valproic acid-4464 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the valproic acid-4464 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACTN2 actinin, alpha 2
ADGRB2 adhesion G protein-coupled receptor B2
AIF1 allograft inflammatory factor 1
AKAP5 A kinase (PRKA) anchor protein 5
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ARC activity-regulated cytoskeleton-associated protein
ARTN artemin
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATHL1 ATH1, acid trehalase-like 1 (yeast)
BTG2 BTG family, member 2
BTN3A2 butyrophilin, subfamily 3, member A2
C14ORF1 chromosome 14 open reading frame 1
CBLC Cbl proto-oncogene C, E3 ubiquitin protein ligase
CD22 CD22 molecule
CDRT1 CMT1A duplicated region transcript 1
COL1A1 collagen, type I, alpha 1
COL4A6 collagen, type IV, alpha 6
CT62 cancer/testis antigen 62
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DFNB31 deafness, autosomal recessive 31
DKFZP434C153 DKFZP434C153 protein
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
EDRF1 erythroid differentiation regulatory factor 1
ELOVL4 ELOVL fatty acid elongase 4
EPOR erythropoietin receptor
EYA3 EYA transcriptional coactivator and phosphatase 3
FADS3 fatty acid desaturase 3
FAM131B family with sequence similarity 131, member B
FAS Fas cell surface death receptor
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FGF22 fibroblast growth factor 22
FOXO4 forkhead box O4
FYN FYN proto-oncogene, Src family tyrosine kinase
GABARAPL3 GABA(A) receptors associated protein like 3, pseudogene
GLI2 GLI family zinc finger 2
GLS2 glutaminase 2 (liver, mitochondrial)
GMPR guanosine monophosphate reductase
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GRK5 G protein-coupled receptor kinase 5
GYG2 glycogenin 2
HBB hemoglobin, beta
HHIPL2 HHIP-like 2
HLA-DOB major histocompatibility complex, class II, DO beta
ICAM1 intercellular adhesion molecule 1
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KLF13 Kruppel-like factor 13
LINC00312 long intergenic non-protein coding RNA 312
LINC00341 long intergenic non-protein coding RNA 341
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAPK11 mitogen-activated protein kinase 11
MBNL3 muscleblind-like splicing regulator 3
MIER2 mesoderm induction early response 1, family member 2
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
NDRG4 NDRG family member 4
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
OBSL1 obscurin-like 1
OXTR oxytocin receptor
PALM paralemmin
PDE5A phosphodiesterase 5A, cGMP-specific
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PRAF2 PRA1 domain family, member 2
PSD4 pleckstrin and Sec7 domain containing 4
PTCH1 patched 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPRU protein tyrosine phosphatase, receptor type, U
RAB36 RAB36, member RAS oncogene family
RGS4 regulator of G-protein signaling 4
RIN1 Ras and Rab interactor 1
S1PR1 sphingosine-1-phosphate receptor 1
SCAND2P SCAN domain containing 2 pseudogene
SCN11A sodium channel, voltage gated, type XI alpha subunit
SEPP1 selenoprotein P, plasma, 1
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SIX3 SIX homeobox 3
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC39A9 solute carrier family 39, member 9
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SYNGR3 synaptogyrin 3
SYT1 synaptotagmin I
SZT2 seizure threshold 2 homolog (mouse)
TBCD tubulin folding cofactor D
TFCP2L1 transcription factor CP2-like 1
TGFBR3 transforming growth factor, beta receptor III
TP53I11 tumor protein p53 inducible protein 11
TRIM15 tripartite motif containing 15
VAMP5 vesicle-associated membrane protein 5
VIPR1 vasoactive intestinal peptide receptor 1
ZNF204P zinc finger protein 204, pseudogene
ZNF343 zinc finger protein 343
ZNF507 zinc finger protein 507
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADCK4 aarF domain containing kinase 4
AIRE autoimmune regulator
ALPK1 alpha-kinase 1
ANKH ANKH inorganic pyrophosphate transport regulator
AOC2 amine oxidase, copper containing 2 (retina-specific)
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
C11ORF16 chromosome 11 open reading frame 16
C1ORF105 chromosome 1 open reading frame 105
C1QB complement component 1, q subcomponent, B chain
C5ORF45 chromosome 5 open reading frame 45
C8ORF60 chromosome 8 open reading frame 60
C9ORF9 chromosome 9 open reading frame 9
CARD8 caspase recruitment domain family, member 8
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CENPJ centromere protein J
CEP295 centrosomal protein 295kDa
CHM choroideremia (Rab escort protein 1)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLTCL1 clathrin, heavy chain-like 1
COG7 component of oligomeric golgi complex 7
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DBF4B DBF4 zinc finger B
DCBLD2 discoidin, CUB and LCCL domain containing 2
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DNM3 dynamin 3
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPX eosinophil peroxidase
FAM46C family with sequence similarity 46, member C
FAM63A family with sequence similarity 63, member A
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FLT4 fms-related tyrosine kinase 4
FOXN2 forkhead box N2
FRMD1 FERM domain containing 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GAN gigaxonin
GAS2 growth arrest-specific 2
GJA9 gap junction protein, alpha 9, 59kDa
GK3P glycerol kinase 3 pseudogene
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNG7 guanine nucleotide binding protein (G protein), gamma 7
HAL histidine ammonia-lyase
HIST1H1D histone cluster 1, H1d
HIST1H3A histone cluster 1, H3a
HIST1H4C histone cluster 1, H4c
HLA-DMB major histocompatibility complex, class II, DM beta
HOXA4 homeobox A4
IDI2-AS1 IDI2 antisense RNA 1
INPP5J inositol polyphosphate-5-phosphatase J
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KCTD17 potassium channel tetramerization domain containing 17
KLHL25 kelch-like family member 25
KRT32 keratin 32, type I
KRT86 keratin 86, type II
LRP2 low density lipoprotein receptor-related protein 2
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MMP2 matrix metallopeptidase 2
MNX1 motor neuron and pancreas homeobox 1
MRAS muscle RAS oncogene homolog
MTA2 metastasis associated 1 family, member 2
NEUROD4 neuronal differentiation 4
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NIPAL2 NIPA-like domain containing 2
NIPSNAP3B nipsnap homolog 3B (C. elegans)
NOL12 nucleolar protein 12
NT5M 5',3'-nucleotidase, mitochondrial
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PADI2 peptidyl arginine deiminase, type II
PENK proenkephalin
PLSCR2 phospholipid scramblase 2
POU3F2 POU class 3 homeobox 2
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PRR14L proline rich 14-like
PTCD2 pentatricopeptide repeat domain 2
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RNF126P1 ring finger protein 126 pseudogene 1
RPL10L ribosomal protein L10-like
RUNX1-IT1 RUNX1 intronic transcript 1
SCGB2A2 secretoglobin, family 2A, member 2
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SRD5A3 steroid 5 alpha-reductase 3
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
UPK3B uroplakin 3B
WNT16 wingless-type MMTV integration site family, member 16
YY2 YY2 transcription factor
ZNF155 zinc finger protein 155
ZNF280B zinc finger protein 280B