valproic acid_homo sapiens_gpl4685_gse45587 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule]_[organism]_[GEO platform]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE45587
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Genes

259 genes differentially expressed following the valproic acid_homo sapiens_gpl4685_gse45587 small molecule perturbation from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACLY ATP citrate lyase
ACTB actin, beta
ACTG1 actin gamma 1
ADNP activity-dependent neuroprotector homeobox
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
ANGEL2 angel homolog 2 (Drosophila)
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
ASCL1 achaete-scute family bHLH transcription factor 1
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
BCLAF1 BCL2-associated transcription factor 1
BUB3 BUB3 mitotic checkpoint protein
C1QBP complement component 1, q subcomponent binding protein
CANX calnexin
CAPRIN1 cell cycle associated protein 1
CCNA2 cyclin A2
CCNB2 cyclin B2
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CDK4 cyclin-dependent kinase 4
CERS2 ceramide synthase 2
CHTOP chromatin target of PRMT1
CIRBP cold inducible RNA binding protein
CNBP CCHC-type zinc finger, nucleic acid binding protein
CNOT7 CCR4-NOT transcription complex, subunit 7
COIL coilin
COQ9 coenzyme Q9
CRH corticotropin releasing hormone
CSE1L CSE1 chromosome segregation 1-like (yeast)
CTCF CCCTC-binding factor (zinc finger protein)
CYB561 cytochrome b561
DARS aspartyl-tRNA synthetase
DCTN6 dynactin 6
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DHPS deoxyhypusine synthase
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15
DKC1 dyskeratosis congenita 1, dyskerin
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DOK4 docking protein 4
EIF1 eukaryotic translation initiation factor 1
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
EIF3D eukaryotic translation initiation factor 3, subunit D
EIF4A1 eukaryotic translation initiation factor 4A1
EIF4A2 eukaryotic translation initiation factor 4A2
EIF4B eukaryotic translation initiation factor 4B
EIF4EBP2P1 eukaryotic translation initiation factor 4E binding protein 2 pseudogene 1
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
EIF5 eukaryotic translation initiation factor 5
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ENO1 enolase 1, (alpha)
EPAS1 endothelial PAS domain protein 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM163A family with sequence similarity 163, member A
FAM60A family with sequence similarity 60, member A
FSCN1 fascin actin-bundling protein 1
GANAB glucosidase, alpha; neutral AB
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GATA3 GATA binding protein 3
GHITM growth hormone inducible transmembrane protein
GMNN geminin, DNA replication inhibitor
GNAS GNAS complex locus
GTF3A general transcription factor IIIA
H2AFZ H2A histone family, member Z
H3F3AP4 H3 histone, family 3A, pseudogene 4
HAND2-AS1 HAND2 antisense RNA 1 (head to head)
HDLBP high density lipoprotein binding protein
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HINT1 histidine triad nucleotide binding protein 1
HMGB1 high mobility group box 1
HMGB2 high mobility group box 2
HMGN2 high mobility group nucleosomal binding domain 2
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
HNRNPF heterogeneous nuclear ribonucleoprotein F
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9)
HNRNPR heterogeneous nuclear ribonucleoprotein R
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA8 heat shock 70kDa protein 8
HSPA9 heat shock 70kDa protein 9 (mortalin)
HSPE1 heat shock 10kDa protein 1
ICT1 immature colon carcinoma transcript 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ILF2 interleukin enhancer binding factor 2
INTS7 integrator complex subunit 7
ISL1 ISL LIM homeobox 1
ITM2B integral membrane protein 2B
IVNS1ABP influenza virus NS1A binding protein
KARS lysyl-tRNA synthetase
KEAP1 kelch-like ECH-associated protein 1
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KPNB1 karyopherin (importin) beta 1
LAMP5 lysosomal-associated membrane protein family, member 5
LRBA LPS-responsive vesicle trafficking, beach and anchor containing
LRRN3 leucine rich repeat neuronal 3
LSM12 LSM12 homolog (S. cerevisiae)
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LUC7L2 LUC7-like 2 (S. cerevisiae)
MAB21L1 mab-21-like 1 (C. elegans)
MAB21L2 mab-21-like 2 (C. elegans)
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like
MARCKS myristoylated alanine-rich protein kinase C substrate
MATR3 matrin 3
MCM2 minichromosome maintenance complex component 2
MCM4 minichromosome maintenance complex component 4
MCM5 minichromosome maintenance complex component 5
MCM7 minichromosome maintenance complex component 7
MEIS2 Meis homeobox 2
METTL7A methyltransferase like 7A
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
MORF4 mortality factor 4 (pseudogene)
MORF4L1 mortality factor 4 like 1
MRPL15 mitochondrial ribosomal protein L15
MRPL3 mitochondrial ribosomal protein L3
MRPS7 mitochondrial ribosomal protein S7
MTMR11 myotubularin related protein 11
MTUS1 microtubule associated tumor suppressor 1
MYO1B myosin IB
NACA nascent polypeptide-associated complex alpha subunit
NCL nucleolin
NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NONO non-POU domain containing, octamer-binding
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NRP1 neuropilin 1
NUP50 nucleoporin 50kDa
ODC1 ornithine decarboxylase 1
PARP2 poly (ADP-ribose) polymerase 2
PCDH9 protocadherin 9
PCNA proliferating cell nuclear antigen
PDHB pyruvate dehydrogenase (lipoamide) beta
PEF1 penta-EF-hand domain containing 1
PITPNB phosphatidylinositol transfer protein, beta
PLK1 polo-like kinase 1
PNN pinin, desmosome associated protein
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
POMP proteasome maturation protein
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
PPP1R8 protein phosphatase 1, regulatory subunit 8
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRMT1 protein arginine methyltransferase 1
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PTBP1 polypyrimidine tract binding protein 1
PTPRO protein tyrosine phosphatase, receptor type, O
PUF60 poly-U binding splicing factor 60KDa
PUM2 pumilio RNA-binding family member 2
RAD21 RAD21 homolog (S. pombe)
RAN RAN, member RAS oncogene family
RANBP1 RAN binding protein 1
RB1CC1 RB1-inducible coiled-coil 1
RBBP4 retinoblastoma binding protein 4
RBM25 RNA binding motif protein 25
RBM39 RNA binding motif protein 39
RFK riboflavin kinase
RGS4 regulator of G-protein signaling 4
RGS5 regulator of G-protein signaling 5
RHOA ras homolog family member A
RHOB ras homolog family member B
RPL10 ribosomal protein L10
RPL11 ribosomal protein L11
RPL18AP3 ribosomal protein L18a pseudogene 3
RPL24 ribosomal protein L24
RPL29 ribosomal protein L29
RPL34 ribosomal protein L34
RPL41 ribosomal protein L41
RPS13 ribosomal protein S13
RPS2 ribosomal protein S2
RPS24 ribosomal protein S24
RPS26 ribosomal protein S26
RPS6 ribosomal protein S6
RRM2 ribonucleotide reductase M2
RSL1D1 ribosomal L1 domain containing 1
RSRC2 arginine/serine-rich coiled-coil 2
SELT selenoprotein T
SEPHS1 selenophosphate synthetase 1
SERBP1 SERPINE1 mRNA binding protein 1
SET SET nuclear proto-oncogene
SF3B2 splicing factor 3b, subunit 2, 145kDa
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
SLC38A2 solute carrier family 38, member 2
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
SMC4 structural maintenance of chromosomes 4
SMYD2 SET and MYND domain containing 2
SNRPE small nuclear ribonucleoprotein polypeptide E
SON SON DNA binding protein
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae)
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SRSF1 serine/arginine-rich splicing factor 1
SRSF10 serine/arginine-rich splicing factor 10
SRSF2 serine/arginine-rich splicing factor 2
SRSF3 serine/arginine-rich splicing factor 3
SRSF5 serine/arginine-rich splicing factor 5
SRSF6 serine/arginine-rich splicing factor 6
SRSF7 serine/arginine-rich splicing factor 7
STAG2 stromal antigen 2
SUMO2 small ubiquitin-like modifier 2
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae)
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
TARS threonyl-tRNA synthetase
TCF4 transcription factor 4
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TLE4 transducin-like enhancer of split 4
TMOD1 tropomodulin 1
TMPO thymopoietin
TMX2 thioredoxin-related transmembrane protein 2
TMX4 thioredoxin-related transmembrane protein 4
TOB1 transducer of ERBB2, 1
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast)
TPT1 tumor protein, translationally-controlled 1
TPX2 TPX2, microtubule-associated
TRA2B transformer 2 beta homolog (Drosophila)
TRIB2 tribbles pseudokinase 2
TSPAN3 tetraspanin 3
TUBA1B tubulin, alpha 1b
TUBA1C tubulin, alpha 1c
TUBB tubulin, beta class I
TYMS thymidylate synthetase
U2AF1 U2 small nuclear RNA auxiliary factor 1
UBE2C ubiquitin-conjugating enzyme E2C
UBE2I ubiquitin-conjugating enzyme E2I
UBQLN2 ubiquilin 2
UCK2 uridine-cytidine kinase 2
UFC1 ubiquitin-fold modifier conjugating enzyme 1
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X
VCP valosin containing protein
VDAC1 voltage-dependent anion channel 1
VDAC1P1 voltage-dependent anion channel 1 pseudogene 1
XPO1 exportin 1
XPOT exportin, tRNA
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
YBX1 Y box binding protein 1
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZBTB1 zinc finger and BTB domain containing 1
ZC3H11A zinc finger CCCH-type containing 11A
ZC3H4 zinc finger CCCH-type containing 4
ZFAND5 zinc finger, AN1-type domain 5
ZMYND11 zinc finger, MYND-type containing 11
ZNF207 zinc finger protein 207