4
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ETAA1 Ewing tumor-associated antigen 1
FAM188A family with sequence similarity 188, member A
FGGY FGGY carbohydrate kinase domain containing
FZD4 frizzled class receptor 4
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GCA grancalcin, EF-hand calcium binding protein
GSTT1 glutathione S-transferase theta 1
HS1BP3 HCLS1 binding protein 3
IL4R interleukin 4 receptor
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IREB2 iron-responsive element binding protein 2
KAT2A K(lysine) acetyltransferase 2A
KIZ kizuna centrosomal protein
KLHL26 kelch-like family member 26
KPTN kaptin (actin binding protein)
LIN7B lin-7 homolog B (C. elegans)
LRP3 low density lipoprotein receptor-related protein 3
LRRC20 leucine rich repeat containing 20
LZTFL1 leucine zipper transcription factor-like 1
MAGEH1 melanoma antigen family H1
MAST3 microtubule associated serine/threonine kinase 3
MEIS1 Meis homeobox 1
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMP9 matrix metallopeptidase 9
MON1B MON1 secretory trafficking family member B
MORC3 MORC family CW-type zinc finger 3
MRPL52 mitochondrial ribosomal protein L52
MXD3 MAX dimerization protein 3
NME6 NME/NM23 nucleoside diphosphate kinase 6
NRSN2 neurensin 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PCBP4 poly(rC) binding protein 4
PGP phosphoglycolate phosphatase
PILRB paired immunoglobin-like type 2 receptor beta
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLD2 phospholipase D2
PNPLA6 patatin-like phospholipase domain containing 6
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
PP14571 uncharacterized LOC100130449
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PYCRL pyrroline-5-carboxylate reductase-like
RBL1 retinoblastoma-like 1
RGS19 regulator of G-protein signaling 19
RIPK4 receptor-interacting serine-threonine kinase 4
RNF31 ring finger protein 31
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SGK1 serum/glucocorticoid regulated kinase 1
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SOX3 SRY (sex determining region Y)-box 3
SPINK4 serine peptidase inhibitor, Kazal type 4
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TEP1 telomerase-associated protein 1
TESK2 testis-specific kinase 2
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TK1 thymidine kinase 1, soluble
TLN1 talin 1
TM7SF3 transmembrane 7 superfamily member 3
TMEM115 transmembrane protein 115
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRAF2 TNF receptor-associated factor 2
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TTC23 tetratricopeptide repeat domain 23
UFSP2 UFM1-specific peptidase 2
ULBP2 UL16 binding protein 2
ZFP69B ZFP69 zinc finger protein B
ZNF189 zinc finger protein 189
ZNF211 zinc finger protein 211
ZNF226 zinc finger protein 226
ZNF250 zinc finger protein 250
ZNF268 zinc finger protein 268
ZNF492 zinc finger protein 492
ZNF574 zinc finger protein 574
ZNF8 zinc finger protein 8