valproic acid-347 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the valproic acid-347 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
AMT aminomethyltransferase
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
BAIAP2 BAI1-associated protein 2
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CAPN10 calpain 10
CASP10 caspase 10, apoptosis-related cysteine peptidase
CC2D1A coiled-coil and C2 domain containing 1A
CCDC85C coiled-coil domain containing 85C
CD177 CD177 molecule
CD93 CD93 molecule
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEP250 centrosomal protein 250kDa
CFAP70 cilia and flagella associated protein 70
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
COL6A1 collagen, type VI, alpha 1
COPZ2 coatomer protein complex, subunit zeta 2
CORO1A coronin, actin binding protein, 1A
CPNE7 copine VII
DTX4 deltex 4, E3 ubiquitin ligase
DXO decapping exoribonuclease
ELL elongation factor RNA polymerase II
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM50B family with sequence similarity 50, member B
FAM89B family with sequence similarity 89, member B
FANCA Fanconi anemia, complementation group A
FGFR1 fibroblast growth factor receptor 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GLS2 glutaminase 2 (liver, mitochondrial)
GRIK5 glutamate receptor, ionotropic, kainate 5
HAO2 hydroxyacid oxidase 2 (long chain)
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
ICAM1 intercellular adhesion molecule 1
IGF1 insulin-like growth factor 1 (somatomedin C)
INE1 inactivation escape 1 (non-protein coding)
INPP5J inositol polyphosphate-5-phosphatase J
JAKMIP2 janus kinase and microtubule interacting protein 2
KREMEN2 kringle containing transmembrane protein 2
LAMC2 laminin, gamma 2
LARP7 La ribonucleoprotein domain family, member 7
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
MAP2K4 mitogen-activated protein kinase kinase 4
MFGE8 milk fat globule-EGF factor 8 protein
MST1R macrophage stimulating 1 receptor
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MVK mevalonate kinase
MXRA5 matrix-remodelling associated 5
MYL4 myosin, light chain 4, alkali; atrial, embryonic
N4BP2L2 NEDD4 binding protein 2-like 2
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit
NOP16 NOP16 nucleolar protein
NRP2 neuropilin 2
OASL 2'-5'-oligoadenylate synthetase-like
PCDH11Y protocadherin 11 Y-linked
PCP4 Purkinje cell protein 4
PIGR polymeric immunoglobulin receptor
PIGV phosphatidylinositol glycan anchor biosynthesis, class V
PLEK pleckstrin
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme
PRELP proline/arginine-rich end leucine-rich repeat protein
PXDC1 PX domain containing 1
RAB29 RAB29, member RAS oncogene family
RAB8B RAB8B, member RAS oncogene family
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
RIPK4 receptor-interacting serine-threonine kinase 4
RRBP1 ribosome binding protein 1
S100A1 S100 calcium binding protein A1
S1PR4 sphingosine-1-phosphate receptor 4
SERINC5 serine incorporator 5
SEZ6L seizure related 6 homolog (mouse)-like
SFXN3 sideroflexin 3
SGSH N-sulfoglucosamine sulfohydrolase
SH2D1A SH2 domain containing 1A
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SNX19 sorting nexin 19
SPON2 spondin 2, extracellular matrix protein
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
SYT17 synaptotagmin XVII
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMEM121 transmembrane protein 121
TMEM159 transmembrane protein 159
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TNK1 tyrosine kinase, non-receptor, 1
TSPAN7 tetraspanin 7
UBE4B ubiquitination factor E4B
WDR46 WD repeat domain 46
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
ZNF277 zinc finger protein 277
ZNF394 zinc finger protein 394
ZNF446 zinc finger protein 446
ZNF771 zinc finger protein 771

decreased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ADGRG3 adhesion G protein-coupled receptor G3
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
APOH apolipoprotein H (beta-2-glycoprotein I)
AQP8 aquaporin 8
ARMC7 armadillo repeat containing 7
ARSF arylsulfatase F
BAGE B melanoma antigen
BATF3 basic leucine zipper transcription factor, ATF-like 3
C4BPA complement component 4 binding protein, alpha
CARTPT CART prepropeptide
CAV3 caveolin 3
CCDC176 coiled-coil domain containing 176
CCL19 chemokine (C-C motif) ligand 19
CCL22 chemokine (C-C motif) ligand 22
CD5 CD5 molecule
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLCF1 cardiotrophin-like cytokine factor 1
CSAD cysteine sulfinic acid decarboxylase
DGAT1 diacylglycerol O-acyltransferase 1
DSP desmoplakin
EFCAB1 EF-hand calcium binding domain 1
EGFL7 EGF-like-domain, multiple 7
ELAVL4 ELAV like neuron-specific RNA binding protein 4
ELP6 elongator acetyltransferase complex subunit 6
FAM110D family with sequence similarity 110, member D
FAM153A family with sequence similarity 153, member A
FKBP10 FK506 binding protein 10, 65 kDa
FOSL1 FOS-like antigen 1
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FXYD6 FXYD domain containing ion transport regulator 6
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GADD45G growth arrest and DNA-damage-inducible, gamma
HDAC11 histone deacetylase 11
HIRIP3 HIRA interacting protein 3
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HPGDS hematopoietic prostaglandin D synthase
IL15RA interleukin 15 receptor, alpha
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
KCNK15 potassium channel, two pore domain subfamily K, member 15
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIF18A kinesin family member 18A
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KLHL3 kelch-like family member 3
KRI1 KRI1 homolog (S. cerevisiae)
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAGEB2 melanoma antigen family B2
MEPE matrix extracellular phosphoglycoprotein
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MOB3B MOB kinase activator 3B
MON1B MON1 secretory trafficking family member B
MTCP1 mature T-cell proliferation 1
NOL10 nucleolar protein 10
OR52A1 olfactory receptor, family 52, subfamily A, member 1
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAK1IP1 PAK1 interacting protein 1
PAN2 PAN2 poly(A) specific ribonuclease subunit
PCBP4 poly(rC) binding protein 4
PDE12 phosphodiesterase 12
PFAS phosphoribosylformylglycinamidine synthase
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PISD phosphatidylserine decarboxylase
PLCD1 phospholipase C, delta 1
POGLUT1 protein O-glucosyltransferase 1
PPCDC phosphopantothenoylcysteine decarboxylase
PPEF1 protein phosphatase, EF-hand calcium binding domain 1
PQLC3 PQ loop repeat containing 3
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
REC8 REC8 meiotic recombination protein
RHOH ras homolog family member H
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
SAG S-antigen; retina and pineal gland (arrestin)
SETD1A SET domain containing 1A
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMYD5 SMYD family member 5
SOAT2 sterol O-acyltransferase 2
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SSTR4 somatostatin receptor 4
STAB2 stabilin 2
TCEA2 transcription elongation factor A (SII), 2
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TDRD12 tudor domain containing 12
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM39B transmembrane protein 39B
TNNI3 troponin I type 3 (cardiac)
TREM1 triggering receptor expressed on myeloid cells 1
TTC27 tetratricopeptide repeat domain 27
TTI1 TELO2 interacting protein 1
TYR tyrosinase
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
VPREB3 pre-B lymphocyte 3
VTCN1 V-set domain containing T cell activation inhibitor 1
WDR13 WD repeat domain 13
XYLT1 xylosyltransferase I
ZXDC ZXD family zinc finger C