valproic acid-6173 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the valproic acid-6173 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ABI2 abl-interactor 2
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1
AHI1 Abelson helper integration site 1
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
ARL15 ADP-ribosylation factor-like 15
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATN1 atrophin 1
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
BAIAP2 BAI1-associated protein 2
BICD1 bicaudal D homolog 1 (Drosophila)
BTNL3 butyrophilin-like 3
C3ORF18 chromosome 3 open reading frame 18
C7ORF69 chromosome 7 open reading frame 69
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CCDC170 coiled-coil domain containing 170
CCND1 cyclin D1
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CLIP2 CAP-GLY domain containing linker protein 2
COBLL1 cordon-bleu WH2 repeat protein-like 1
CSRP2 cysteine and glycine-rich protein 2
CTTN cortactin
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
EDDM3B epididymal protein 3B
EMID1 EMI domain containing 1
ESR1 estrogen receptor 1
FBXL18 F-box and leucine-rich repeat protein 18
FGFR2 fibroblast growth factor receptor 2
FLT3LG fms-related tyrosine kinase 3 ligand
FLT4 fms-related tyrosine kinase 4
FOXG1 forkhead box G1
GABARAPL3 GABA(A) receptors associated protein like 3, pseudogene
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10
GAS8 growth arrest-specific 8
GLRB glycine receptor, beta
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GP2 glycoprotein 2 (zymogen granule membrane)
GRK4 G protein-coupled receptor kinase 4
GYPA glycophorin A (MNS blood group)
HIF3A hypoxia inducible factor 3, alpha subunit
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IQSEC1 IQ motif and Sec7 domain 1
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KLHL35 kelch-like family member 35
KLHL36 kelch-like family member 36
LEFTY2 left-right determination factor 2
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4
LRP1 low density lipoprotein receptor-related protein 1
LTBP2 latent transforming growth factor beta binding protein 2
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MARCKS myristoylated alanine-rich protein kinase C substrate
MB myoglobin
MBOAT2 membrane bound O-acyltransferase domain containing 2
MCAM melanoma cell adhesion molecule
MST1L macrophage stimulating 1-like
MUC6 mucin 6, oligomeric mucus/gel-forming
MUC8 mucin 8
MYH10 myosin, heavy chain 10, non-muscle
MYO7A myosin VIIA
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NIPAL2 NIPA-like domain containing 2
NOD2 nucleotide-binding oligomerization domain containing 2
NPY6R neuropeptide Y receptor Y6 (pseudogene)
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OPRL1 opiate receptor-like 1
PADI2 peptidyl arginine deiminase, type II
PDE8B phosphodiesterase 8B
PDGFRL platelet-derived growth factor receptor-like
PLA2G3 phospholipase A2, group III
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLCH1 phospholipase C, eta 1
PLD1 phospholipase D1, phosphatidylcholine-specific
POU5F1P4 POU class 5 homeobox 1 pseudogene 4
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRB1 proline-rich protein BstNI subfamily 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
SAMD4A sterile alpha motif domain containing 4A
SIX3 SIX homeobox 3
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLITRK5 SLIT and NTRK-like family, member 5
ST14 suppression of tumorigenicity 14 (colon carcinoma)
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TEF thyrotrophic embryonic factor
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TRIM2 tripartite motif containing 2
TRIM62 tripartite motif containing 62
UST uronyl-2-sulfotransferase
ZFHX3 zinc finger homeobox 3
ZNF444 zinc finger protein 444
ZNF81 zinc finger protein 81
ZNF93 zinc finger protein 93

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADAM15 ADAM metallopeptidase domain 15
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AGPS alkylglycerone phosphate synthase
ANKFY1 ankyrin repeat and FYVE domain containing 1
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARRB1 arrestin, beta 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BOLA1 bolA family member 1
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
BSG basigin (Ok blood group)
C19ORF40 chromosome 19 open reading frame 40
C1ORF56 chromosome 1 open reading frame 56
C5ORF30 chromosome 5 open reading frame 30
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD14 CD14 molecule
CDC37 cell division cycle 37
CDK6 cyclin-dependent kinase 6
CLCN5 chloride channel, voltage-sensitive 5
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DGKE diacylglycerol kinase, epsilon 64kDa
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DOK3 docking protein 3
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ELP5 elongator acetyltransferase complex subunit 5
ERCC4 excision repair cross-complementation group 4
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EXOC5 exocyst complex component 5
FAM118A family with sequence similarity 118, member A
FAM204A family with sequence similarity 204, member A
FGGY FGGY carbohydrate kinase domain containing
FKBP5 FK506 binding protein 5
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GALK1 galactokinase 1
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GDE1 glycerophosphodiester phosphodiesterase 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GSDMD gasdermin D
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
GTF2I general transcription factor IIi
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
H2BFS H2B histone family, member S (pseudogene)
HIST1H2BH histone cluster 1, H2bh
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
INCENP inner centromere protein antigens 135/155kDa
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCTD20 potassium channel tetramerization domain containing 20
KPNA4 karyopherin alpha 4 (importin alpha 3)
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LIN7A lin-7 homolog A (C. elegans)
MBTPS2 membrane-bound transcription factor peptidase, site 2
MDM4 MDM4, p53 regulator
METTL16 methyltransferase like 16
MLYCD malonyl-CoA decarboxylase
MPDU1 mannose-P-dolichol utilization defect 1
NBEAL2 neurobeachin-like 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NINJ2 ninjurin 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PGM3 phosphoglucomutase 3
POM121 POM121 transmembrane nucleoporin
POMZP3 POM121 and ZP3 fusion
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PSAT1 phosphoserine aminotransferase 1
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
R3HCC1L R3H domain and coiled-coil containing 1-like
RFXAP regulatory factor X-associated protein
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF141 ring finger protein 141
RNF146 ring finger protein 146
RNFT1 ring finger protein, transmembrane 1
SCYL2 SCY1-like 2 (S. cerevisiae)
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10
SKA1 spindle and kinetochore associated complex subunit 1
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
STK4 serine/threonine kinase 4
TASP1 taspase, threonine aspartase, 1
TLR1 toll-like receptor 1
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM209 transmembrane protein 209
TMEM230 transmembrane protein 230
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TRIM25 tripartite motif containing 25
TTC26 tetratricopeptide repeat domain 26
TWISTNB TWIST neighbor
TXLNG taxilin gamma
UBE2S ubiquitin-conjugating enzyme E2S
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
ZFYVE21 zinc finger, FYVE domain containing 21
ZNF227 zinc finger protein 227
ZNF350 zinc finger protein 350
ZNF675 zinc finger protein 675
ZNF83 zinc finger protein 83
ZNHIT2 zinc finger, HIT-type containing 2