vancomycin-4423 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the vancomycin-4423 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGB androglobin
ADORA1 adenosine A1 receptor
AFF1 AF4/FMR2 family, member 1
AIM1L absent in melanoma 1-like
ALOX12 arachidonate 12-lipoxygenase
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ATP10A ATPase, class V, type 10A
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BCO1 beta-carotene oxygenase 1
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CALCR calcitonin receptor
CCDC71 coiled-coil domain containing 71
CD1E CD1e molecule
CFB complement factor B
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLEC1A C-type lectin domain family 1, member A
CLEC3B C-type lectin domain family 3, member B
CNTNAP2 contactin associated protein-like 2
COL6A1 collagen, type VI, alpha 1
CRP C-reactive protein, pentraxin-related
CT55 cancer/testis antigen 55
CTSZ cathepsin Z
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DIO2 deiodinase, iodothyronine, type II
DOCK9 dedicator of cytokinesis 9
DRD1 dopamine receptor D1
DUSP1 dual specificity phosphatase 1
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
EPN1 epsin 1
ERC1 ELKS/RAB6-interacting/CAST family member 1
FSCN3 fascin actin-bundling protein 3, testicular
GARNL3 GTPase activating Rap/RanGAP domain-like 3
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GPER1 G protein-coupled estrogen receptor 1
GRIK5 glutamate receptor, ionotropic, kainate 5
GRIP2 glutamate receptor interacting protein 2
GRPR gastrin-releasing peptide receptor
HSPB3 heat shock 27kDa protein 3
ING2 inhibitor of growth family, member 2
KIAA1109 KIAA1109
KIAA1462 KIAA1462
LDB2 LIM domain binding 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LINC00652 long intergenic non-protein coding RNA 652
LYZL6 lysozyme-like 6
MAL mal, T-cell differentiation protein
MET MET proto-oncogene, receptor tyrosine kinase
NF1 neurofibromin 1
NOTCH3 notch 3
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PAOX polyamine oxidase (exo-N4-amino)
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PCDHB11 protocadherin beta 11
PCDHGA8 protocadherin gamma subfamily A, 8
PEG10 paternally expressed 10
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PID1 phosphotyrosine interaction domain containing 1
PKP2 plakophilin 2
PLCL2 phospholipase C-like 2
POU5F1B POU class 5 homeobox 1B
PPARA peroxisome proliferator-activated receptor alpha
PPARD peroxisome proliferator-activated receptor delta
PPP1R12B protein phosphatase 1, regulatory subunit 12B
PRAMEF12 PRAME family member 12
PRDM1 PR domain containing 1, with ZNF domain
PSCA prostate stem cell antigen
RAB6A RAB6A, member RAS oncogene family
RAB6B RAB6B, member RAS oncogene family
RARA retinoic acid receptor, alpha
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RUNDC3A RUN domain containing 3A
S100A8 S100 calcium binding protein A8
SAG S-antigen; retina and pineal gland (arrestin)
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPPL2B signal peptide peptidase like 2B
SSPN sarcospan
SSX3 synovial sarcoma, X breakpoint 3
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STAB2 stabilin 2
SYNPO synaptopodin
T T, brachyury homolog (mouse)
TBC1D2 TBC1 domain family, member 2
TFDP3 transcription factor Dp family, member 3
TMLHE trimethyllysine hydroxylase, epsilon
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TNPO2 transportin 2
TPP1 tripeptidyl peptidase I
TRIO trio Rho guanine nucleotide exchange factor
TTC38 tetratricopeptide repeat domain 38
VWA5A von Willebrand factor A domain containing 5A
ZNF236 zinc finger protein 236
ZNF335 zinc finger protein 335
ZNF646 zinc finger protein 646
ZRSR1 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1

decreased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ACAD10 acyl-CoA dehydrogenase family, member 10
ADCY7 adenylate cyclase 7
ALS2CL ALS2 C-terminal like
AOC2 amine oxidase, copper containing 2 (retina-specific)
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APLP1 amyloid beta (A4) precursor-like protein 1
BHLHE41 basic helix-loop-helix family, member e41
C10ORF95 chromosome 10 open reading frame 95
C11ORF30 chromosome 11 open reading frame 30
C11ORF63 chromosome 11 open reading frame 63
C8ORF60 chromosome 8 open reading frame 60
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CALML5 calmodulin-like 5
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC85C coiled-coil domain containing 85C
CDHR2 cadherin-related family member 2
CENPQ centromere protein Q
CFAP45 cilia and flagella associated protein 45
CIDEC cell death-inducing DFFA-like effector c
CNTN1 contactin 1
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DENND4A DENN/MADD domain containing 4A
DGKQ diacylglycerol kinase, theta 110kDa
EN2 engrailed homeobox 2
EPHX2 epoxide hydrolase 2, cytoplasmic
ERCC6 excision repair cross-complementation group 6
ERN1 endoplasmic reticulum to nucleus signaling 1
ETV6 ets variant 6
FADS2 fatty acid desaturase 2
FAM155A family with sequence similarity 155, member A
FBXL8 F-box and leucine-rich repeat protein 8
FBXO2 F-box protein 2
FILIP1L filamin A interacting protein 1-like
FLJ11710 uncharacterized protein FLJ11710
GADD45G growth arrest and DNA-damage-inducible, gamma
GAN gigaxonin
GPR143 G protein-coupled receptor 143
GPR157 G protein-coupled receptor 157
GRAMD1C GRAM domain containing 1C
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H1D histone cluster 1, H1d
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
HYAL3 hyaluronoglucosaminidase 3
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
ITGA10 integrin, alpha 10
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITPKB inositol-trisphosphate 3-kinase B
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KREMEN2 kringle containing transmembrane protein 2
LINC00597 long intergenic non-protein coding RNA 597
LMNB1 lamin B1
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MEGF6 multiple EGF-like-domains 6
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MTCP1 mature T-cell proliferation 1
MUC3A mucin 3A, cell surface associated
MUC6 mucin 6, oligomeric mucus/gel-forming
MX2 MX dynamin-like GTPase 2
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
NEUROD1 neuronal differentiation 1
NKX3-2 NK3 homeobox 2
NLRX1 NLR family member X1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PEX26 peroxisomal biogenesis factor 26
PLXNB3 plexin B3
POU4F2 POU class 4 homeobox 2
PTPRS protein tyrosine phosphatase, receptor type, S
PVRL3 poliovirus receptor-related 3
QPCTL glutaminyl-peptide cyclotransferase-like
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RORC RAR-related orphan receptor C
RPH3A rabphilin 3A
SCN1B sodium channel, voltage gated, type I beta subunit
SEC14L5 SEC14-like 5 (S. cerevisiae)
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SIPA1 signal-induced proliferation-associated 1
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SPRR2B small proline-rich protein 2B
SYNC syncoilin, intermediate filament protein
TAS2R10 taste receptor, type 2, member 10
TDRD1 tudor domain containing 1
TMEM120B transmembrane protein 120B
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TTLL1 tubulin tyrosine ligase-like family member 1
TUBA4B tubulin, alpha 4b
VPS9D1 VPS9 domain containing 1
ZNF480 zinc finger protein 480
ZNF552 zinc finger protein 552
ZNF623 zinc finger protein 623
ZNF747 zinc finger protein 747
ZSWIM1 zinc finger, SWIM-type containing 1