valproic acid-6934 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the valproic acid-6934 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ARHGAP4 Rho GTPase activating protein 4
ARMCX2 armadillo repeat containing, X-linked 2
ATAD5 ATPase family, AAA domain containing 5
AUTS2 autism susceptibility candidate 2
BLVRA biliverdin reductase A
BMP7 bone morphogenetic protein 7
C11ORF30 chromosome 11 open reading frame 30
C21ORF91 chromosome 21 open reading frame 91
C2ORF27A chromosome 2 open reading frame 27A
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CRYBG3 beta-gamma crystallin domain containing 3
CUL2 cullin 2
CUL4B cullin 4B
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
CXADR coxsackie virus and adenovirus receptor
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DSE dermatan sulfate epimerase
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EHD2 EH-domain containing 2
ELL elongation factor RNA polymerase II
ELOVL5 ELOVL fatty acid elongase 5
EPOR erythropoietin receptor
F8 coagulation factor VIII, procoagulant component
FBXO2 F-box protein 2
FGGY FGGY carbohydrate kinase domain containing
FYN FYN proto-oncogene, Src family tyrosine kinase
GLI3 GLI family zinc finger 3
GLRX glutaredoxin (thioltransferase)
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPC4 glypican 4
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HOXA4 homeobox A4
HSPA12A heat shock 70kDa protein 12A
IL15RA interleukin 15 receptor, alpha
INPP1 inositol polyphosphate-1-phosphatase
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
IQSEC2 IQ motif and Sec7 domain 2
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KDM4B lysine (K)-specific demethylase 4B
KIF5C kinesin family member 5C
KREMEN2 kringle containing transmembrane protein 2
LPCAT3 lysophosphatidylcholine acyltransferase 3
LPPR2 lipid phosphate phosphatase-related protein type 2
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAPK7 mitogen-activated protein kinase 7
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MTSS1 metastasis suppressor 1
MUC3B mucin 3B, cell surface associated
NFX1 nuclear transcription factor, X-box binding 1
NUDCD3 NudC domain containing 3
OPTN optineurin
PAX8 paired box 8
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDE4A phosphodiesterase 4A, cAMP-specific
PECR peroxisomal trans-2-enoyl-CoA reductase
PGAP1 post-GPI attachment to proteins 1
PGM1 phosphoglucomutase 1
PHC3 polyhomeotic homolog 3 (Drosophila)
PHKG1 phosphorylase kinase, gamma 1 (muscle)
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POLG polymerase (DNA directed), gamma
PROS1 protein S (alpha)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTRF polymerase I and transcript release factor
RGS2 regulator of G-protein signaling 2
RNF24 ring finger protein 24
RPS3A ribosomal protein S3A
RRAGD Ras-related GTP binding D
SALL2 spalt-like transcription factor 2
SCAPER S-phase cyclin A-associated protein in the ER
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SPAG4 sperm associated antigen 4
STX1A syntaxin 1A (brain)
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
SYCP2 synaptonemal complex protein 2
SYT17 synaptotagmin XVII
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TMPO thymopoietin
TRAF5 TNF receptor-associated factor 5
TRAK1 trafficking protein, kinesin binding 1
ULBP2 UL16 binding protein 2
VLDLR very low density lipoprotein receptor
WASL Wiskott-Aldrich syndrome-like
WWTR1 WW domain containing transcription regulator 1
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF235 zinc finger protein 235
ZNF318 zinc finger protein 318
ZNF428 zinc finger protein 428
ZNF442 zinc finger protein 442
ZNF609 zinc finger protein 609
ZNF646 zinc finger protein 646

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ATF3 activating transcription factor 3
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
C16ORF59 chromosome 16 open reading frame 59
CAMKMT calmodulin-lysine N-methyltransferase
CCDC88C coiled-coil domain containing 88C
CDK3 cyclin-dependent kinase 3
CENPQ centromere protein Q
CRABP1 cellular retinoic acid binding protein 1
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CXORF21 chromosome X open reading frame 21
CXORF56 chromosome X open reading frame 56
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DAPK3 death-associated protein kinase 3
DCP1A decapping mRNA 1A
DDIT3 DNA-damage-inducible transcript 3
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNM1 dynamin 1
DSCAM Down syndrome cell adhesion molecule
DSPP dentin sialophosphoprotein
ECI1 enoyl-CoA delta isomerase 1
FAM53B family with sequence similarity 53, member B
FGD6 FYVE, RhoGEF and PH domain containing 6
FOSL1 FOS-like antigen 1
GRTP1 growth hormone regulated TBC protein 1
GSTM2 glutathione S-transferase mu 2 (muscle)
HIST1H2AG histone cluster 1, H2ag
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BC histone cluster 1, H2bc
HIST1H2BE histone cluster 1, H2be
IP6K2 inositol hexakisphosphate kinase 2
KDM5C lysine (K)-specific demethylase 5C
KIAA0894 KIAA0894 protein
KLF3 Kruppel-like factor 3 (basic)
KPTN kaptin (actin binding protein)
LRRC8E leucine rich repeat containing 8 family, member E
LY6D lymphocyte antigen 6 complex, locus D
MAN2C1 mannosidase, alpha, class 2C, member 1
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MIS18BP1 MIS18 binding protein 1
MTRF1 mitochondrial translational release factor 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MXD3 MAX dimerization protein 3
NDE1 nudE neurodevelopment protein 1
NDRG1 N-myc downstream regulated 1
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NOL6 nucleolar protein 6 (RNA-associated)
NR1H3 nuclear receptor subfamily 1, group H, member 3
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OPN3 opsin 3
PACS1 phosphofurin acidic cluster sorting protein 1
PDLIM2 PDZ and LIM domain 2 (mystique)
PEMT phosphatidylethanolamine N-methyltransferase
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PODXL2 podocalyxin-like 2
POLR1B polymerase (RNA) I polypeptide B, 128kDa
PTDSS2 phosphatidylserine synthase 2
PYGB phosphorylase, glycogen; brain
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RPAP2 RNA polymerase II associated protein 2
SARS2 seryl-tRNA synthetase 2, mitochondrial
SECISBP2 SECIS binding protein 2
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SIL1 SIL1 nucleotide exchange factor
SLC41A3 solute carrier family 41, member 3
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPAG7 sperm associated antigen 7
SPIDR scaffolding protein involved in DNA repair
SPINK4 serine peptidase inhibitor, Kazal type 4
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM39B transmembrane protein 39B
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TTC23 tetratricopeptide repeat domain 23
TUBGCP5 tubulin, gamma complex associated protein 5
UBTD1 ubiquitin domain containing 1
UBXN6 UBX domain protein 6
USP18 ubiquitin specific peptidase 18
VASH2 vasohibin 2
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZBED8 zinc finger, BED-type containing 8
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF124 zinc finger protein 124
ZNF250 zinc finger protein 250
ZNF276 zinc finger protein 276
ZNF329 zinc finger protein 329
ZNF33B zinc finger protein 33B
ZNF816 zinc finger protein 816