valproic acid-409 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the valproic acid-409 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
ASCL1 achaete-scute family bHLH transcription factor 1
ATXN7L3B ataxin 7-like 3B
BATF3 basic leucine zipper transcription factor, ATF-like 3
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BST2 bone marrow stromal cell antigen 2
C10ORF76 chromosome 10 open reading frame 76
C16ORF58 chromosome 16 open reading frame 58
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C2CD2L C2CD2-like
C6ORF106 chromosome 6 open reading frame 106
CAMLG calcium modulating ligand
CANT1 calcium activated nucleotidase 1
CAPN10 calpain 10
CCNG2 cyclin G2
CCSER2 coiled-coil serine-rich protein 2
CD2AP CD2-associated protein
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
CLCN3 chloride channel, voltage-sensitive 3
CREB3 cAMP responsive element binding protein 3
CTNNBIP1 catenin, beta interacting protein 1
DDAH2 dimethylarginine dimethylaminohydrolase 2
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10
DUS2 dihydrouridine synthase 2
ECI2 enoyl-CoA delta isomerase 2
EMC1 ER membrane protein complex subunit 1
EPOR erythropoietin receptor
FAM65A family with sequence similarity 65, member A
FANCF Fanconi anemia, complementation group F
FKBP8 FK506 binding protein 8, 38kDa
FYN FYN proto-oncogene, Src family tyrosine kinase
GBAP1 glucosidase, beta, acid pseudogene 1
GJB3 gap junction protein, beta 3, 31kDa
GK glycerol kinase
GM2A GM2 ganglioside activator
GNB5 guanine nucleotide binding protein (G protein), beta 5
GPR65 G protein-coupled receptor 65
GRIK5 glutamate receptor, ionotropic, kainate 5
GSK3A glycogen synthase kinase 3 alpha
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa
IFI16 interferon, gamma-inducible protein 16
IGF1 insulin-like growth factor 1 (somatomedin C)
IRGQ immunity-related GTPase family, Q
JUP junction plakoglobin
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1
KIF21B kinesin family member 21B
KIF5C kinesin family member 5C
LGALS8 lectin, galactoside-binding, soluble, 8
LMAN2L lectin, mannose-binding 2-like
LONP2 lon peptidase 2, peroxisomal
LPPR2 lipid phosphate phosphatase-related protein type 2
MAPK9 mitogen-activated protein kinase 9
MARCKS myristoylated alanine-rich protein kinase C substrate
MFSD12 major facilitator superfamily domain containing 12
MPV17 MpV17 mitochondrial inner membrane protein
MVK mevalonate kinase
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NCOA1 nuclear receptor coactivator 1
NF1 neurofibromin 1
NRGN neurogranin (protein kinase C substrate, RC3)
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PEX14 peroxisomal biogenesis factor 14
PLCL2 phospholipase C-like 2
PLD3 phospholipase D family, member 3
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
POMT1 protein-O-mannosyltransferase 1
POR P450 (cytochrome) oxidoreductase
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PTN pleiotrophin
PTTG3P pituitary tumor-transforming 3, pseudogene
RAB33B RAB33B, member RAS oncogene family
RAB8B RAB8B, member RAS oncogene family
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RNF144A ring finger protein 144A
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SDHAF1 succinate dehydrogenase complex assembly factor 1
SEZ6L seizure related 6 homolog (mouse)-like
SIDT2 SID1 transmembrane family, member 2
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SPINT1 serine peptidase inhibitor, Kunitz type 1
SRPK2 SRSF protein kinase 2
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
TM7SF2 transmembrane 7 superfamily member 2
TMEM127 transmembrane protein 127
TMEM184B transmembrane protein 184B
TPD52L1 tumor protein D52-like 1
TSPAN13 tetraspanin 13
TSPYL2 TSPY-like 2
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
ZC2HC1A zinc finger, C2HC-type containing 1A
ZEB1 zinc finger E-box binding homeobox 1
ZNF211 zinc finger protein 211

decreased expression

Symbol Name
ACP5 acid phosphatase 5, tartrate resistant
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6
AGMAT agmatine ureohydrolase (agmatinase)
AHSP alpha hemoglobin stabilizing protein
APOL6 apolipoprotein L, 6
ARMC6 armadillo repeat containing 6
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
AVEN apoptosis, caspase activation inhibitor
C19ORF57 chromosome 19 open reading frame 57
C1R complement component 1, r subcomponent
C2 complement component 2
C22ORF29 chromosome 22 open reading frame 29
C7ORF43 chromosome 7 open reading frame 43
CAMKV CaM kinase-like vesicle-associated
CCDC85C coiled-coil domain containing 85C
CD5 CD5 molecule
CFAP70 cilia and flagella associated protein 70
CLEC1B C-type lectin domain family 1, member B
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CST8 cystatin 8 (cystatin-related epididymal specific)
CXORF21 chromosome X open reading frame 21
DENND4C DENN/MADD domain containing 4C
DOC2A double C2-like domains, alpha
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
ECE2 endothelin converting enzyme 2
ECSIT ECSIT signalling integrator
ELP3 elongator acetyltransferase complex subunit 3
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FGFBP1 fibroblast growth factor binding protein 1
FHIT fragile histidine triad
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GRIA4 glutamate receptor, ionotropic, AMPA 4
GTF2I general transcription factor IIi
GUCA2A guanylate cyclase activator 2A (guanylin)
HAMP hepcidin antimicrobial peptide
HDAC5 histone deacetylase 5
HOXC6 homeobox C6
HSPB3 heat shock 27kDa protein 3
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
IL19 interleukin 19
IL22RA1 interleukin 22 receptor, alpha 1
INHA inhibin, alpha
IRS4 insulin receptor substrate 4
ITGA8 integrin, alpha 8
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KLK11 kallikrein-related peptidase 11
KRI1 KRI1 homolog (S. cerevisiae)
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LEFTY1 left-right determination factor 1
LENEP lens epithelial protein
LMCD1 LIM and cysteine-rich domains 1
LMNB1 lamin B1
LOC100129361
LPAR3 lysophosphatidic acid receptor 3
MILR1 mast cell immunoglobulin-like receptor 1
MRPL12 mitochondrial ribosomal protein L12
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MXRA5 matrix-remodelling associated 5
MYC v-myc avian myelocytomatosis viral oncogene homolog
NRSN2 neurensin 2
OMG oligodendrocyte myelin glycoprotein
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PADI1 peptidyl arginine deiminase, type I
PAX1 paired box 1
PCOLCE2 procollagen C-endopeptidase enhancer 2
PEF1 penta-EF-hand domain containing 1
PROL1 proline rich, lacrimal 1
PSG11 pregnancy specific beta-1-glycoprotein 11
PTPRN protein tyrosine phosphatase, receptor type, N
PTPRT protein tyrosine phosphatase, receptor type, T
RABL3 RAB, member of RAS oncogene family-like 3
RASAL1 RAS protein activator like 1 (GAP1 like)
RASL12 RAS-like, family 12
RBM14 RNA binding motif protein 14
RCAN2 regulator of calcineurin 2
RNF121 ring finger protein 121
RNF220 ring finger protein 220
SH2D4A SH2 domain containing 4A
SH3BP1 SH3-domain binding protein 1
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SNHG3 small nucleolar RNA host gene 3
T T, brachyury homolog (mouse)
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TGM5 transglutaminase 5
TMEM143 transmembrane protein 143
TMEM242 transmembrane protein 242
TMEM51 transmembrane protein 51
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TPM3 tropomyosin 3
TTC27 tetratricopeptide repeat domain 27
UBXN8 UBX domain protein 8
VEZT vezatin, adherens junctions transmembrane protein
VWF von Willebrand factor
WDR43 WD repeat domain 43
ZBTB38 zinc finger and BTB domain containing 38
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF408 zinc finger protein 408
ZNF778 zinc finger protein 778
ZPBP zona pellucida binding protein