valproic acid-6969 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the valproic acid-6969 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACYP1 acylphosphatase 1, erythrocyte (common) type
ADAM22 ADAM metallopeptidase domain 22
ADGRL1 adhesion G protein-coupled receptor L1
AK2 adenylate kinase 2
ANKMY1 ankyrin repeat and MYND domain containing 1
ANKRD36 ankyrin repeat domain 36
ARL2BP ADP-ribosylation factor-like 2 binding protein
ATF6B activating transcription factor 6 beta
ATN1 atrophin 1
AURKA aurora kinase A
BGN biglycan
BTN2A2 butyrophilin, subfamily 2, member A2
C7ORF69 chromosome 7 open reading frame 69
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCDC28B coiled-coil domain containing 28B
CD6 CD6 molecule
CDH10 cadherin 10, type 2 (T2-cadherin)
CDON cell adhesion associated, oncogene regulated
CHD3 chromodomain helicase DNA binding protein 3
COL10A1 collagen, type X, alpha 1
CYLD cylindromatosis (turban tumor syndrome)
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DGAT1 diacylglycerol O-acyltransferase 1
DIO2 deiodinase, iodothyronine, type II
DPYSL4 dihydropyrimidinase-like 4
DRD2 dopamine receptor D2
EDA ectodysplasin A
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
ELOVL5 ELOVL fatty acid elongase 5
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
ESR1 estrogen receptor 1
FBXL8 F-box and leucine-rich repeat protein 8
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GAMT guanidinoacetate N-methyltransferase
GEMIN7 gem (nuclear organelle) associated protein 7
GLS2 glutaminase 2 (liver, mitochondrial)
GLTSCR1 glioma tumor suppressor candidate region gene 1
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR153 G protein-coupled receptor 153
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GSK3A glycogen synthase kinase 3 alpha
HIPK2 homeodomain interacting protein kinase 2
HIST1H2BO histone cluster 1, H2bo
HLA-A major histocompatibility complex, class I, A
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
HYI hydroxypyruvate isomerase (putative)
IFNAR1 interferon (alpha, beta and omega) receptor 1
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
JRK Jrk homolog (mouse)
KIF13B kinesin family member 13B
KRT19P2 keratin 19 pseudogene 2
LAMC3 laminin, gamma 3
LRRC40 leucine rich repeat containing 40
MAGOH2P mago-nashi homolog 2, pseudogene
MAP4 microtubule-associated protein 4
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAPT microtubule-associated protein tau
MIP major intrinsic protein of lens fiber
MTA1 metastasis associated 1
MVD mevalonate (diphospho) decarboxylase
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
MYO10 myosin X
NAV2 neuron navigator 2
NCKAP1 NCK-associated protein 1
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NFIB nuclear factor I/B
OPTN optineurin
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PTPRN protein tyrosine phosphatase, receptor type, N
RAB36 RAB36, member RAS oncogene family
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RUNDC3B RUN domain containing 3B
RUNX1 runt-related transcription factor 1
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SETD8 SET domain containing (lysine methyltransferase) 8
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SIKE1 suppressor of IKBKE 1
SIPA1 signal-induced proliferation-associated 1
SIRT4 sirtuin 4
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SNCG synuclein, gamma (breast cancer-specific protein 1)
SP2 Sp2 transcription factor
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TBC1D22A TBC1 domain family, member 22A
TTC28 tetratricopeptide repeat domain 28
TTC9 tetratricopeptide repeat domain 9
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
WNT1 wingless-type MMTV integration site family, member 1
ZFX zinc finger protein, X-linked
ZMAT5 zinc finger, matrin-type 5
ZNF654 zinc finger protein 654
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
AGO3 argonaute RISC catalytic component 3
AKTIP AKT interacting protein
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ARHGAP5 Rho GTPase activating protein 5
ARMC7 armadillo repeat containing 7
ARRB2 arrestin, beta 2
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BACE1 beta-site APP-cleaving enzyme 1
BAK1 BCL2-antagonist/killer 1
BPGM 2,3-bisphosphoglycerate mutase
C19ORF40 chromosome 19 open reading frame 40
C1ORF112 chromosome 1 open reading frame 112
C3ORF52 chromosome 3 open reading frame 52
CBX7 chromobox homolog 7
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CFD complement factor D (adipsin)
CLSPN claspin
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DDIT3 DNA-damage-inducible transcript 3
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DEAF1 DEAF1 transcription factor
DENND4B DENN/MADD domain containing 4B
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13
DOCK1 dedicator of cytokinesis 1
EFHD2 EF-hand domain family, member D2
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
FA2H fatty acid 2-hydroxylase
FAM114A2 family with sequence similarity 114, member A2
FAM118A family with sequence similarity 118, member A
FHOD1 formin homology 2 domain containing 1
FOSL1 FOS-like antigen 1
FUZ fuzzy planar cell polarity protein
GLCE glucuronic acid epimerase
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
HAUS6 HAUS augmin-like complex, subunit 6
HMHA1 histocompatibility (minor) HA-1
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
IRF2 interferon regulatory factor 2
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
JMJD4 jumonji domain containing 4
KAT2A K(lysine) acetyltransferase 2A
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KIAA0556 KIAA0556
KLHL36 kelch-like family member 36
LZTR1 leucine-zipper-like transcription regulator 1
MAPK12 mitogen-activated protein kinase 12
MBIP MAP3K12 binding inhibitory protein 1
MED24 mediator complex subunit 24
METTL16 methyltransferase like 16
MFSD12 major facilitator superfamily domain containing 12
MPI mannose phosphate isomerase
MXD3 MAX dimerization protein 3
MYH9 myosin, heavy chain 9, non-muscle
NDRG1 N-myc downstream regulated 1
NRGN neurogranin (protein kinase C substrate, RC3)
OTUD3 OTU deubiquitinase 3
PGP phosphoglycolate phosphatase
PLD3 phospholipase D family, member 3
POLH polymerase (DNA directed), eta
PTTG3P pituitary tumor-transforming 3, pseudogene
RAB5B RAB5B, member RAS oncogene family
RIPK4 receptor-interacting serine-threonine kinase 4
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF31 ring finger protein 31
RPL13P5 ribosomal protein L13 pseudogene 5
SARS2 seryl-tRNA synthetase 2, mitochondrial
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC46A3 solute carrier family 46, member 3
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SPRYD7 SPRY domain containing 7
SSFA2 sperm specific antigen 2
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TDRD7 tudor domain containing 7
TGDS TDP-glucose 4,6-dehydratase
THAP1 THAP domain containing, apoptosis associated protein 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM184C transmembrane protein 184C
TMEM57 transmembrane protein 57
TPRA1 transmembrane protein, adipocyte asscociated 1
TRIM25 tripartite motif containing 25
TRIP10 thyroid hormone receptor interactor 10
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
URM1 ubiquitin related modifier 1
VGF VGF nerve growth factor inducible
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
WBP2 WW domain binding protein 2
XKR8 XK, Kell blood group complex subunit-related family, member 8
YEATS2 YEATS domain containing 2
ZNF211 zinc finger protein 211
ZNF254 zinc finger protein 254
ZNF280D zinc finger protein 280D
ZNF552 zinc finger protein 552
ZNF8 zinc finger protein 8