valproic acid-5219 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the valproic acid-5219 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACTN1 actinin, alpha 1
ADGRE5 adhesion G protein-coupled receptor E5
ADM adrenomedullin
APC adenomatous polyposis coli
APOLD1 apolipoprotein L domain containing 1
ARHGAP33 Rho GTPase activating protein 33
ARTN artemin
ASIC1 acid sensing (proton gated) ion channel 1
ASPH aspartate beta-hydroxylase
BBC3 BCL2 binding component 3
BBS9 Bardet-Biedl syndrome 9
C16ORF58 chromosome 16 open reading frame 58
C17ORF53 chromosome 17 open reading frame 53
C17ORF59 chromosome 17 open reading frame 59
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCPG1 cell cycle progression 1
CDON cell adhesion associated, oncogene regulated
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLCN7 chloride channel, voltage-sensitive 7
CLGN calmegin
CNPPD1 cyclin Pas1/PHO80 domain containing 1
CORO7 coronin 7
CRHR2 corticotropin releasing hormone receptor 2
CXCR4 chemokine (C-X-C motif) receptor 4
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DOK4 docking protein 4
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EPHA3 EPH receptor A3
ERN2 endoplasmic reticulum to nucleus signaling 2
FADS2 fatty acid desaturase 2
FBLN1 fibulin 1
FGD1 FYVE, RhoGEF and PH domain containing 1
FLJ22184
FN1 fibronectin 1
FOXN3 forkhead box N3
GFI1 growth factor independent 1 transcription repressor
GM2A GM2 ganglioside activator
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPR137 G protein-coupled receptor 137
GPR157 G protein-coupled receptor 157
HHAT hedgehog acyltransferase
HIST1H3E histone cluster 1, H3e
HRASLS HRAS-like suppressor
HRH2 histamine receptor H2
IFT27 intraflagellar transport 27
IL12RB1 interleukin 12 receptor, beta 1
IQCE IQ motif containing E
ITM2C integral membrane protein 2C
JAK2 Janus kinase 2
KIF13A kinesin family member 13A
KRT15 keratin 15, type I
LAMP1 lysosomal-associated membrane protein 1
LINC00652 long intergenic non-protein coding RNA 652
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MBD2 methyl-CpG binding domain protein 2
MED15 mediator complex subunit 15
MED9 mediator complex subunit 9
MTCP1 mature T-cell proliferation 1
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NOVA2 neuro-oncological ventral antigen 2
NT5DC3 5'-nucleotidase domain containing 3
OSGIN2 oxidative stress induced growth inhibitor family member 2
PAPPA2 pappalysin 2
PDCD6 programmed cell death 6
PKP2 plakophilin 2
POLL polymerase (DNA directed), lambda
POU2F2 POU class 2 homeobox 2
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PRDM1 PR domain containing 1, with ZNF domain
PRKCE protein kinase C, epsilon
RGS12 regulator of G-protein signaling 12
RPAIN RPA interacting protein
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
S100A13 S100 calcium binding protein A13
SH3D21 SH3 domain containing 21
SH3GL3 SH3-domain GRB2-like 3
SLC12A8 solute carrier family 12, member 8
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SNRK SNF related kinase
STXBP6 syntaxin binding protein 6 (amisyn)
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TBX3 T-box 3
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TTC9 tetratricopeptide repeat domain 9
TTLL4 tubulin tyrosine ligase-like family member 4
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
VPS9D1 VPS9 domain containing 1
WDR62 WD repeat domain 62
WIZ widely interspaced zinc finger motifs
WSB1 WD repeat and SOCS box containing 1
YY2 YY2 transcription factor
ZCCHC11 zinc finger, CCHC domain containing 11
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
ACTL8 actin-like 8
ACTN4 actinin, alpha 4
ALDOC aldolase C, fructose-bisphosphate
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ANKZF1 ankyrin repeat and zinc finger domain containing 1
APOD apolipoprotein D
ARPIN actin-related protein 2/3 complex inhibitor
ASCC2 activating signal cointegrator 1 complex subunit 2
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BAGE B melanoma antigen
BHLHE41 basic helix-loop-helix family, member e41
C16ORF45 chromosome 16 open reading frame 45
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CDK3 cyclin-dependent kinase 3
CNGB3 cyclic nucleotide gated channel beta 3
CORO1A coronin, actin binding protein, 1A
CORT cortistatin
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DACH1 dachshund family transcription factor 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DNASE1L1 deoxyribonuclease I-like 1
DOC2A double C2-like domains, alpha
DSCAM Down syndrome cell adhesion molecule
FAAH fatty acid amide hydrolase
GAMT guanidinoacetate N-methyltransferase
GEMIN8 gem (nuclear organelle) associated protein 8
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPR1 G protein-coupled receptor 1
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
HIST1H1E histone cluster 1, H1e
HIST1H2AJ histone cluster 1, H2aj
HIST1H4C histone cluster 1, H4c
HIST1H4D histone cluster 1, H4d
HIST1H4F histone cluster 1, H4f
HOXC13 homeobox C13
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IDI2-AS1 IDI2 antisense RNA 1
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL22 interleukin 22
INO80D INO80 complex subunit D
IQCG IQ motif containing G
IRF7 interferon regulatory factor 7
ISG15 ISG15 ubiquitin-like modifier
KIAA0894 KIAA0894 protein
KLF3 Kruppel-like factor 3 (basic)
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MBTD1 mbt domain containing 1
MDM4 MDM4, p53 regulator
METTL16 methyltransferase like 16
MOSPD3 motile sperm domain containing 3
MRPS18C mitochondrial ribosomal protein S18C
NOL12 nucleolar protein 12
NPM3 nucleophosmin/nucleoplasmin 3
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PRR4 proline rich 4 (lacrimal)
PTCD2 pentatricopeptide repeat domain 2
RBM41 RNA binding motif protein 41
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RHOG ras homolog family member G
RPL13P5 ribosomal protein L13 pseudogene 5
SEPP1 selenoprotein P, plasma, 1
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC35F5 solute carrier family 35, member F5
SLMO1 slowmo homolog 1 (Drosophila)
SP140L SP140 nuclear body protein-like
SPRY2 sprouty homolog 2 (Drosophila)
SPRYD7 SPRY domain containing 7
SSBP3 single stranded DNA binding protein 3
STARD13 StAR-related lipid transfer (START) domain containing 13
STRA6 stimulated by retinoic acid 6
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAOK1 TAO kinase 1
TBX19 T-box 19
TCTN2 tectonic family member 2
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TMEM180 transmembrane protein 180
TMEM212 transmembrane protein 212
TRIM25 tripartite motif containing 25
UNC119 unc-119 homolog (C. elegans)
VASH2 vasohibin 2
VAX2 ventral anterior homeobox 2
ZMAT5 zinc finger, matrin-type 5
ZNF124 zinc finger protein 124
ZNF195 zinc finger protein 195
ZNF205 zinc finger protein 205
ZNF286A zinc finger protein 286A
ZNF304 zinc finger protein 304
ZNF350 zinc finger protein 350
ZNF506 zinc finger protein 506
ZNF675 zinc finger protein 675