vinblastine-7517 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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194 genes differentially expressed following the vinblastine-7517 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ABR active BCR-related
ACTR5 ARP5 actin-related protein 5 homolog (yeast)
ADAP2 ArfGAP with dual PH domains 2
ADARB1 adenosine deaminase, RNA-specific, B1
AK2 adenylate kinase 2
AKR1C1 aldo-keto reductase family 1, member C1
APOL2 apolipoprotein L, 2
AQP3 aquaporin 3 (Gill blood group)
BBS9 Bardet-Biedl syndrome 9
C3 complement component 3
CALD1 caldesmon 1
CCDC85C coiled-coil domain containing 85C
CFLAR CASP8 and FADD-like apoptosis regulator
CHST10 carbohydrate sulfotransferase 10
CLDN11 claudin 11
CSHL1 chorionic somatomammotropin hormone-like 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTSV cathepsin V
CYB561 cytochrome b561
DDX49 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DMWD dystrophia myotonica, WD repeat containing
DPY19L1P1 DPY19L1 pseudogene 1
ENO1 enolase 1, (alpha)
ENOX2 ecto-NOX disulfide-thiol exchanger 2
EPHA2 EPH receptor A2
ERN2 endoplasmic reticulum to nucleus signaling 2
EXPH5 exophilin 5
FSCN1 fascin actin-bundling protein 1
FZD3 frizzled class receptor 3
GPR1 G protein-coupled receptor 1
GTPBP2 GTP binding protein 2
HIP1 huntingtin interacting protein 1
HIST1H2BO histone cluster 1, H2bo
HLA-G major histocompatibility complex, class I, G
HLA-J major histocompatibility complex, class I, J (pseudogene)
HNMT histamine N-methyltransferase
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HRASLS2 HRAS-like suppressor 2
IFI35 interferon-induced protein 35
INO80B INO80 complex subunit B
ISG20 interferon stimulated exonuclease gene 20kDa
JMJD4 jumonji domain containing 4
KANK1 KN motif and ankyrin repeat domains 1
KIAA0754 KIAA0754
KLF9 Kruppel-like factor 9
KRT13 keratin 13, type I
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LPAR2 lysophosphatidic acid receptor 2
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MED9 mediator complex subunit 9
MEF2A myocyte enhancer factor 2A
MINK1 misshapen-like kinase 1
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MRPL44 mitochondrial ribosomal protein L44
MST1R macrophage stimulating 1 receptor
MTA1 metastasis associated 1
MYO1B myosin IB
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NLRX1 NLR family member X1
PALM paralemmin
PCGF3 polycomb group ring finger 3
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
POLR2J4 polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene
PPP5C protein phosphatase 5, catalytic subunit
PRY PTPN13-like, Y-linked
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PTPRE protein tyrosine phosphatase, receptor type, E
PXDC1 PX domain containing 1
R3HCC1L R3H domain and coiled-coil containing 1-like
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RARS arginyl-tRNA synthetase
RASAL2 RAS protein activator like 2
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RGS2 regulator of G-protein signaling 2
RRP1B ribosomal RNA processing 1B
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SLC48A1 solute carrier family 48 (heme transporter), member 1
STK24 serine/threonine kinase 24
STX6 syntaxin 6
TBL1X transducin (beta)-like 1X-linked
TICAM1 toll-like receptor adaptor molecule 1
TJAP1 tight junction associated protein 1 (peripheral)
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TRIM15 tripartite motif containing 15
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TSC22D2 TSC22 domain family, member 2
TTLL5 tubulin tyrosine ligase-like family member 5
U2AF2 U2 small nuclear RNA auxiliary factor 2
WNK1 WNK lysine deficient protein kinase 1
YY1 YY1 transcription factor
ZNF710 zinc finger protein 710
ZNF771 zinc finger protein 771
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ANG angiogenin, ribonuclease, RNase A family, 5
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGAP5 Rho GTPase activating protein 5
ATAT1 alpha tubulin acetyltransferase 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BAGE B melanoma antigen
BEGAIN brain-enriched guanylate kinase-associated
C1ORF56 chromosome 1 open reading frame 56
C22ORF29 chromosome 22 open reading frame 29
C5AR1 complement component 5a receptor 1
CASD1 CAS1 domain containing 1
CCDC186 coiled-coil domain containing 186
CCP110 centriolar coiled coil protein 110kDa
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD82 CD82 molecule
CLDND1 claudin domain containing 1
COPZ2 coatomer protein complex, subunit zeta 2
CORT cortistatin
CST4 cystatin S
DAAM2 dishevelled associated activator of morphogenesis 2
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DMBT1 deleted in malignant brain tumors 1
DUSP2 dual specificity phosphatase 2
FADS2 fatty acid desaturase 2
FAM120C family with sequence similarity 120C
FAP fibroblast activation protein, alpha
FGD1 FYVE, RhoGEF and PH domain containing 1
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR68 G protein-coupled receptor 68
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HIST1H1B histone cluster 1, H1b
HIST1H2AE histone cluster 1, H2ae
HIST1H4C histone cluster 1, H4c
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
KAT2B K(lysine) acetyltransferase 2B
KLK8 kallikrein-related peptidase 8
KRT15 keratin 15, type I
LAMP5 lysosomal-associated membrane protein family, member 5
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LINC00115 long intergenic non-protein coding RNA 115
LINS lines homolog (Drosophila)
LMO2 LIM domain only 2 (rhombotin-like 1)
LNPEP leucyl/cystinyl aminopeptidase
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LOC257152 uncharacterized LOC257152
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LTC4S leukotriene C4 synthase
MAP9 microtubule-associated protein 9
MNS1 meiosis-specific nuclear structural 1
MT3 metallothionein 3
MXD3 MAX dimerization protein 3
OCA2 oculocutaneous albinism II
OPLAH 5-oxoprolinase (ATP-hydrolysing)
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PADI1 peptidyl arginine deiminase, type I
PER3 period circadian clock 3
PEX13 peroxisomal biogenesis factor 13
PKD2L1 polycystic kidney disease 2-like 1
PRLH prolactin releasing hormone
PROS1 protein S (alpha)
PTTG3P pituitary tumor-transforming 3, pseudogene
RAB3A RAB3A, member RAS oncogene family
RIPK4 receptor-interacting serine-threonine kinase 4
RLN2 relaxin 2
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RPAP2 RNA polymerase II associated protein 2
RUSC2 RUN and SH3 domain containing 2
SAA4 serum amyloid A4, constitutive
SCYL2 SCY1-like 2 (S. cerevisiae)
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SMA4 glucuronidase, beta pseudogene
SNHG20 small nucleolar RNA host gene 20
SNX15 sorting nexin 15
SREK1IP1 SREK1-interacting protein 1
SSPN sarcospan
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TBC1D2 TBC1 domain family, member 2
TCP10 t-complex 10
TMEM121 transmembrane protein 121
TMEM209 transmembrane protein 209
TMEM38B transmembrane protein 38B
TPSG1 tryptase gamma 1
TRAPPC2 trafficking protein particle complex 2
TWF2 twinfilin actin binding protein 2
VASH2 vasohibin 2
VGF VGF nerve growth factor inducible
XK X-linked Kx blood group
ZKSCAN4 zinc finger with KRAB and SCAN domains 4
ZNF250 zinc finger protein 250
ZNF254 zinc finger protein 254
ZNF586 zinc finger protein 586