vascular skin disease Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Similar Terms
Downloads & Tools

Genes

363 genes co-occuring with the disease vascular skin disease in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 2.9387
KNG1 kininogen 1 2.35666
ACE angiotensin I converting enzyme 2.16289
C1S complement component 1, s subcomponent 2.06036
CA8 carbonic anhydrase VIII 2.03471
ACVRL1 activin A receptor type II-like 1 1.9094
F12 coagulation factor XII (Hageman factor) 1.90754
KLKB1 kallikrein B, plasma (Fletcher factor) 1 1.89592
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 1.82052
ITPKC inositol-trisphosphate 3-kinase C 1.73277
HRH1 histamine receptor H1 1.6597
CRP C-reactive protein, pentraxin-related 1.62023
ALB albumin 1.48472
C1R complement component 1, r subcomponent 1.48384
C5AR1 complement component 5a receptor 1 1.45397
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 1.4443
CD79A CD79a molecule, immunoglobulin-associated alpha 1.43025
ENG endoglin 1.37643
CD4 CD4 molecule 1.33589
CD63 CD63 molecule 1.30139
SOX18 SRY (sex determining region Y)-box 18 1.29658
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound 1.27911
TNF tumor necrosis factor 1.25733
IL2 interleukin 2 1.23343
MPO myeloperoxidase 1.22952
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 1.21522
BAK1 BCL2-antagonist/killer 1 1.2031
PRTN3 proteinase 3 1.16906
TAC1 tachykinin, precursor 1 1.16906
MS4A2 membrane-spanning 4-domains, subfamily A, member 2 1.14475
TPT1 tumor protein, translationally-controlled 1 1.13755
ATM ATM serine/threonine kinase 1.13543
MEFV Mediterranean fever 1.10594
IL1RN interleukin 1 receptor antagonist 1.09209
CECR1 cat eye syndrome chromosome region, candidate 1 1.0753
NLRP3 NLR family, pyrin domain containing 3 1.07362
RNASE3 ribonuclease, RNase A family, 3 1.07152
IL6 interleukin 6 1.0383
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.03114
ICAM1 intercellular adhesion molecule 1 0.99697
SELE selectin E 0.99233
PLAT plasminogen activator, tissue 0.987693
PTCRA pre T-cell antigen receptor alpha 0.975903
FOXH1 forkhead box H1 0.975482
MME membrane metallo-endopeptidase 0.952856
S100A12 S100 calcium binding protein A12 0.945354
PFDN4 prefoldin subunit 4 0.94078
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.917611
BDKRB2 bradykinin receptor B2 0.906086
CPN1 carboxypeptidase N, polypeptide 1 0.89623
FOXP3 forkhead box P3 0.891718
C4A complement component 4A (Rodgers blood group) 0.86714
HNMT histamine N-methyltransferase 0.847488
PFN4 profilin family, member 4 0.846669
F2 coagulation factor II (thrombin) 0.843802
F3 coagulation factor III (thromboplastin, tissue factor) 0.826178
CENPB centromere protein B, 80kDa 0.804846
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.804436
ELANE elastase, neutrophil expressed 0.803205
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.796642
PRCP prolylcarboxypeptidase (angiotensinase C) 0.786803
IL1B interleukin 1, beta 0.785165
PFN1 profilin 1 0.783526
SELL selectin L 0.783526
PFN2 profilin 2 0.774523
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.759008
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.751678
NPS neuropeptide S 0.744766
LTC4S leukotriene C4 synthase 0.741923
IL4 interleukin 4 0.737865
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.735433
F11 coagulation factor XI 0.735433
IL5 interleukin 5 0.734217
F8 coagulation factor VIII, procoagulant component 0.733406
SMAD4 SMAD family member 4 0.713198
IL31 interleukin 31 0.69751
VCAM1 vascular cell adhesion molecule 1 0.693499
TGFB1 transforming growth factor, beta 1 0.690694
COL24A1 collagen, type XXIV, alpha 1 0.690694
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 0.690694
CYSLTR2 cysteinyl leukotriene receptor 2 0.688291
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 0.682693
CYSLTR1 cysteinyl leukotriene receptor 1 0.679898
CYCS cytochrome c, somatic 0.679898
VIT vitrin 0.678302
CSN1S1 casein alpha s1 0.67551
C1QBP complement component 1, q subcomponent binding protein 0.661197
MRGPRX2 MAS-related GPR, member X2 0.65288
PELI1 pellino E3 ubiquitin protein ligase 1 0.649718
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.649718
CD69 CD69 molecule 0.649323
MMP9 matrix metallopeptidase 9 0.646165
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.642615
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.638676
VWA7 von Willebrand factor A domain containing 7 0.637889
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.636708
SYK spleen tyrosine kinase 0.633563
OR3A2 olfactory receptor, family 3, subfamily A, member 2 0.632777
OR10J5 olfactory receptor, family 10, subfamily J, member 5 0.632777
CNPY4 canopy FGF signaling regulator 4 0.622575
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.613965
DPP4 dipeptidyl-peptidase 4 0.612011
KIAA0101 KIAA0101 0.607323
LYZ lysozyme 0.605372
IL10 interleukin 10 0.604591
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 0.60303
BLK BLK proto-oncogene, Src family tyrosine kinase 0.6003
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.597571
CCL17 chemokine (C-C motif) ligand 17 0.592895
MASP2 mannan-binding lectin serine peptidase 2 0.589779
VEGFA vascular endothelial growth factor A 0.588612
HRH2 histamine receptor H2 0.57655
C3 complement component 3 0.576161
PLG plasminogen 0.570718
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.569552
IL18 interleukin 18 0.566054
CCL2 chemokine (C-C motif) ligand 2 0.565277
CMA1 chymase 1, mast cell 0.563723
CMC1 C-x(9)-C motif containing 1 0.562169
HLA-C major histocompatibility complex, class I, C 0.561781
KRT1 keratin 1, type II 0.561004
CD86 CD86 molecule 0.548971
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1 0.548583
CEP68 centrosomal protein 68kDa 0.548195
CD209 CD209 molecule 0.546644
MLN motilin 0.545481
SNX24 sorting nexin 24 0.535796
VWF von Willebrand factor 0.531154
CD40 CD40 molecule, TNF receptor superfamily member 5 0.531154
IL1A interleukin 1, alpha 0.524202
MED28 mediator complex subunit 28 0.524202
MOSPD3 motile sperm domain containing 3 0.521117
IL2RA interleukin 2 receptor, alpha 0.520346
CD40LG CD40 ligand 0.508041
CD19 CD19 molecule 0.502292
AFP alpha-fetoprotein 0.491978
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 0.491597
TG thyroglobulin 0.490072
NLRP14 NLR family, pyrin domain containing 14 0.486266
CCL3L1 chemokine (C-C motif) ligand 3-like 1 0.482084
SELPLG selectin P ligand 0.478289
GDF2 growth differentiation factor 2 0.477151
KRTAP10-9 keratin associated protein 10-9 0.474877
TLR2 toll-like receptor 2 0.473361
REN renin 0.471468
POMC proopiomelanocortin 0.469576
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.467684
CD5 CD5 molecule 0.46655
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 0.465038
TPM1 tropomyosin 1 (alpha) 0.463905
S100A9 S100 calcium binding protein A9 0.463149
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) 0.462772
CXCL8 chemokine (C-X-C motif) ligand 8 0.461639
PORCN porcupine homolog (Drosophila) 0.460129
ALOX5 arachidonate 5-lipoxygenase 0.458996
CCR2 chemokine (C-C motif) receptor 2 0.454093
LAT linker for activation of T cells 0.454093
BDKRB1 bradykinin receptor B1 0.452585
RLBP1 retinaldehyde binding protein 1 0.447311
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 0.446935
EPN3 epsin 3 0.446935
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C 0.445805
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) 0.445805
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.445429
TPPP2 tubulin polymerization-promoting protein family member 2 0.440914
NCF4 neutrophil cytosolic factor 4, 40kDa 0.438658
RAX2 retina and anterior neural fold homeobox 2 0.433021
PDCL phosducin-like 0.430393
TRAFD1 TRAF-type zinc finger domain containing 1 0.422515
IGHM immunoglobulin heavy constant mu 0.420266
FAM111B family with sequence similarity 111, member B 0.419517
NRG1 neuregulin 1 0.418394
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) 0.411657
HSF4 heat shock transcription factor 4 0.410161
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.407545
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.407172
CFP complement factor properdin 0.406051
IFNA1 interferon, alpha 1 0.406051
ICAM3 intercellular adhesion molecule 3 0.404557
APITD1 apoptosis-inducing, TAF9-like domain 1 0.403811
HSPG2 heparan sulfate proteoglycan 2 0.400826
INS insulin 0.400453
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 0.398962
FBXL7 F-box and leucine-rich repeat protein 7 0.398216
FLNA filamin A, alpha 0.396725
HBE1 hemoglobin, epsilon 1 0.39598
F7 coagulation factor VII (serum prothrombin conversion accelerator) 0.384451
C2 complement component 2 0.383708
RIMS1 regulating synaptic membrane exocytosis 1 0.381481
S100Z S100 calcium binding protein Z 0.380739
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.379997
CCR3 chemokine (C-C motif) receptor 3 0.379626
INPPL1 inositol polyphosphate phosphatase-like 1 0.377402
TLR4 toll-like receptor 4 0.374068
PRF1 perforin 1 (pore forming protein) 0.372217
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.371477
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase 0.369258
CCL21 chemokine (C-C motif) ligand 21 0.365193
ABI3BP ABI family, member 3 (NESH) binding protein 0.365193
TSPO translocator protein (18kDa) 0.365193
TBXA2R thromboxane A2 receptor 0.363716
SOD2 superoxide dismutase 2, mitochondrial 0.363716
ACRV1 acrosomal vesicle protein 1 0.360764
PDC phosducin 0.360026
DOCK6 dedicator of cytokinesis 6 0.359657
CFB complement factor B 0.357077
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 0.352291
IFNA2 interferon, alpha 2 0.351923
ALPPL2 alkaline phosphatase, placental-like 2 0.35082
ALPP alkaline phosphatase, placental 0.350452
ALPL alkaline phosphatase, liver/bone/kidney 0.350084
HLA-DOB major histocompatibility complex, class II, DO beta 0.346042
SULT4A1 sulfotransferase family 4A, member 1 0.344207
CPOX coproporphyrinogen oxidase 0.342372
CD180 CD180 molecule 0.341639
IL3 interleukin 3 0.340906
CCR7 chemokine (C-C motif) receptor 7 0.340173
NCAM1 neural cell adhesion molecule 1 0.337975
RFXANK regulatory factor X-associated ankyrin-containing protein 0.337975
FTL ferritin, light polypeptide 0.336144
FTH1 ferritin, heavy polypeptide 1 0.336144
IGHE immunoglobulin heavy constant epsilon 0.335778
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 0.335412
PF4 platelet factor 4 0.335046
CD46 CD46 molecule, complement regulatory protein 0.334681
FAM167A family with sequence similarity 167, member A 0.332852
F9 coagulation factor IX 0.33066
RAB4B RAB4B, member RAS oncogene family 0.32993
HDC histidine decarboxylase 0.328469
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 0.32774
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.32774
BAG6 BCL2-associated athanogene 6 0.326646
NOD1 nucleotide-binding oligomerization domain containing 1 0.325916
MMP3 matrix metallopeptidase 3 0.325552
TLR9 toll-like receptor 9 0.32373
INA internexin neuronal intermediate filament protein, alpha 0.318635
SART1 squamous cell carcinoma antigen recognized by T cells 0.313552
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.313189
ADM adrenomedullin 0.307757
HLA-B major histocompatibility complex, class I, B 0.307395
EPX eosinophil peroxidase 0.307033
CFI complement factor I 0.30631
CD68 CD68 molecule 0.305948
LCK LCK proto-oncogene, Src family tyrosine kinase 0.304864
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 0.304142
TBX21 T-box 21 0.301976
KCNK6 potassium channel, two pore domain subfamily K, member 6 0.299452
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.299092
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.296571
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.295492
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD) 0.288668
TIMP1 TIMP metallopeptidase inhibitor 1 0.287593
APP amyloid beta (A4) precursor protein 0.284013
TRPM8 transient receptor potential cation channel, subfamily M, member 8 0.283655
ZFHX3 zinc finger homeobox 3 0.282582
SCP2 sterol carrier protein 2 0.276514
AGER advanced glycosylation end product-specific receptor 0.273308
CSMD3 CUB and Sushi multiple domains 3 0.272953
GGT1 gamma-glutamyltransferase 1 0.272241
F5 coagulation factor V (proaccelerin, labile factor) 0.269043
BICC1 BicC family RNA binding protein 1 0.266558
TSLP thymic stromal lymphopoietin 0.266203
CXCL10 chemokine (C-X-C motif) ligand 10 0.265849
NGF nerve growth factor (beta polypeptide) 0.25983
EEF1B2 eukaryotic translation elongation factor 1 beta 2 0.259477
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 0.259477
ADAT3 adenosine deaminase, tRNA-specific 3 0.259124
PLA2G1B phospholipase A2, group IB (pancreas) 0.256652
EDC3 enhancer of mRNA decapping 3 0.255946
DSG3 desmoglein 3 0.255946
TPO thyroid peroxidase 0.254888
FBLL1 fibrillarin-like 1 0.254183
MVK mevalonate kinase 0.251718
AADACL3 arylacetamide deacetylase-like 3 0.249257
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.247501
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.245396
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene 0.240847
RPS8 ribosomal protein S8 0.240847
CAMK2D calcium/calmodulin-dependent protein kinase II delta 0.239101
FIP1L1 factor interacting with PAPOLA and CPSF1 0.237706
RETN resistin 0.236312
IFNB1 interferon, beta 1, fibroblast 0.23492
THBD thrombomodulin 0.23353
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.229716
ALK anaplastic lymphoma receptor tyrosine kinase 0.229024
TNNI3 troponin I type 3 (cardiac) 0.227642
CAT catalase 0.227297
NLRP12 NLR family, pyrin domain containing 12 0.226607
RHO rhodopsin 0.226262
CCL5 chemokine (C-C motif) ligand 5 0.225229
BMPR1A bone morphogenetic protein receptor, type IA 0.223509
PGD phosphogluconate dehydrogenase 0.221108
HBA2 hemoglobin, alpha 2 0.220766
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.220081
BATF3 basic leucine zipper transcription factor, ATF-like 3 0.218715
PVALB parvalbumin 0.218374
SH2D1A SH2 domain containing 1A 0.217012
CLEC5A C-type lectin domain family 5, member A 0.217012
SCD5 stearoyl-CoA desaturase 5 0.215314
IL15 interleukin 15 0.213283
NDP Norrie disease (pseudoglioma) 0.212945
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.212608
SMTN smoothelin 0.211597
CARS cysteinyl-tRNA synthetase 0.210925
AHSG alpha-2-HS-glycoprotein 0.208914
MYD88 myeloid differentiation primary response 88 0.208579
CDK5RAP3 CDK5 regulatory subunit associated protein 3 0.206913
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2 0.203275
CCL22 chemokine (C-C motif) ligand 22 0.202946
RNF168 ring finger protein 168, E3 ubiquitin protein ligase 0.202618
NEUROD1 neuronal differentiation 1 0.200982
SUOX sulfite oxidase 0.200331
CD47 CD47 molecule 0.199681
PGM1 phosphoglucomutase 1 0.199356
PGAP3 post-GPI attachment to proteins 3 0.199033
SALL1 spalt-like transcription factor 1 0.198709
CD34 CD34 molecule 0.196779
LALBA lactalbumin, alpha- 0.196459
IGHV3-9 immunoglobulin heavy variable 3-9 0.194548
DPT dermatopontin 0.194232
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 0.193285
HLA-DRB3 major histocompatibility complex, class II, DR beta 3 0.192344
SSRP1 structure specific recognition protein 1 0.192344
RLN3 relaxin 3 0.191408
LIG4 ligase IV, DNA, ATP-dependent 0.191408
HLA-A major histocompatibility complex, class I, A 0.190168
NOS3 nitric oxide synthase 3 (endothelial cell) 0.189244
IL21R interleukin 21 receptor 0.188938
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 0.187719
GATA3 GATA binding protein 3 0.18591
POLK polymerase (DNA directed) kappa 0.185016
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.185016
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa 0.18472
ABHD16A abhydrolase domain containing 16A 0.184424
TRIM21 tripartite motif containing 21 0.183835
ACVR2A activin A receptor, type IIA 0.183541
CDH5 cadherin 5, type 2 (vascular endothelium) 0.181798
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1) 0.180937
CTSG cathepsin G 0.177576
VPS9D1 VPS9 domain containing 1 0.177576
GLYATL1 glycine-N-acyltransferase-like 1 0.176757
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 0.175146
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A 0.174093
APOA1 apolipoprotein A-I 0.173832
ELP2 elongator acetyltransferase complex subunit 2 0.173571
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.173314
MBL2 mannose-binding lectin (protein C) 2, soluble 0.171785
FIGF c-fos induced growth factor (vascular endothelial growth factor D) 0.170789
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.170544
ADORA3 adenosine A3 receptor 0.168148
APOH apolipoprotein H (beta-2-glycoprotein I) 0.167224
S100A13 S100 calcium binding protein A13 0.166768
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64) 0.166768
CD80 CD80 molecule 0.165655
COPB2 coatomer protein complex, subunit beta 2 (beta prime) 0.164786
VIP vasoactive intestinal peptide 0.163523
CARD17 caspase recruitment domain family, member 17 0.162306
TCTA T-cell leukemia translocation altered 0.161912
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 0.161912
MT1H metallothionein 1H 0.161716
ACKR3 atypical chemokine receptor 3 0.160761
SRSF1 serine/arginine-rich splicing factor 1 0.159124
EHF ets homologous factor 0.158434