valproic acid-6199 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the valproic acid-6199 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACP6 acid phosphatase 6, lysophosphatidic
ADGRL2 adhesion G protein-coupled receptor L2
AGFG2 ArfGAP with FG repeats 2
ANG angiogenin, ribonuclease, RNase A family, 5
ANKRD6 ankyrin repeat domain 6
AP3S2 adaptor-related protein complex 3, sigma 2 subunit
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APOL1 apolipoprotein L, 1
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
BACE1 beta-site APP-cleaving enzyme 1
BANK1 B-cell scaffold protein with ankyrin repeats 1
BIN1 bridging integrator 1
BTN2A3P butyrophilin, subfamily 2, member A3, pseudogene
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C5ORF45 chromosome 5 open reading frame 45
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CBR3 carbonyl reductase 3
CCNO cyclin O
CCSER2 coiled-coil serine-rich protein 2
CD34 CD34 molecule
CD59 CD59 molecule, complement regulatory protein
CDC14A cell division cycle 14A
CDC42 cell division cycle 42
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL6A1 collagen, type VI, alpha 1
CPM carboxypeptidase M
CSRP2 cysteine and glycine-rich protein 2
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTSZ cathepsin Z
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DNAAF1 dynein, axonemal, assembly factor 1
DSP desmoplakin
DVL2 dishevelled segment polarity protein 2
ECI2 enoyl-CoA delta isomerase 2
EFNA4 ephrin-A4
ETV1 ets variant 1
EXT1 exostosin glycosyltransferase 1
F11R F11 receptor
FAM110B family with sequence similarity 110, member B
FCAR Fc fragment of IgA receptor
FKBP9 FK506 binding protein 9, 63 kDa
FOXO1 forkhead box O1
FRS3 fibroblast growth factor receptor substrate 3
GLP1R glucagon-like peptide 1 receptor
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HPX hemopexin
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IQSEC1 IQ motif and Sec7 domain 1
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
KHK ketohexokinase (fructokinase)
KIAA0040 KIAA0040
KLHL3 kelch-like family member 3
LEF1 lymphoid enhancer-binding factor 1
LPAR1 lysophosphatidic acid receptor 1
LPCAT3 lysophosphatidylcholine acyltransferase 3
LPPR4 lipid phosphate phosphatase-related protein type 4
MARCKS myristoylated alanine-rich protein kinase C substrate
MCAM melanoma cell adhesion molecule
MCF2L MCF.2 cell line derived transforming sequence-like
MFAP3L microfibrillar-associated protein 3-like
MYO6 myosin VI
NCAM1 neural cell adhesion molecule 1
NEBL nebulette
NXPE3 neurexophilin and PC-esterase domain family, member 3
OGFR opioid growth factor receptor
OR10J1 olfactory receptor, family 10, subfamily J, member 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PCGF2 polycomb group ring finger 2
PCNXL2 pecanex-like 2 (Drosophila)
PDGFRL platelet-derived growth factor receptor-like
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PLS1 plastin 1
PORCN porcupine homolog (Drosophila)
POU2F3 POU class 2 homeobox 3
POU4F1 POU class 4 homeobox 1
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E
PPP1R26 protein phosphatase 1, regulatory subunit 26
RAB3D RAB3D, member RAS oncogene family
RPL13P5 ribosomal protein L13 pseudogene 5
SH3BP1 SH3-domain binding protein 1
SLITRK5 SLIT and NTRK-like family, member 5
SNCG synuclein, gamma (breast cancer-specific protein 1)
SP110 SP110 nuclear body protein
SPINT1 serine peptidase inhibitor, Kunitz type 1
ST5 suppression of tumorigenicity 5
STAP1 signal transducing adaptor family member 1
STON1 stonin 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRIM36 tripartite motif containing 36
TRIM9 tripartite motif containing 9
TSPAN13 tetraspanin 13
VENTX VENT homeobox
ZMIZ2 zinc finger, MIZ-type containing 2

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACP5 acid phosphatase 5, tartrate resistant
ACYP2 acylphosphatase 2, muscle type
ADI1 acireductone dioxygenase 1
ALPK1 alpha-kinase 1
ANKRD11 ankyrin repeat domain 11
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
APOBR apolipoprotein B receptor
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
AXIN1 axin 1
BBC3 BCL2 binding component 3
C17ORF70 chromosome 17 open reading frame 70
C2CD2 C2 calcium-dependent domain containing 2
C5AR1 complement component 5a receptor 1
C9ORF91 chromosome 9 open reading frame 91
CCL2 chemokine (C-C motif) ligand 2
CCL4 chemokine (C-C motif) ligand 4
CD101 CD101 molecule
CD14 CD14 molecule
CD1C CD1c molecule
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CLCN5 chloride channel, voltage-sensitive 5
COL9A2 collagen, type IX, alpha 2
COQ6 coenzyme Q6 monooxygenase
CUX2 cut-like homeobox 2
DCAF13 DDB1 and CUL4 associated factor 13
DEAF1 DEAF1 transcription factor
EXD3 exonuclease 3'-5' domain containing 3
FAM172A family with sequence similarity 172, member A
FBRS fibrosin
FBXO22 F-box protein 22
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HIST1H2BO histone cluster 1, H2bo
HIST2H2AA3 histone cluster 2, H2aa3
HP haptoglobin
IFI44L interferon-induced protein 44-like
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL1R2 interleukin 1 receptor, type II
IL24 interleukin 24
INHBE inhibin, beta E
ITFG2 integrin alpha FG-GAP repeat containing 2
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KLF11 Kruppel-like factor 11
KLF13 Kruppel-like factor 13
KLK5 kallikrein-related peptidase 5
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LMNB1 lamin B1
MBNL3 muscleblind-like splicing regulator 3
MCRS1 microspherule protein 1
MEGF8 multiple EGF-like-domains 8
METTL1 methyltransferase like 1
METTL16 methyltransferase like 16
MFSD12 major facilitator superfamily domain containing 12
MXD3 MAX dimerization protein 3
NARFL nuclear prelamin A recognition factor-like
NHEJ1 nonhomologous end-joining factor 1
NINJ2 ninjurin 2
NRBP1 nuclear receptor binding protein 1
NT5E 5'-nucleotidase, ecto (CD73)
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PNOC prepronociceptin
PPIEL peptidylprolyl isomerase E-like pseudogene
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRDM1 PR domain containing 1, with ZNF domain
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PTPRS protein tyrosine phosphatase, receptor type, S
PYGB phosphorylase, glycogen; brain
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RETN resistin
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLMO1 slowmo homolog 1 (Drosophila)
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SMYD5 SMYD family member 5
SNX16 sorting nexin 16
SPON2 spondin 2, extracellular matrix protein
SPP1 secreted phosphoprotein 1
SRD5A3 steroid 5 alpha-reductase 3
SREK1 splicing regulatory glutamine/lysine-rich protein 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TET3 tet methylcytosine dioxygenase 3
THRAP3 thyroid hormone receptor associated protein 3
TREM2 triggering receptor expressed on myeloid cells 2
TSPYL2 TSPY-like 2
TTC27 tetratricopeptide repeat domain 27
TUBGCP5 tubulin, gamma complex associated protein 5
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
VILL villin-like
VLDLR very low density lipoprotein receptor
XAB2 XPA binding protein 2
ZBTB3 zinc finger and BTB domain containing 3
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF219 zinc finger protein 219
ZNF787 zinc finger protein 787