valproic acid-994 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the valproic acid-994 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVR1B activin A receptor, type IB
AGFG1 ArfGAP with FG repeats 1
AKAP12 A kinase (PRKA) anchor protein 12
ALPK1 alpha-kinase 1
APP amyloid beta (A4) precursor protein
ARMCX2 armadillo repeat containing, X-linked 2
ARRB1 arrestin, beta 1
ASPHD1 aspartate beta-hydroxylase domain containing 1
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
BTBD7 BTB (POZ) domain containing 7
BTN2A2 butyrophilin, subfamily 2, member A2
C1ORF56 chromosome 1 open reading frame 56
CARF calcium responsive transcription factor
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC28B coiled-coil domain containing 28B
CCDC9 coiled-coil domain containing 9
CDC25C cell division cycle 25C
CDK13 cyclin-dependent kinase 13
CEP97 centrosomal protein 97kDa
CLGN calmegin
DBN1 drebrin 1
DSC2 desmocollin 2
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EFNB3 ephrin-B3
FAM184A family with sequence similarity 184, member A
FHL1 four and a half LIM domains 1
FOXN3 forkhead box N3
FRMD1 FERM domain containing 1
FSCN1 fascin actin-bundling protein 1
GK glycerol kinase
GOLGA8B golgin A8 family, member B
GPR153 G protein-coupled receptor 153
GRK5 G protein-coupled receptor kinase 5
GSAP gamma-secretase activating protein
GSDMB gasdermin B
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa
HEG1 heart development protein with EGF-like domains 1
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HLA-F major histocompatibility complex, class I, F
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
ITGB5 integrin, beta 5
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KCTD2 potassium channel tetramerization domain containing 2
KIF5C kinesin family member 5C
LCMT2 leucine carboxyl methyltransferase 2
LDB1 LIM domain binding 1
LHX6 LIM homeobox 6
LMAN1 lectin, mannose-binding, 1
LPP LIM domain containing preferred translocation partner in lipoma
LZTR1 leucine-zipper-like transcription regulator 1
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5
MTAP methylthioadenosine phosphorylase
MTCP1 mature T-cell proliferation 1
MTSS1 metastasis suppressor 1
NDRG2 NDRG family member 2
NF2 neurofibromin 2 (merlin)
PDE4A phosphodiesterase 4A, cAMP-specific
PDE8B phosphodiesterase 8B
PEX26 peroxisomal biogenesis factor 26
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLK4 polo-like kinase 4
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PTCH1 patched 1
PTPN12 protein tyrosine phosphatase, non-receptor type 12
RAB29 RAB29, member RAS oncogene family
RAB8B RAB8B, member RAS oncogene family
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RNF170 ring finger protein 170
RPL13P5 ribosomal protein L13 pseudogene 5
RTN2 reticulon 2
S100A8 S100 calcium binding protein A8
SAMD9 sterile alpha motif domain containing 9
SCAI suppressor of cancer cell invasion
SFTPB surfactant protein B
SFXN3 sideroflexin 3
SIK3 SIK family kinase 3
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa
SORT1 sortilin 1
SOS2 son of sevenless homolog 2 (Drosophila)
SWAP70 SWAP switching B-cell complex 70kDa subunit
TRIM21 tripartite motif containing 21
TRIP11 thyroid hormone receptor interactor 11
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TTC28 tetratricopeptide repeat domain 28
TTC33 tetratricopeptide repeat domain 33
UBXN1 UBX domain protein 1
ULBP2 UL16 binding protein 2
USP27X ubiquitin specific peptidase 27, X-linked
VGF VGF nerve growth factor inducible
WAPAL wings apart-like homolog (Drosophila)
WDTC1 WD and tetratricopeptide repeats 1
ZCCHC24 zinc finger, CCHC domain containing 24
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF204P zinc finger protein 204, pseudogene
ZNF34 zinc finger protein 34
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACVR2B activin A receptor, type IIB
AEN apoptosis enhancing nuclease
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALKBH1 alkB, alkylation repair homolog 1 (E. coli)
ANP32A-IT1 ANP32A intronic transcript 1
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ASCC2 activating signal cointegrator 1 complex subunit 2
BAGE B melanoma antigen
C10ORF2 chromosome 10 open reading frame 2
C19ORF24 chromosome 19 open reading frame 24
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CASZ1 castor zinc finger 1
CCNO cyclin O
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CPTP ceramide-1-phosphate transfer protein
CRABP2 cellular retinoic acid binding protein 2
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CRYBG3 beta-gamma crystallin domain containing 3
CSTA cystatin A (stefin A)
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DENND4A DENN/MADD domain containing 4A
DERL2 derlin 2
DHRS3 dehydrogenase/reductase (SDR family) member 3
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DYNLT1 dynein, light chain, Tctex-type 1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FOSL1 FOS-like antigen 1
FOXC1 forkhead box C1
FTO fat mass and obesity associated
GAS8 growth arrest-specific 8
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GLCE glucuronic acid epimerase
GMEB1 glucocorticoid modulatory element binding protein 1
GPR87 G protein-coupled receptor 87
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IRF7 interferon regulatory factor 7
KAT2A K(lysine) acetyltransferase 2A
KIAA0125 KIAA0125
LAMA3 laminin, alpha 3
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPK12 mitogen-activated protein kinase 12
MBTPS2 membrane-bound transcription factor peptidase, site 2
MFSD11 major facilitator superfamily domain containing 11
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MTA2 metastasis associated 1 family, member 2
MUM1 melanoma associated antigen (mutated) 1
NAE1 NEDD8 activating enzyme E1 subunit 1
NDE1 nudE neurodevelopment protein 1
NHLRC2 NHL repeat containing 2
NKAIN1 Na+/K+ transporting ATPase interacting 1
NME6 NME/NM23 nucleoside diphosphate kinase 6
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae)
NRGN neurogranin (protein kinase C substrate, RC3)
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
PARD6A par-6 family cell polarity regulator alpha
PCTP phosphatidylcholine transfer protein
PER3 period circadian clock 3
PGP phosphoglycolate phosphatase
PLEC plectin
PMP22 peripheral myelin protein 22
PPAN peter pan homolog (Drosophila)
PPT2 palmitoyl-protein thioesterase 2
PTTG3P pituitary tumor-transforming 3, pseudogene
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB33B RAB33B, member RAS oncogene family
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RAD51AP1 RAD51 associated protein 1
RFTN1 raftlin, lipid raft linker 1
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SCAP SREBF chaperone
SEC24B SEC24 family member B
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SPIDR scaffolding protein involved in DNA repair
TEX264 testis expressed 264
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TMEM106B transmembrane protein 106B
TMEM132A transmembrane protein 132A
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TSNAX translin-associated factor X
TSPAN1 tetraspanin 1
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
ZBTB39 zinc finger and BTB domain containing 39
ZFP30 ZFP30 zinc finger protein
ZNF282 zinc finger protein 282
ZNF552 zinc finger protein 552
ZNF767P zinc finger family member 767, pseudogene
ZNF813 zinc finger protein 813
ZNF83 zinc finger protein 83
ZSCAN5A zinc finger and SCAN domain containing 5A