vascular cancer Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A cardiovascular cancer that is located_in blood vessels. (Human Disease Ontology, DOID_175)
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Genes

164 genes co-occuring with the disease vascular cancer in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
MLANA melan-A 1.85046
CD34 CD34 molecule 1.77812
TFE3 transcription factor binding to IGHM enhancer 3 1.75051
HBA1 hemoglobin, alpha 1 1.71818
F8 coagulation factor VIII, procoagulant component 1.69269
HBA2 hemoglobin, alpha 2 1.69224
CALD1 caldesmon 1 1.51194
CAMTA1 calmodulin binding transcription activator 1 1.41183
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 1.3324
WWTR1 WW domain containing transcription regulator 1 1.32891
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.16093
PROX1 prospero homeobox 1 1.13332
FLT4 fms-related tyrosine kinase 4 1.03956
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.03704
PDPN podoplanin 1.02566
TSC2 tuberous sclerosis 2 1.00963
MITF microphthalmia-associated transcription factor 1.00879
SNRK SNF related kinase 0.874919
SYP synaptophysin 0.872872
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 0.872462
ENO2 enolase 2 (gamma, neuronal) 0.854449
RHEB Ras homolog enriched in brain 0.85404
CTSK cathepsin K 0.796642
FGF2 fibroblast growth factor 2 (basic) 0.792541
TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) 0.730976
ESAM endothelial cell adhesion molecule 0.725311
FLT1 fms-related tyrosine kinase 1 0.71925
AJUBA ajuba LIM protein 0.699919
TIAM2 T-cell lymphoma invasion and metastasis 2 0.699919
KDR kinase insert domain receptor 0.669936
CD68 CD68 molecule 0.663578
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.661197
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.641827
S100A5 S100 calcium binding protein A5 0.612792
SMTN smoothelin 0.607323
S100A3 S100 calcium binding protein A3 0.581606
VWF von Willebrand factor 0.578883
SLC35G5 solute carrier family 35, member G5 0.570329
HOXA3 homeobox A3 0.565666
TP53 tumor protein p53 0.559839
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.557509
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) 0.555956
PLA2G12A phospholipase A2, group XIIA 0.548583
GLMN glomulin, FKBP associated protein 0.53928
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 0.538893
VEGFA vascular endothelial growth factor A 0.537731
TYR tyrosinase 0.518034
EWSR1 EWS RNA-binding protein 1 0.509192
VEGFC vascular endothelial growth factor C 0.501527
ANGPT2 angiopoietin 2 0.491597
ENPEP glutamyl aminopeptidase (aminopeptidase A) 0.488549
HOXD3 homeobox D3 0.477909
STAB1 stabilin 1 0.436402
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 0.435651
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 0.420266
ZFP36 ZFP36 ring finger protein 0.418394
TTK TTK protein kinase 0.41465
CDH5 cadherin 5, type 2 (vascular endothelium) 0.413527
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 0.404557
THBD thrombomodulin 0.404184
PAX8 paired box 8 0.401945
MAML1 mastermind-like 1 (Drosophila) 0.392629
ANO1 anoctamin 1, calcium activated chloride channel 0.386308
SOX10 SRY (sex determining region Y)-box 10 0.367779
RREB1 ras responsive element binding protein 1 0.365193
AQP9 aquaporin 9 0.343106
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) 0.337975
FLI1 Fli-1 proto-oncogene, ETS transcription factor 0.336876
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.335046
WT1 Wilms tumor 1 0.333949
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.333583
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.332487
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 0.332121
ANTXR1 anthrax toxin receptor 1 0.32774
CUL2 cullin 2 0.317545
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 0.305587
BID BH3 interacting domain death agonist 0.304864
CCND1 cyclin D1 0.301615
PGR progesterone receptor 0.298011
FES FES proto-oncogene, tyrosine kinase 0.284013
LTBP3 latent transforming growth factor beta binding protein 3 0.276514
ANPEP alanyl (membrane) aminopeptidase 0.275801
GADD45A growth arrest and DNA-damage-inducible, alpha 0.267622
CALB2 calbindin 2 0.267622
TAC1 tachykinin, precursor 1 0.266558
CTAG2 cancer/testis antigen 2 0.261952
PROM1 prominin 1 0.261245
RGS5 regulator of G-protein signaling 5 0.25877
DES desmin 0.257711
PTPRJ protein tyrosine phosphatase, receptor type, J 0.255241
PMEL premelanosome protein 0.249608
LTBP2 latent transforming growth factor beta binding protein 2 0.242245
PLAU plasminogen activator, urokinase 0.241546
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 0.237009
S100A1 S100 calcium binding protein A1 0.235964
HOXA5 homeobox A5 0.223165
ATF2 activating transcription factor 2 0.221793
ARNT aryl hydrocarbon receptor nuclear translocator 0.203933
LAMA2 laminin, alpha 2 0.203604
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) 0.19742
SOX11 SRY (sex determining region Y)-box 11 0.187719
ELL elongation factor RNA polymerase II 0.184424
NF1 neurofibromin 1 0.183248
YAP1 Yes-associated protein 1 0.182957
KRT15 keratin 15, type I 0.177301
PIGF phosphatidylinositol glycan anchor biosynthesis, class F 0.175146
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 0.173314
VIM vimentin 0.171535
MKKS McKusick-Kaufman syndrome 0.169091
S100A2 S100 calcium binding protein A2 0.165217
PDGFC platelet derived growth factor C 0.165217
DNTT DNA nucleotidylexotransferase 0.164786
CLDN11 claudin 11 0.162707
THBS2 thrombospondin 2 0.162505
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.162109
EPAS1 endothelial PAS domain protein 1 0.160021
ALPPL2 alkaline phosphatase, placental-like 2 0.157765
PGLS 6-phosphogluconolactonase 0.143878
APOD apolipoprotein D 0.14379
CHGA chromogranin A 0.143737
MUC6 mucin 6, oligomeric mucus/gel-forming 0.14356
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.143506
WIPF2 WAS/WASL interacting protein family, member 2 0.143213
CLEC3A C-type lectin domain family 3, member A 0.143106
CLEC2B C-type lectin domain family 2, member B 0.143039
PNMT phenylethanolamine N-methyltransferase 0.142748
NEFH neurofilament, heavy polypeptide 0.142714
CLEC10A C-type lectin domain family 10, member A 0.14271
NCAM1 neural cell adhesion molecule 1 0.142351
CLDN5 claudin 5 0.142082
GFAP glial fibrillary acidic protein 0.141537
KRT14 keratin 14, type I 0.141462
MB myoglobin 0.141304
PRCC papillary renal cell carcinoma (translocation-associated) 0.139213
CLTC clathrin, heavy chain (Hc) 0.138125
PAX2 paired box 2 0.13772
B3GAT1 beta-1,3-glucuronyltransferase 1 0.136327
NONO non-POU domain containing, octamer-binding 0.135358
TYRP1 tyrosinase-related protein 1 0.135151
S100P S100 calcium binding protein P 0.135091
MYH11 myosin, heavy chain 11, smooth muscle 0.134392
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.13416
TSC1 tuberous sclerosis 1 0.133444
AMD1 adenosylmethionine decarboxylase 1 0.133083
MAG myelin associated glycoprotein 0.132449
KRT8 keratin 8, type II 0.126581
MUC2 mucin 2, oligomeric mucus/gel-forming 0.123969
KRT5 keratin 5, type II 0.122952
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.120892
KRT20 keratin 20, type I 0.116889
PLAT plasminogen activator, tissue 0.116149
BCL2 B-cell CLL/lymphoma 2 0.115858
S100B S100 calcium binding protein B 0.11287
MUC1 mucin 1, cell surface associated 0.112409
KRT7 keratin 7, type II 0.111947
RTN4R reticulon 4 receptor 0.109909
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 0.10901
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 0.108198
S100A6 S100 calcium binding protein A6 0.107746
AMACR alpha-methylacyl-CoA racemase 0.106208
HNF1B HNF1 homeobox B 0.105216
GPC3 glypican 3 0.098604
KITLG KIT ligand 0.098143
MYOG myogenin (myogenic factor 4) 0.096979