valproic acid-6941 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the valproic acid-6941 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABHD14A abhydrolase domain containing 14A
ADAM17 ADAM metallopeptidase domain 17
AHI1 Abelson helper integration site 1
AK2 adenylate kinase 2
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ARNT aryl hydrocarbon receptor nuclear translocator
ASPHD1 aspartate beta-hydroxylase domain containing 1
B4GALT7 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7
C17ORF85 chromosome 17 open reading frame 85
CASZ1 castor zinc finger 1
CCL21 chemokine (C-C motif) ligand 21
CD151 CD151 molecule (Raph blood group)
CDC14A cell division cycle 14A
CDC25C cell division cycle 25C
CFLAR CASP8 and FADD-like apoptosis regulator
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLUAP1 clusterin associated protein 1
CYR61 cysteine-rich, angiogenic inducer, 61
DCAF11 DDB1 and CUL4 associated factor 11
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DHODH dihydroorotate dehydrogenase (quinone)
DLC1 DLC1 Rho GTPase activating protein
DMC1 DNA meiotic recombinase 1
DOK4 docking protein 4
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
EDA ectodysplasin A
EXOC7 exocyst complex component 7
FAM134A family with sequence similarity 134, member A
FAM184A family with sequence similarity 184, member A
FBXO9 F-box protein 9
FCF1 FCF1 rRNA-processing protein
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGF18 fibroblast growth factor 18
FKBP10 FK506 binding protein 10, 65 kDa
GAB2 GRB2-associated binding protein 2
GPR137 G protein-coupled receptor 137
GRB10 growth factor receptor-bound protein 10
HEG1 heart development protein with EGF-like domains 1
HIST1H4D histone cluster 1, H4d
HLA-J major histocompatibility complex, class I, J (pseudogene)
HOXC10 homeobox C10
HPS1 Hermansky-Pudlak syndrome 1
IFT122 intraflagellar transport 122
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
ING1 inhibitor of growth family, member 1
INHBA inhibin, beta A
IQSEC1 IQ motif and Sec7 domain 1
KERA keratocan
KIAA0556 KIAA0556
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LIN7A lin-7 homolog A (C. elegans)
MAPK12 mitogen-activated protein kinase 12
MAST2 microtubule associated serine/threonine kinase 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEIS1 Meis homeobox 1
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MMRN2 multimerin 2
MYO1E myosin IE
NAIP NLR family, apoptosis inhibitory protein
NEK9 NIMA-related kinase 9
NFE2L3 nuclear factor, erythroid 2-like 3
NFX1 nuclear transcription factor, X-box binding 1
NFYA nuclear transcription factor Y, alpha
NLK nemo-like kinase
OAZ3 ornithine decarboxylase antizyme 3
OPTN optineurin
PAX2 paired box 2
PDE4DIP phosphodiesterase 4D interacting protein
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1
PLLP plasmolipin
PROSC proline synthetase co-transcribed homolog (bacterial)
PRUNE prune exopolyphosphatase
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RGS10 regulator of G-protein signaling 10
RNF19B ring finger protein 19B
RNF24 ring finger protein 24
RPAP1 RNA polymerase II associated protein 1
RPLP2 ribosomal protein, large, P2
RPS3A ribosomal protein S3A
S100A4 S100 calcium binding protein A4
SBF1 SET binding factor 1
SIM2 single-minded family bHLH transcription factor 2
SMAD3 SMAD family member 3
SOAT2 sterol O-acyltransferase 2
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TDRD1 tudor domain containing 1
TFG TRK-fused gene
TLN2 talin 2
TMEM62 transmembrane protein 62
TRAK1 trafficking protein, kinesin binding 1
TUBA3C tubulin, alpha 3c
UBE2I ubiquitin-conjugating enzyme E2I
UBQLN4 ubiquilin 4
VAV2 vav 2 guanine nucleotide exchange factor
ZBTB6 zinc finger and BTB domain containing 6
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZNF141 zinc finger protein 141

decreased expression

Symbol Name
ADCY6 adenylate cyclase 6
ANKZF1 ankyrin repeat and zinc finger domain containing 1
AP3M2 adaptor-related protein complex 3, mu 2 subunit
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARMC6 armadillo repeat containing 6
ASL argininosuccinate lyase
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BBS10 Bardet-Biedl syndrome 10
CAMKMT calmodulin-lysine N-methyltransferase
CAPN5 calpain 5
CCDC176 coiled-coil domain containing 176
CDKN2AIP CDKN2A interacting protein
CEP72 centrosomal protein 72kDa
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CTAGE9 CTAGE family, member 9
CUEDC1 CUE domain containing 1
DBR1 debranching RNA lariats 1
EAF2 ELL associated factor 2
EDC4 enhancer of mRNA decapping 4
EFNA1 ephrin-A1
ERN2 endoplasmic reticulum to nucleus signaling 2
EYA2 EYA transcriptional coactivator and phosphatase 2
FANCE Fanconi anemia, complementation group E
FBRS fibrosin
FLJ10038 uncharacterized protein FLJ10038
FZD4 frizzled class receptor 4
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNL1 guanine nucleotide binding protein-like 1
GPR87 G protein-coupled receptor 87
GPRC5C G protein-coupled receptor, class C, group 5, member C
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
HOXC13 homeobox C13
IFITM1 interferon induced transmembrane protein 1
IL4R interleukin 4 receptor
IRF2BP1 interferon regulatory factor 2 binding protein 1
KIAA0894 KIAA0894 protein
KIF16B kinesin family member 16B
KRI1 KRI1 homolog (S. cerevisiae)
LAMA3 laminin, alpha 3
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MNS1 meiosis-specific nuclear structural 1
MORC3 MORC family CW-type zinc finger 3
NCAM2 neural cell adhesion molecule 2
NCS1 neuronal calcium sensor 1
NES nestin
NRGN neurogranin (protein kinase C substrate, RC3)
NUBP2 nucleotide binding protein 2
ODF2 outer dense fiber of sperm tails 2
OTUD3 OTU deubiquitinase 3
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PACS1 phosphofurin acidic cluster sorting protein 1
PAQR6 progestin and adipoQ receptor family member VI
PC pyruvate carboxylase
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PODXL2 podocalyxin-like 2
POR P450 (cytochrome) oxidoreductase
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PRSS22 protease, serine, 22
PTPRG protein tyrosine phosphatase, receptor type, G
REEP4 receptor accessory protein 4
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPAP2 RNA polymerase II associated protein 2
RPH3AL rabphilin 3A-like (without C2 domains)
SARS2 seryl-tRNA synthetase 2, mitochondrial
SETD1B SET domain containing 1B
SETD8 SET domain containing (lysine methyltransferase) 8
SFXN1 sideroflexin 1
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC22A18 solute carrier family 22, member 18
SMA4 glucuronidase, beta pseudogene
SND1-IT1 SND1 intronic transcript 1
SPINK4 serine peptidase inhibitor, Kazal type 4
STAG3L1 stromal antigen 3-like 1 (pseudogene)
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TCTN2 tectonic family member 2
TMEM183A transmembrane protein 183A
TPRA1 transmembrane protein, adipocyte asscociated 1
TRIM45 tripartite motif containing 45
TRPV1 transient receptor potential cation channel, subfamily V, member 1
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UBE2L6 ubiquitin-conjugating enzyme E2L 6
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WWC2 WW and C2 domain containing 2
XKR8 XK, Kell blood group complex subunit-related family, member 8
ZBTB39 zinc finger and BTB domain containing 39
ZFHX3 zinc finger homeobox 3
ZNF219 zinc finger protein 219
ZNF324 zinc finger protein 324
ZNF668 zinc finger protein 668
ZNF767P zinc finger family member 767, pseudogene
ZSCAN9 zinc finger and SCAN domain containing 9