valproic acid_homo sapiens_gpl6244_gse23909 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule]_[organism]_[GEO platform]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE23909
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Genes

439 genes differentially expressed following the valproic acid_homo sapiens_gpl6244_gse23909 small molecule perturbation from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCA9 ATP-binding cassette, sub-family A (ABC1), member 9
ACKR4 atypical chemokine receptor 4
ACSL5 acyl-CoA synthetase long-chain family member 5
ACYP2 acylphosphatase 2, muscle type
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18
ADI1 acireductone dioxygenase 1
ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit
ALYREF Aly/REF export factor
ANGPTL1 angiopoietin-like 1
ANLN anillin, actin binding protein
ANXA3 annexin A3
APOBEC3A_B APOBEC3A and APOBEC3B deletion hybrid
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARHGAP11A Rho GTPase activating protein 11A
ARHGAP11B Rho GTPase activating protein 11B
ARHGAP24 Rho GTPase activating protein 24
ARSB arylsulfatase B
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATF5 activating transcription factor 5
AURKA aurora kinase A
AVEN apoptosis, caspase activation inhibitor
B3GALTL beta 1,3-galactosyltransferase-like
B3GNT5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
BCL6B B-cell CLL/lymphoma 6, member B
BHLHE40 basic helix-loop-helix family, member e40
BMX BMX non-receptor tyrosine kinase
BNC2 basonuclin 2
BRPF3 bromodomain and PHD finger containing, 3
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C10ORF32-ASMT C10orf32-ASMT readthrough (NMD candidate)
C1QTNF5 C1q and tumor necrosis factor related protein 5
C1QTNF6 C1q and tumor necrosis factor related protein 6
C1RL complement component 1, r subcomponent-like
CARD6 caspase recruitment domain family, member 6
CASC5 cancer susceptibility candidate 5
CASP1 caspase 1, apoptosis-related cysteine peptidase
CBFB core-binding factor, beta subunit
CCDC80 coiled-coil domain containing 80
CCL2 chemokine (C-C motif) ligand 2
CCNA2 cyclin A2
CCNB1 cyclin B1
CCNB2 cyclin B2
CD200 CD200 molecule
CD34 CD34 molecule
CDC20 cell division cycle 20
CDCA3 cell division cycle associated 3
CDCA8 cell division cycle associated 8
CDK1 cyclin-dependent kinase 1
CENPE centromere protein E, 312kDa
CENPF centromere protein F, 350/400kDa
CENPO centromere protein O
CHD3 chromodomain helicase DNA binding protein 3
CISD2 CDGSH iron sulfur domain 2
CLEC14A C-type lectin domain family 14, member A
CLEC1A C-type lectin domain family 1, member A
CLSPN claspin
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
CMC2 C-x(9)-C motif containing 2
CNTNAP3B contactin associated protein-like 3B
CPNE5 copine V
CREBBP CREB binding protein
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTSO cathepsin O
CTSS cathepsin S
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL2 chemokine (C-X-C motif) ligand 2
CXORF36 chromosome X open reading frame 36
CYTH2 cytohesin 2
DEPDC1 DEP domain containing 1
DHRS3 dehydrogenase/reductase (SDR family) member 3
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DLL4 delta-like 4 (Drosophila)
DMTN dematin actin binding protein
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
DPP3 dipeptidyl-peptidase 3
EFCAB2 EF-hand calcium binding domain 2
EFNA1 ephrin-A1
EFNB2 ephrin-B2
EMP1 epithelial membrane protein 1
EPC1 enhancer of polycomb homolog 1 (Drosophila)
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EVI2B ecotropic viral integration site 2B
FAIM Fas apoptotic inhibitory molecule
FAM124B family with sequence similarity 124B
FAM136A family with sequence similarity 136, member A
FAM217B family with sequence similarity 217, member B
FAM57A family with sequence similarity 57, member A
FBXO5 F-box protein 5
FERMT3 fermitin family member 3
FOXM1 forkhead box M1
FUS FUS RNA binding protein
GABPB1 GA binding protein transcription factor, beta subunit 1
GDF3 growth differentiation factor 3
GIMAP2 GTPase, IMAP family member 2
GIMAP6 GTPase, IMAP family member 6
GIMAP7 GTPase, IMAP family member 7
GJA4 gap junction protein, alpha 4, 37kDa
GJA5 gap junction protein, alpha 5, 40kDa
GLT8D2 glycosyltransferase 8 domain containing 2
GMEB1 glucocorticoid modulatory element binding protein 1
GPR146 G protein-coupled receptor 146
GPX7 glutathione peroxidase 7
GTF2I general transcription factor IIi
GTF2IRD2B GTF2I repeat domain containing 2B
GTF3C6 general transcription factor IIIC, polypeptide 6, alpha 35kDa
GTSE1 G-2 and S-phase expressed 1
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HIST1H2AB histone cluster 1, H2ab
HIST1H2BB histone cluster 1, H2bb
HIST1H2BC histone cluster 1, H2bc
HIST1H2BK histone cluster 1, H2bk
HMGA2 high mobility group AT-hook 2
HMGN2 high mobility group nucleosomal binding domain 2
HMMR hyaluronan-mediated motility receptor (RHAMM)
HOMER3 homer scaffolding protein 3
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
ICAM1 intercellular adhesion molecule 1
IFI35 interferon-induced protein 35
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IL1RL1 interleukin 1 receptor-like 1
IL33 interleukin 33
IQGAP3 IQ motif containing GTPase activating protein 3
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KAT6B K(lysine) acetyltransferase 6B
KBTBD2 kelch repeat and BTB (POZ) domain containing 2
KEAP1 kelch-like ECH-associated protein 1
KIAA1524 KIAA1524
KIF15 kinesin family member 15
KIF18B kinesin family member 18B
KIF20A kinesin family member 20A
KIF20B kinesin family member 20B
KIF23 kinesin family member 23
KIF2C kinesin family member 2C
KIF4A kinesin family member 4A
KIFC1 kinesin family member C1
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLHL3 kelch-like family member 3
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LCORL ligand dependent nuclear receptor corepressor-like
LGALS9 lectin, galactoside-binding, soluble, 9
LGALS9C lectin, galactoside-binding, soluble, 9C
LMNB1 lamin B1
LOC100129518 uncharacterized LOC100129518
LRIG3 leucine-rich repeats and immunoglobulin-like domains 3
LRRC17 leucine rich repeat containing 17
LRRC70 leucine rich repeat containing 70
LTBP2 latent transforming growth factor beta binding protein 2
MCM9 minichromosome maintenance complex component 9
MCTP1 multiple C2 domains, transmembrane 1
MILR1 mast cell immunoglobulin-like receptor 1
MKI67 marker of proliferation Ki-67
MLIP muscular LMNA-interacting protein
MPDU1 mannose-P-dolichol utilization defect 1
MRAP2 melanocortin 2 receptor accessory protein 2
MSRA methionine sulfoxide reductase A
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
N4BP2 NEDD4 binding protein 2
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2
NCAPH non-SMC condensin I complex, subunit H
NCOA5 nuclear receptor coactivator 5
NDC80 NDC80 kinetochore complex component
NEXN nexilin (F actin binding protein)
NIPAL2 NIPA-like domain containing 2
NMI N-myc (and STAT) interactor
NNMT nicotinamide N-methyltransferase
NOD1 nucleotide-binding oligomerization domain containing 1
NOS1 nitric oxide synthase 1 (neuronal)
NOX4 NADPH oxidase 4
NRP1 neuropilin 1
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
NSUN4 NOP2/Sun domain family, member 4
NUF2 NUF2, NDC80 kinetochore complex component
NUPR1 nuclear protein, transcriptional regulator, 1
OMD osteomodulin
OTC ornithine carbamoyltransferase
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PALMD palmdelphin
PBDC1 polysaccharide biosynthesis domain containing 1
PBK PDZ binding kinase
PBLD phenazine biosynthesis-like protein domain containing
PBRM1 polybromo 1
PDCD1LG2 programmed cell death 1 ligand 2
PHF11 PHD finger protein 11
PHF19 PHD finger protein 19
PIGW phosphatidylinositol glycan anchor biosynthesis, class W
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLK1 polo-like kinase 1
PLK4 polo-like kinase 4
PMF1 polyamine-modulated factor 1
POLDIP3 polymerase (DNA-directed), delta interacting protein 3
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POSTN periostin, osteoblast specific factor
PRC1 protein regulator of cytokinesis 1
PRKCDBP protein kinase C, delta binding protein
PTCHD4 patched domain containing 4
RACGAP1 Rac GTPase activating protein 1
RAMP2 receptor (G protein-coupled) activity modifying protein 2
RFTN2 raftlin family member 2
RGS7BP regulator of G-protein signaling 7 binding protein
RPL22L1 ribosomal protein L22-like 1
RRM2 ribonucleotide reductase M2
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SAMD9L sterile alpha motif domain containing 9-like
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SGK494 uncharacterized serine/threonine-protein kinase SgK494
SHCBP1 SHC SH2-domain binding protein 1
SIRPB2 signal-regulatory protein beta 2
SKA1 spindle and kinetochore associated complex subunit 1
SKA3 spindle and kinetochore associated complex subunit 3
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SMC1A structural maintenance of chromosomes 1A
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SNCAIP synuclein, alpha interacting protein
SNORD14E small nucleolar RNA, C/D box 14E
SPAG7 sperm associated antigen 7
SPARCL1 SPARC-like 1 (hevin)
SPC25 SPC25, NDC80 kinetochore complex component
STAG1 stromal antigen 1
STS steroid sulfatase (microsomal), isozyme S
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SUSD1 sushi domain containing 1
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3
TFRC transferrin receptor
THSD7A thrombospondin, type I, domain containing 7A
TIMELESS timeless circadian clock
TLR3 toll-like receptor 3
TM4SF18 transmembrane 4 L six family member 18
TMEM106A transmembrane protein 106A
TMEM117 transmembrane protein 117
TMEM255B transmembrane protein 255B
TMEM87A transmembrane protein 87A
TOE1 target of EGR1, member 1 (nuclear)
TOX thymocyte selection-associated high mobility group box
TP53 tumor protein p53
TP53I3 tumor protein p53 inducible protein 3
TPX2 TPX2, microtubule-associated
TRA2A transformer 2 alpha homolog (Drosophila)
TRIM22 tripartite motif containing 22
TRIP13 thyroid hormone receptor interactor 13
TUBA1C tubulin, alpha 1c
TYMS thymidylate synthetase
USP18 ubiquitin specific peptidase 18
USP41 ubiquitin specific peptidase 41
VCAM1 vascular cell adhesion molecule 1
VEPH1 ventricular zone expressed PH domain-containing 1
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae)
XAF1 XIAP associated factor 1
XBP1 X-box binding protein 1
ZFX zinc finger protein, X-linked
ZNF423 zinc finger protein 423
ZNF618 zinc finger protein 618

decreased expression

Symbol Name
ACSS3 acyl-CoA synthetase short-chain family member 3
ADGRB2 adhesion G protein-coupled receptor B2
ALDOC aldolase C, fructose-bisphosphate
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ANO5 anoctamin 5
APLP1 amyloid beta (A4) precursor-like protein 1
AREG amphiregulin
ARRDC4 arrestin domain containing 4
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide
BEX1 brain expressed, X-linked 1
BRINP1 bone morphogenetic protein/retinoic acid inducible neural-specific 1
C10ORF107 chromosome 10 open reading frame 107
CA12 carbonic anhydrase XII
CACNG7 calcium channel, voltage-dependent, gamma subunit 7
CADM3 cell adhesion molecule 3
CCDC110 coiled-coil domain containing 110
CCDC148 coiled-coil domain containing 148
CCDC68 coiled-coil domain containing 68
CCL23 chemokine (C-C motif) ligand 23
CD24 CD24 molecule
CD274 CD274 molecule
CDON cell adhesion associated, oncogene regulated
CHRM4 cholinergic receptor, muscarinic 4
CKB creatine kinase, brain
CLGN calmegin
CMKLR1 chemerin chemokine-like receptor 1
CPA4 carboxypeptidase A4
CRMP1 collapsin response mediator protein 1
CXADR coxsackie virus and adenovirus receptor
CYFIP2 cytoplasmic FMR1 interacting protein 2
DENND2C DENN/MADD domain containing 2C
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC5G DnaJ (Hsp40) homolog, subfamily C, member 5 gamma
DNER delta/notch-like EGF repeat containing
DNM3 dynamin 3
DPYSL5 dihydropyrimidinase-like 5
DUSP10 dual specificity phosphatase 10
DZIP1 DAZ interacting zinc finger protein 1
EDNRB endothelin receptor type B
EFNA3 ephrin-A3
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ELOVL4 ELOVL fatty acid elongase 4
ENO2 enolase 2 (gamma, neuronal)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
F2RL2 coagulation factor II (thrombin) receptor-like 2
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FAIM2 Fas apoptotic inhibitory molecule 2
FAM160A1 family with sequence similarity 160, member A1
FAM229B family with sequence similarity 229, member B
FAM69A family with sequence similarity 69, member A
FBXO16 F-box protein 16
FGFR4 fibroblast growth factor receptor 4
FLRT3 fibronectin leucine rich transmembrane protein 3
FRAS1 Fraser extracellular matrix complex subunit 1
FXYD7 FXYD domain containing ion transport regulator 7
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta
GALNT13 polypeptide N-acetylgalactosaminyltransferase 13
GALNT16 polypeptide N-acetylgalactosaminyltransferase 16
GDAP1 ganglioside induced differentiation associated protein 1
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GK glycerol kinase
GK3P glycerol kinase 3 pseudogene
GLB1L2 galactosidase, beta 1-like 2
GLIPR2 GLI pathogenesis-related 2
GMFG glia maturation factor, gamma
GPC3 glypican 3
GPR155 G protein-coupled receptor 155
GPR160 G protein-coupled receptor 160
GPX3 glutathione peroxidase 3
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HPSE heparanase
HYKK hydroxylysine kinase
IFI30 interferon, gamma-inducible protein 30
IQGAP2 IQ motif containing GTPase activating protein 2
ITGA11 integrin, alpha 11
ITGA8 integrin, alpha 8
ITGA9 integrin, alpha 9
ITM2A integral membrane protein 2A
ITM2C integral membrane protein 2C
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1
KIF1A kinesin family member 1A
L1CAM L1 cell adhesion molecule
LAYN layilin
LOC100132147 uncharacterized LOC100132147
LOC642533 uncharacterized LOC642533
LPPR4 lipid phosphate phosphatase-related protein type 4
LRRN1 leucine rich repeat neuronal 1
LRRN3 leucine rich repeat neuronal 3
MAL2 mal, T-cell differentiation protein 2 (gene/pseudogene)
MAP1A microtubule-associated protein 1A
MAP9 microtubule-associated protein 9
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MLF1 myeloid leukemia factor 1
NCAM1 neural cell adhesion molecule 1
NCAM2 neural cell adhesion molecule 2
NDNF neuron-derived neurotrophic factor
NEFH neurofilament, heavy polypeptide
NELL2 NEL-like 2 (chicken)
NEO1 neogenin 1
NID2 nidogen 2 (osteonidogen)
NME5 NME/NM23 family member 5
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NOSTRIN nitric oxide synthase trafficking
NRIP3 nuclear receptor interacting protein 3
PAIP2B poly(A) binding protein interacting protein 2B
PAQR5 progestin and adipoQ receptor family member V
PARM1 prostate androgen-regulated mucin-like protein 1
PDE2A phosphodiesterase 2A, cGMP-stimulated
PDE5A phosphodiesterase 5A, cGMP-specific
PDGFC platelet derived growth factor C
PEG10 paternally expressed 10
PKP2 plakophilin 2
PLAT plasminogen activator, tissue
PLCD1 phospholipase C, delta 1
PLEKHH2 pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
PLS1 plastin 1
PNMA2 paraneoplastic Ma antigen 2
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPM1N protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
PRKCB protein kinase C, beta
PTPRU protein tyrosine phosphatase, receptor type, U
RAB39B RAB39B, member RAS oncogene family
RAB3B RAB3B, member RAS oncogene family
RBM11 RNA binding motif protein 11
RERG RAS-like, estrogen-regulated, growth inhibitor
RHOF ras homolog family member F (in filopodia)
RNF157 ring finger protein 157
ROPN1L rhophilin associated tail protein 1-like
RRAGD Ras-related GTP binding D
RUNDC3A RUN domain containing 3A
SATB2 SATB homeobox 2
SCAMP5 secretory carrier membrane protein 5
SCUBE1 signal peptide, CUB domain, EGF-like 1
SEPT3 septin 3
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SFRP1 secreted frizzled-related protein 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC29A4 solute carrier family 29 (equilibrative nucleoside transporter), member 4
SLC2A12 solute carrier family 2 (facilitated glucose transporter), member 12
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC38A3 solute carrier family 38, member 3
SLC46A3 solute carrier family 46, member 3
SLC4A11 solute carrier family 4, sodium borate transporter, member 11
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SNAP25 synaptosomal-associated protein, 25kDa
SPAG6 sperm associated antigen 6
STARD5 StAR-related lipid transfer (START) domain containing 5
STC1 stanniocalcin 1
STMN2 stathmin 2
SV2A synaptic vesicle glycoprotein 2A
SYT1 synaptotagmin I
SYT13 synaptotagmin XIII
TC2N tandem C2 domains, nuclear
TEX15 testis expressed 15
TEX9 testis expressed 9
THY1 Thy-1 cell surface antigen
TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2
TMEM108 transmembrane protein 108
TMEM232 transmembrane protein 232
TMEM38B transmembrane protein 38B
TMEM56 transmembrane protein 56
TOM1L1 target of myb1 (chicken)-like 1
TSHZ2 teashirt zinc finger homeobox 2
TSPAN33 tetraspanin 33
TTLL7 tubulin tyrosine ligase-like family member 7
TUBB2B tubulin, beta 2B class IIb
TXNDC16 thioredoxin domain containing 16
TYMSOS TYMS opposite strand
UNC13A unc-13 homolog A (C. elegans)
VAT1L vesicle amine transport 1-like
VAV3 vav 3 guanine nucleotide exchange factor
VSNL1 visinin-like 1
WDR17 WD repeat domain 17
ZNF204P zinc finger protein 204, pseudogene
ZNF277 zinc finger protein 277