vinblastine-7556 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the vinblastine-7556 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADARB1 adenosine deaminase, RNA-specific, B1
AKAP12 A kinase (PRKA) anchor protein 12
AMOTL2 angiomotin like 2
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARHGAP19 Rho GTPase activating protein 19
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
BEX1 brain expressed, X-linked 1
BIN1 bridging integrator 1
BNC2 basonuclin 2
BRAP BRCA1 associated protein
C19ORF66 chromosome 19 open reading frame 66
C1ORF35 chromosome 1 open reading frame 35
C9ORF114 chromosome 9 open reading frame 114
CALD1 caldesmon 1
CCNT1 cyclin T1
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CEP290 centrosomal protein 290kDa
CLASP2 cytoplasmic linker associated protein 2
CLIP4 CAP-GLY domain containing linker protein family, member 4
COBL cordon-bleu WH2 repeat protein
CTGF connective tissue growth factor
CYR61 cysteine-rich, angiogenic inducer, 61
DENND5B DENN/MADD domain containing 5B
DUSP1 dual specificity phosphatase 1
EIF4E2 eukaryotic translation initiation factor 4E family member 2
EML3 echinoderm microtubule associated protein like 3
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ETNK2 ethanolamine kinase 2
FAM69A family with sequence similarity 69, member A
FBXO2 F-box protein 2
FGF1 fibroblast growth factor 1 (acidic)
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GOSR2 golgi SNAP receptor complex member 2
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa
HBEGF heparin-binding EGF-like growth factor
HEG1 heart development protein with EGF-like domains 1
HNF1B HNF1 homeobox B
HOOK1 hook microtubule-tethering protein 1
IFI35 interferon-induced protein 35
IFI6 interferon, alpha-inducible protein 6
IL6ST interleukin 6 signal transducer
IL7R interleukin 7 receptor
KAT5 K(lysine) acetyltransferase 5
KIF5C kinesin family member 5C
KISS1 KiSS-1 metastasis-suppressor
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KRT34 keratin 34, type I
LIG1 ligase I, DNA, ATP-dependent
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAPK11 mitogen-activated protein kinase 11
MAST3 microtubule associated serine/threonine kinase 3
MECP2 methyl CpG binding protein 2
METTL2B methyltransferase like 2B
MKL1 megakaryoblastic leukemia (translocation) 1
MON1B MON1 secretory trafficking family member B
MVK mevalonate kinase
NBAS neuroblastoma amplified sequence
NEK3 NIMA-related kinase 3
NUMB numb homolog (Drosophila)
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PDE4A phosphodiesterase 4A, cAMP-specific
PHKG2 phosphorylase kinase, gamma 2 (testis)
PRDM2 PR domain containing 2, with ZNF domain
RPP25 ribonuclease P/MRP 25kDa subunit
SAMD4A sterile alpha motif domain containing 4A
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SETD4 SET domain containing 4
SGSM3 small G protein signaling modulator 3
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SMC4 structural maintenance of chromosomes 4
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SOWAHC sosondowah ankyrin repeat domain family member C
SRPK2 SRSF protein kinase 2
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
STX5 syntaxin 5
TAZ tafazzin
TEAD3 TEA domain family member 3
TGFB2 transforming growth factor, beta 2
TLE3 transducin-like enhancer of split 3
TMEM47 transmembrane protein 47
TMPO thymopoietin
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNK1 tyrosine kinase, non-receptor, 1
TOX thymocyte selection-associated high mobility group box
TPI1 triosephosphate isomerase 1
TRIM58 tripartite motif containing 58
UBE3A ubiquitin protein ligase E3A
UGCG UDP-glucose ceramide glucosyltransferase
XYLT2 xylosyltransferase II
YLPM1 YLP motif containing 1
ZNF202 zinc finger protein 202
ZNF267 zinc finger protein 267
ZNF292 zinc finger protein 292
ZNF574 zinc finger protein 574

decreased expression

Symbol Name
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
AUH AU RNA binding protein/enoyl-CoA hydratase
C12ORF4 chromosome 12 open reading frame 4
CBS cystathionine-beta-synthase
CCDC176 coiled-coil domain containing 176
CD53 CD53 molecule
CDADC1 cytidine and dCMP deaminase domain containing 1
CDHR2 cadherin-related family member 2
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDT1 chromatin licensing and DNA replication factor 1
CEP85 centrosomal protein 85kDa
CFAP69 cilia and flagella associated protein 69
CHML choroideremia-like (Rab escort protein 2)
CHST10 carbohydrate sulfotransferase 10
CINP cyclin-dependent kinase 2 interacting protein
CLCN6 chloride channel, voltage-sensitive 6
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CPVL carboxypeptidase, vitellogenic-like
DDN dendrin
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13
DPY19L2P2 DPY19L2 pseudogene 2
EDIL3 EGF-like repeats and discoidin I-like domains 3
EFNA3 ephrin-A3
ELOVL4 ELOVL fatty acid elongase 4
EN1 engrailed homeobox 1
ERN2 endoplasmic reticulum to nucleus signaling 2
EXOSC1 exosome component 1
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM222B family with sequence similarity 222, member B
FBXL15 F-box and leucine-rich repeat protein 15
FPGT fucose-1-phosphate guanylyltransferase
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GID4 GID complex subunit 4
GLDC glycine dehydrogenase (decarboxylating)
GLS2 glutaminase 2 (liver, mitochondrial)
GLT8D2 glycosyltransferase 8 domain containing 2
GMIP GEM interacting protein
GPATCH2L G patch domain containing 2-like
HAS2 hyaluronan synthase 2
HIST1H2AG histone cluster 1, H2ag
HIST1H3H histone cluster 1, H3h
HOXC4 homeobox C4
IL17RB interleukin 17 receptor B
IRAK4 interleukin-1 receptor-associated kinase 4
KRT4 keratin 4, type II
LHFP lipoma HMGIC fusion partner
LOC730101 uncharacterized LOC730101
LYPD1 LY6/PLAUR domain containing 1
MAN2C1 mannosidase, alpha, class 2C, member 1
MAPK12 mitogen-activated protein kinase 12
MCM9 minichromosome maintenance complex component 9
NARFL nuclear prelamin A recognition factor-like
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PSAT1 phosphoserine aminotransferase 1
PTTG3P pituitary tumor-transforming 3, pseudogene
RARS arginyl-tRNA synthetase
RHOBTB1 Rho-related BTB domain containing 1
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIN1 Ras and Rab interactor 1
RNF121 ring finger protein 121
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNF31 ring finger protein 31
RNF39 ring finger protein 39
SCIN scinderin
SCYL2 SCY1-like 2 (S. cerevisiae)
SDC3 syndecan 3
SEC14L2 SEC14-like 2 (S. cerevisiae)
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
STAC SH3 and cysteine rich domain
TAGLN3 transgelin 3
TENM4 teneurin transmembrane protein 4
TRAIP TRAF interacting protein
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TSPAN12 tetraspanin 12
TUBA1A tubulin, alpha 1a
TUBA1B tubulin, alpha 1b
TUBA1C tubulin, alpha 1c
TUBA3C tubulin, alpha 3c
TUBA3D tubulin, alpha 3d
TUBA4A tubulin, alpha 4a
TUBB tubulin, beta class I
TUBB2A tubulin, beta 2A class IIa
TUBB3 tubulin, beta 3 class III
TUBB4B tubulin, beta 4B class IVb
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBXN2B UBX domain protein 2B
ULBP2 UL16 binding protein 2
USB1 U6 snRNA biogenesis 1
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZNF552 zinc finger protein 552