valproic acid-629 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the valproic acid-629 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADD2 adducin 2 (beta)
ADRBK2 adrenergic, beta, receptor kinase 2
AHCYL2 adenosylhomocysteinase-like 2
ARG2 arginase 2
ARHGAP29 Rho GTPase activating protein 29
ARHGAP44 Rho GTPase activating protein 44
ARMT1 acidic residue methyltransferase 1
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
CA12 carbonic anhydrase XII
CADM1 cell adhesion molecule 1
CASZ1 castor zinc finger 1
CD22 CD22 molecule
CDK19 cyclin-dependent kinase 19
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
DCAF11 DDB1 and CUL4 associated factor 11
DDAH2 dimethylarginine dimethylaminohydrolase 2
DFNB31 deafness, autosomal recessive 31
DGKA diacylglycerol kinase, alpha 80kDa
DMTN dematin actin binding protein
DNAH3 dynein, axonemal, heavy chain 3
EDC3 enhancer of mRNA decapping 3
EID1 EP300 interacting inhibitor of differentiation 1
EXTL3 exostosin-like glycosyltransferase 3
FAM117A family with sequence similarity 117, member A
FERMT2 fermitin family member 2
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FGFR1 fibroblast growth factor receptor 1
FUT2 fucosyltransferase 2 (secretor status included)
FYN FYN proto-oncogene, Src family tyrosine kinase
GABARAPL1 GABA(A) receptor-associated protein like 1
GLRX glutaredoxin (thioltransferase)
GPSM2 G-protein signaling modulator 2
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
IGHM immunoglobulin heavy constant mu
INSIG2 insulin induced gene 2
IVD isovaleryl-CoA dehydrogenase
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KDM4A lysine (K)-specific demethylase 4A
KLHL25 kelch-like family member 25
LRRC42 leucine rich repeat containing 42
LUZP1 leucine zipper protein 1
MARK1 MAP/microtubule affinity-regulating kinase 1
MARK4 MAP/microtubule affinity-regulating kinase 4
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MT1G metallothionein 1G
MT1H metallothionein 1H
MTSS1 metastasis suppressor 1
N4BP1 NEDD4 binding protein 1
NEU3 sialidase 3 (membrane sialidase)
NTS neurotensin
NXN nucleoredoxin
PAPPA2 pappalysin 2
PCDH17 protocadherin 17
PELI1 pellino E3 ubiquitin protein ligase 1
PGF placental growth factor
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RAB1A RAB1A, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAI14 retinoic acid induced 14
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RBBP6 retinoblastoma binding protein 6
SCML2 sex comb on midleg-like 2 (Drosophila)
SCN10A sodium channel, voltage gated, type X alpha subunit
SEC14L1 SEC14-like 1 (S. cerevisiae)
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
SOX15 SRY (sex determining region Y)-box 15
SPAG9 sperm associated antigen 9
SPX spexin hormone
SREBF1 sterol regulatory element binding transcription factor 1
ST5 suppression of tumorigenicity 5
STC1 stanniocalcin 1
STK38L serine/threonine kinase 38 like
STX12 syntaxin 12
STX7 syntaxin 7
TBPL1 TBP-like 1
TBX6 T-box 6
TBXA2R thromboxane A2 receptor
TMEM161A transmembrane protein 161A
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNK2 tyrosine kinase, non-receptor, 2
TPPP tubulin polymerization promoting protein
TRIM33 tripartite motif containing 33
TTLL3 tubulin tyrosine ligase-like family member 3
USP15 ubiquitin specific peptidase 15
VAMP4 vesicle-associated membrane protein 4
XDH xanthine dehydrogenase
ZNHIT2 zinc finger, HIT-type containing 2

decreased expression

Symbol Name
ACTL6A actin-like 6A
ALPK1 alpha-kinase 1
ANKRD40 ankyrin repeat domain 40
ASB9 ankyrin repeat and SOCS box containing 9
B3GAT1 beta-1,3-glucuronyltransferase 1
BCAR3 breast cancer anti-estrogen resistance 3
BEST1 bestrophin 1
BFAR bifunctional apoptosis regulator
BRIX1 BRX1, biogenesis of ribosomes
C1ORF123 chromosome 1 open reading frame 123
C9ORF91 chromosome 9 open reading frame 91
CCDC94 coiled-coil domain containing 94
CD2BP2 CD2 (cytoplasmic tail) binding protein 2
CHKB choline kinase beta
CLCN5 chloride channel, voltage-sensitive 5
CLDN17 claudin 17
COMMD8 COMM domain containing 8
CSNK1D casein kinase 1, delta
DBF4B DBF4 zinc finger B
DERL2 derlin 2
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
DPP3 dipeptidyl-peptidase 3
EBAG9 estrogen receptor binding site associated, antigen, 9
ERCC2 excision repair cross-complementation group 2
ERF Ets2 repressor factor
ERI2 ERI1 exoribonuclease family member 2
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
ESRP1 epithelial splicing regulatory protein 1
GALNS galactosamine (N-acetyl)-6-sulfatase
GBAS glioblastoma amplified sequence
GBE1 glucan (1,4-alpha-), branching enzyme 1
GNL2 guanine nucleotide binding protein-like 2 (nucleolar)
GPATCH3 G patch domain containing 3
GPR143 G protein-coupled receptor 143
HAS2 hyaluronan synthase 2
HDAC5 histone deacetylase 5
HMGB2 high mobility group box 2
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H')
IRF9 interferon regulatory factor 9
KIAA0430 KIAA0430
KLHL21 kelch-like family member 21
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LHB luteinizing hormone beta polypeptide
LYPD1 LY6/PLAUR domain containing 1
MAGEA5 melanoma antigen family A5
MAPK6 mitogen-activated protein kinase 6
MED17 mediator complex subunit 17
MEPCE methylphosphate capping enzyme
MGA MGA, MAX dimerization protein
MON1B MON1 secretory trafficking family member B
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NCAPH non-SMC condensin I complex, subunit H
NCSTN nicastrin
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4
NEMF nuclear export mediator factor
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
OSGIN1 oxidative stress induced growth inhibitor 1
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PISD phosphatidylserine decarboxylase
PLCD1 phospholipase C, delta 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PMPCB peptidase (mitochondrial processing) beta
PNRC2 proline-rich nuclear receptor coactivator 2
POLE polymerase (DNA directed), epsilon, catalytic subunit
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRMT3 protein arginine methyltransferase 3
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
RNF144A ring finger protein 144A
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S1PR4 sphingosine-1-phosphate receptor 4
SARS2 seryl-tRNA synthetase 2, mitochondrial
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SGK2 serum/glucocorticoid regulated kinase 2
SHPK sedoheptulokinase
SLC5A4 solute carrier family 5 (glucose activated ion channel), member 4
SLMO2 slowmo homolog 2 (Drosophila)
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SMYD5 SMYD family member 5
SSNA1 Sjogren syndrome nuclear autoantigen 1
TAC3 tachykinin 3
TBCC tubulin folding cofactor C
THOC6 THO complex 6
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TNS3 tensin 3
TRAPPC12 trafficking protein particle complex 12
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
UEVLD UEV and lactate/malate dehyrogenase domains
UNC50 unc-50 homolog (C. elegans)
UNG uracil-DNA glycosylase
WDR46 WD repeat domain 46
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2
ZCCHC8 zinc finger, CCHC domain containing 8
ZNF143 zinc finger protein 143
ZNF146 zinc finger protein 146
ZZZ3 zinc finger, ZZ-type containing 3