valproic acid-6982 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the valproic acid-6982 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AFAP1 actin filament associated protein 1
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
AMH anti-Mullerian hormone
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ASTN2 astrotactin 2
ATF6B activating transcription factor 6 beta
BCAS1 breast carcinoma amplified sequence 1
BST2 bone marrow stromal cell antigen 2
CCPG1 cell cycle progression 1
CD44 CD44 molecule (Indian blood group)
CDC25A cell division cycle 25A
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CNOT8 CCR4-NOT transcription complex, subunit 8
CRYBG3 beta-gamma crystallin domain containing 3
CT55 cancer/testis antigen 55
CTAGE5 CTAGE family, member 5
DST dystonin
DSTYK dual serine/threonine and tyrosine protein kinase
EGR1 early growth response 1
EHD1 EH-domain containing 1
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1
ELSPBP1 epididymal sperm binding protein 1
FGF2 fibroblast growth factor 2 (basic)
FOSL2 FOS-like antigen 2
GAP43 growth associated protein 43
GAS6 growth arrest-specific 6
GHRHR growth hormone releasing hormone receptor
GLS2 glutaminase 2 (liver, mitochondrial)
GMEB1 glucocorticoid modulatory element binding protein 1
HAMP hepcidin antimicrobial peptide
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HFE hemochromatosis
HOXC5 homeobox C5
IFNAR1 interferon (alpha, beta and omega) receptor 1
IGL immunoglobulin lambda locus
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL11 interleukin 11
IL7R interleukin 7 receptor
INADL InaD-like (Drosophila)
ING1 inhibitor of growth family, member 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KLF6 Kruppel-like factor 6
KLHL28 kelch-like family member 28
KREMEN2 kringle containing transmembrane protein 2
KRT19P2 keratin 19 pseudogene 2
LAMP1 lysosomal-associated membrane protein 1
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LMNA lamin A/C
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAP4 microtubule-associated protein 4
MED6 mediator complex subunit 6
MORN1 MORN repeat containing 1
MTA1 metastasis associated 1
MTCP1 mature T-cell proliferation 1
MYO1F myosin IF
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NACA2 nascent polypeptide-associated complex alpha subunit 2
NCAPH2 non-SMC condensin II complex, subunit H2
NIPAL2 NIPA-like domain containing 2
NXT2 nuclear transport factor 2-like export factor 2
NYNRIN NYN domain and retroviral integrase containing
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3
OPRM1 opioid receptor, mu 1
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAIP2B poly(A) binding protein interacting protein 2B
PARVA parvin, alpha
PDE4A phosphodiesterase 4A, cAMP-specific
PGBD5 piggyBac transposable element derived 5
PKNOX2 PBX/knotted 1 homeobox 2
PORCN porcupine homolog (Drosophila)
PRO2964 uncharacterized protein PRO2964
PTGES prostaglandin E synthase
RAD54B RAD54 homolog B (S. cerevisiae)
RECQL5 RecQ protein-like 5
REEP1 receptor accessory protein 1
RER1 retention in endoplasmic reticulum sorting receptor 1
RORC RAR-related orphan receptor C
RRBP1 ribosome binding protein 1
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SFTPC surfactant protein C
SIPA1 signal-induced proliferation-associated 1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SND1-IT1 SND1 intronic transcript 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SSPN sarcospan
SYCE1L synaptonemal complex central element protein 1-like
TAOK1 TAO kinase 1
TCHH trichohyalin
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TJAP1 tight junction associated protein 1 (peripheral)
TMC5 transmembrane channel-like 5
TPP1 tripeptidyl peptidase I
XK X-linked Kx blood group
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZNF419 zinc finger protein 419
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
ADGRA3 adhesion G protein-coupled receptor A3
AGBL5 ATP/GTP binding protein-like 5
ANXA1 annexin A1
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATF3 activating transcription factor 3
BCAR3 breast cancer anti-estrogen resistance 3
BCOR BCL6 corepressor
C11ORF68 chromosome 11 open reading frame 68
C19ORF40 chromosome 19 open reading frame 40
C1ORF56 chromosome 1 open reading frame 56
C5ORF45 chromosome 5 open reading frame 45
C9ORF40 chromosome 9 open reading frame 40
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CBX4 chromobox homolog 4
CCDC176 coiled-coil domain containing 176
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CENPB centromere protein B, 80kDa
CGREF1 cell growth regulator with EF-hand domain 1
CIR1 corepressor interacting with RBPJ, 1
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CUEDC1 CUE domain containing 1
DGKD diacylglycerol kinase, delta 130kDa
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
ELMO3 engulfment and cell motility 3
EPPK1 epiplakin 1
ERO1L ERO1-like (S. cerevisiae)
FAM114A2 family with sequence similarity 114, member A2
FAM63A family with sequence similarity 63, member A
FBXL15 F-box and leucine-rich repeat protein 15
FBXO31 F-box protein 31
FMO4 flavin containing monooxygenase 4
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GBAS glioblastoma amplified sequence
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HINFP histone H4 transcription factor
HIST1H2AJ histone cluster 1, H2aj
HMHA1 histocompatibility (minor) HA-1
IGSF1 immunoglobulin superfamily, member 1
INCENP inner centromere protein antigens 135/155kDa
JMJD4 jumonji domain containing 4
LINC00115 long intergenic non-protein coding RNA 115
LMNB1 lamin B1
LRRC20 leucine rich repeat containing 20
LZTR1 leucine-zipper-like transcription regulator 1
MBTD1 mbt domain containing 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MGC12488
MTCL1 microtubule crosslinking factor 1
MYL5 myosin, light chain 5, regulatory
MYO1E myosin IE
NABP2 nucleic acid binding protein 2
NINL ninein-like
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PCSK7 proprotein convertase subtilisin/kexin type 7
PHGDH phosphoglycerate dehydrogenase
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PPP6R2 protein phosphatase 6, regulatory subunit 2
RAB17 RAB17, member RAS oncogene family
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RAD54L RAD54-like (S. cerevisiae)
RFTN1 raftlin, lipid raft linker 1
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF31 ring finger protein 31
SH3GLB2 SH3-domain GRB2-like endophilin B2
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SNX16 sorting nexin 16
SOX12 SRY (sex determining region Y)-box 12
SP1 Sp1 transcription factor
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like
SUN2 Sad1 and UNC84 domain containing 2
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TESK1 testis-specific kinase 1
TMEM57 transmembrane protein 57
TMEM8A transmembrane protein 8A
TRABD TraB domain containing
TRIM25 tripartite motif containing 25
TROAP trophinin associated protein
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
UBTF upstream binding transcription factor, RNA polymerase I
VASH2 vasohibin 2
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR13 WD repeat domain 13
WDR60 WD repeat domain 60
WDR62 WD repeat domain 62
WDR7 WD repeat domain 7
YEATS2 YEATS domain containing 2
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZC3H12A zinc finger CCCH-type containing 12A
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZFP30 ZFP30 zinc finger protein
ZMYM1 zinc finger, MYM-type 1
ZNF273 zinc finger protein 273
ZNF350 zinc finger protein 350
ZNF552 zinc finger protein 552
ZNF557 zinc finger protein 557
ZNF668 zinc finger protein 668