vidarabine-2706 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the vidarabine-2706 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ACACB acetyl-CoA carboxylase beta
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
ADCK2 aarF domain containing kinase 2
AK1 adenylate kinase 1
ALDOB aldolase B, fructose-bisphosphate
AURKA aurora kinase A
C10ORF10 chromosome 10 open reading frame 10
C14ORF105 chromosome 14 open reading frame 105
C1ORF68 chromosome 1 open reading frame 68
C7ORF26 chromosome 7 open reading frame 26
CCL22 chemokine (C-C motif) ligand 22
CD6 CD6 molecule
CNGB3 cyclic nucleotide gated channel beta 3
COL14A1 collagen, type XIV, alpha 1
COL8A2 collagen, type VIII, alpha 2
CREB3L1 cAMP responsive element binding protein 3-like 1
CYB561 cytochrome b561
DBP D site of albumin promoter (albumin D-box) binding protein
DOCK9 dedicator of cytokinesis 9
DPP4 dipeptidyl-peptidase 4
DRD2 dopamine receptor D2
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
EDNRA endothelin receptor type A
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EXTL3 exostosin-like glycosyltransferase 3
FCAR Fc fragment of IgA receptor
FGF6 fibroblast growth factor 6
G0S2 G0/G1 switch 2
GABARAPL3 GABA(A) receptors associated protein like 3, pseudogene
GLRB glycine receptor, beta
GNAS GNAS complex locus
GPR3 G protein-coupled receptor 3
GUK1 guanylate kinase 1
HAP1 huntingtin-associated protein 1
HAPLN1 hyaluronan and proteoglycan link protein 1
HIST1H2AJ histone cluster 1, H2aj
HOXA1 homeobox A1
HYAL1 hyaluronoglucosaminidase 1
IBSP integrin-binding sialoprotein
IL1A interleukin 1, alpha
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IL24 interleukin 24
ING2 inhibitor of growth family, member 2
INSR insulin receptor
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KRT31 keratin 31, type I
KRT8P12 keratin 8 pseudogene 12
KSR1 kinase suppressor of ras 1
L1TD1 LINE-1 type transposase domain containing 1
LRRC23 leucine rich repeat containing 23
MAN1A2 mannosidase, alpha, class 1A, member 2
MARC1 mitochondrial amidoxime reducing component 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUC1 mucin 1, cell surface associated
MYO7A myosin VIIA
NPY4R neuropeptide Y receptor Y4
NRG1 neuregulin 1
NXPE4 neurexophilin and PC-esterase domain family, member 4
P2RY11 purinergic receptor P2Y, G-protein coupled, 11
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PCLO piccolo presynaptic cytomatrix protein
PNPLA3 patatin-like phospholipase domain containing 3
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RAPSN receptor-associated protein of the synapse
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RGS12 regulator of G-protein signaling 12
RPH3A rabphilin 3A
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SIPA1L1 signal-induced proliferation-associated 1 like 1
SIX3 SIX homeobox 3
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLMO1 slowmo homolog 1 (Drosophila)
SMC1A structural maintenance of chromosomes 1A
SNX1 sorting nexin 1
SOCS3 suppressor of cytokine signaling 3
SSX1 synovial sarcoma, X breakpoint 1
SYNDIG1 synapse differentiation inducing 1
SYTL2 synaptotagmin-like 2
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TGFB1 transforming growth factor, beta 1
TLR4 toll-like receptor 4
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TTC38 tetratricopeptide repeat domain 38
USP27X ubiquitin specific peptidase 27, X-linked
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VPS13B vacuolar protein sorting 13 homolog B (yeast)
WWP2 WW domain containing E3 ubiquitin protein ligase 2
ZBTB17 zinc finger and BTB domain containing 17

decreased expression

Symbol Name
ADGRE3 adhesion G protein-coupled receptor E3
ARMCX4 armadillo repeat containing, X-linked 4
ATG9A autophagy related 9A
C17ORF80 chromosome 17 open reading frame 80
C1ORF159 chromosome 1 open reading frame 159
C8ORF44 chromosome 8 open reading frame 44
CAMKMT calmodulin-lysine N-methyltransferase
CASS4 Cas scaffolding protein family member 4
CCDC85C coiled-coil domain containing 85C
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD68 CD68 molecule
CDC20 cell division cycle 20
CENPE centromere protein E, 312kDa
CFAP45 cilia and flagella associated protein 45
CFP complement factor properdin
COL9A2 collagen, type IX, alpha 2
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CTAGE9 CTAGE family, member 9
CTNNBIP1 catenin, beta interacting protein 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DCAF13 DDB1 and CUL4 associated factor 13
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
ECI2 enoyl-CoA delta isomerase 2
EFNA3 ephrin-A3
EFNA4 ephrin-A4
EHD3 EH-domain containing 3
EPHB6 EPH receptor B6
ERCC6 excision repair cross-complementation group 6
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM120C family with sequence similarity 120C
FBRS fibrosin
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FGL1 fibrinogen-like 1
GALK1 galactokinase 1
GK3P glycerol kinase 3 pseudogene
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPC3 glypican 3
GPR20 G protein-coupled receptor 20
HDAC7 histone deacetylase 7
HIST1H1E histone cluster 1, H1e
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL2 interleukin 2
INCENP inner centromere protein antigens 135/155kDa
IPP intracisternal A particle-promoted polypeptide
IRS1 insulin receptor substrate 1
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
LGALS4 lectin, galactoside-binding, soluble, 4
LOC257152 uncharacterized LOC257152
MAGEF1 melanoma antigen family F1
MEP1B meprin A, beta
MRPL44 mitochondrial ribosomal protein L44
MYL5 myosin, light chain 5, regulatory
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NINJ2 ninjurin 2
NOL10 nucleolar protein 10
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OVGP1 oviductal glycoprotein 1, 120kDa
PADI2 peptidyl arginine deiminase, type II
PCDH12 protocadherin 12
PCDHGB5 protocadherin gamma subfamily B, 5
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PIR pirin (iron-binding nuclear protein)
PLD3 phospholipase D family, member 3
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLK1 polo-like kinase 1
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
RAP1GAP2 RAP1 GTPase activating protein 2
REC8 REC8 meiotic recombination protein
REM1 RAS (RAD and GEM)-like GTP-binding 1
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RIBC2 RIB43A domain with coiled-coils 2
RPL10L ribosomal protein L10-like
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
S1PR4 sphingosine-1-phosphate receptor 4
SCG5 secretogranin V
SCML2 sex comb on midleg-like 2 (Drosophila)
SETD1A SET domain containing 1A
SH2D4A SH2 domain containing 4A
SLC12A8 solute carrier family 12, member 8
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SPAG4 sperm associated antigen 4
SRPX sushi-repeat containing protein, X-linked
STARD3 StAR-related lipid transfer (START) domain containing 3
STEAP1 six transmembrane epithelial antigen of the prostate 1
TEAD3 TEA domain family member 3
TESK1 testis-specific kinase 1
TPM3 tropomyosin 3
TSPAN13 tetraspanin 13
TTLL1 tubulin tyrosine ligase-like family member 1
UPB1 ureidopropionase, beta
UPP1 uridine phosphorylase 1
YPEL1 yippee-like 1 (Drosophila)
ZNF254 zinc finger protein 254
ZNF408 zinc finger protein 408
ZNF492 zinc finger protein 492
ZNF76 zinc finger protein 76