valproic acid-2682 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the valproic acid-2682 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ATN1 atrophin 1
ATXN2L ataxin 2-like
BCAS3 breast carcinoma amplified sequence 3
BTN3A1 butyrophilin, subfamily 3, member A1
C1ORF61 chromosome 1 open reading frame 61
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CCDC57 coiled-coil domain containing 57
CD300C CD300c molecule
CDO1 cysteine dioxygenase type 1
CDRT1 CMT1A duplicated region transcript 1
CENPO centromere protein O
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLGN calmegin
CNTNAP2 contactin associated protein-like 2
CREM cAMP responsive element modulator
CYHR1 cysteine/histidine-rich 1
DAPK2 death-associated protein kinase 2
DCAF4 DDB1 and CUL4 associated factor 4
DGKG diacylglycerol kinase, gamma 90kDa
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DPY19L1P1 DPY19L1 pseudogene 1
DSC3 desmocollin 3
DTNA dystrobrevin, alpha
EPHB3 EPH receptor B3
EVI5 ecotropic viral integration site 5
FAM212B family with sequence similarity 212, member B
FGF4 fibroblast growth factor 4
FHL1 four and a half LIM domains 1
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GLRX3 glutaredoxin 3
GSPT1 G1 to S phase transition 1
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HGD homogentisate 1,2-dioxygenase
HIST1H4D histone cluster 1, H4d
HMOX2 heme oxygenase 2
HOXA10 homeobox A10
HRH1 histamine receptor H1
HSPA2 heat shock 70kDa protein 2
ICOSLG inducible T-cell co-stimulator ligand
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IGL immunoglobulin lambda locus
IL10 interleukin 10
ISG20 interferon stimulated exonuclease gene 20kDa
IZUMO4 IZUMO family member 4
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KMT2A lysine (K)-specific methyltransferase 2A
KRT18 keratin 18, type I
LDLR low density lipoprotein receptor
LPIN1 lipin 1
MAP6D1 MAP6 domain containing 1
MAST2 microtubule associated serine/threonine kinase 2
MCM3AP minichromosome maintenance complex component 3 associated protein
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MTUS1 microtubule associated tumor suppressor 1
MUC6 mucin 6, oligomeric mucus/gel-forming
MYO3A myosin IIIA
MYO9B myosin IXB
NEBL nebulette
NR2F2 nuclear receptor subfamily 2, group F, member 2
OAZ3 ornithine decarboxylase antizyme 3
OMG oligodendrocyte myelin glycoprotein
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PCNXL2 pecanex-like 2 (Drosophila)
PKP3 plakophilin 3
PLA2G3 phospholipase A2, group III
PLCE1 phospholipase C, epsilon 1
PLCG1 phospholipase C, gamma 1
PROL1 proline rich, lacrimal 1
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PTCRA pre T-cell antigen receptor alpha
PTMS parathymosin
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RBPMS RNA binding protein with multiple splicing
RECQL5 RecQ protein-like 5
RFPL3S RFPL3 antisense
RIMS2 regulating synaptic membrane exocytosis 2
RND1 Rho family GTPase 1
S100A5 S100 calcium binding protein A5
SALL1 spalt-like transcription factor 1
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC48A1 solute carrier family 48 (heme transporter), member 1
SMC1A structural maintenance of chromosomes 1A
SNPH syntaphilin
SRRM2 serine/arginine repetitive matrix 2
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TAS2R4 taste receptor, type 2, member 4
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
THTPA thiamine triphosphatase
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1
TMEM63A transmembrane protein 63A
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TRPS1 trichorhinophalangeal syndrome I
TUBA4B tubulin, alpha 4b
TUBB2A tubulin, beta 2A class IIa
ZNF34 zinc finger protein 34
ZNF768 zinc finger protein 768

decreased expression

Symbol Name
ADAM2 ADAM metallopeptidase domain 2
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADGB androglobin
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2
APOC4 apolipoprotein C-IV
ARMCX4 armadillo repeat containing, X-linked 4
BTF3P12 basic transcription factor 3 pseudogene 12
C5AR1 complement component 5a receptor 1
C7ORF69 chromosome 7 open reading frame 69
CCDC92 coiled-coil domain containing 92
CCL27 chemokine (C-C motif) ligand 27
CCRL2 chemokine (C-C motif) receptor-like 2
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD79B CD79b molecule, immunoglobulin-associated beta
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CGA glycoprotein hormones, alpha polypeptide
CLEC2D C-type lectin domain family 2, member D
CTNNBIP1 catenin, beta interacting protein 1
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DSPP dentin sialophosphoprotein
DZANK1 double zinc ribbon and ankyrin repeat domains 1
ERCC6 excision repair cross-complementation group 6
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM120C family with sequence similarity 120C
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FRMPD1 FERM and PDZ domain containing 1
GIF gastric intrinsic factor (vitamin B synthesis)
GIPC1 GIPC PDZ domain containing family, member 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GPR3 G protein-coupled receptor 3
GRB7 growth factor receptor-bound protein 7
HAMP hepcidin antimicrobial peptide
HIST1H1E histone cluster 1, H1e
HIST1H2AE histone cluster 1, H2ae
HIST1H2AJ histone cluster 1, H2aj
HIST1H2AM histone cluster 1, H2am
HIST1H2BH histone cluster 1, H2bh
HIST1H2BN histone cluster 1, H2bn
HIST1H3B histone cluster 1, H3b
HIST1H3G histone cluster 1, H3g
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HP haptoglobin
HPSE heparanase
HRH2 histamine receptor H2
IFNA14 interferon, alpha 14
IFT140 intraflagellar transport 140
IL2 interleukin 2
KDM8 lysine (K)-specific demethylase 8
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KLF1 Kruppel-like factor 1 (erythroid)
KLHL36 kelch-like family member 36
KLK5 kallikrein-related peptidase 5
KRT81 keratin 81, type II
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LIME1 Lck interacting transmembrane adaptor 1
LONRF3 LON peptidase N-terminal domain and ring finger 3
LY6D lymphocyte antigen 6 complex, locus D
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MTMR12 myotubularin related protein 12
MTSS1L metastasis suppressor 1-like
MXD3 MAX dimerization protein 3
NAG18 NAG18 mRNA
NLGN1 neuroligin 1
NXF2 nuclear RNA export factor 2
OVGP1 oviductal glycoprotein 1, 120kDa
PKD2L2 polycystic kidney disease 2-like 2
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
POTEKP POTE ankyrin domain family, member K, pseudogene
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRDM12 PR domain containing 12
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SIPA1 signal-induced proliferation-associated 1
SLC16A6 solute carrier family 16, member 6
SLC22A14 solute carrier family 22, member 14
SYTL2 synaptotagmin-like 2
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TAGLN transgelin
TAS2R10 taste receptor, type 2, member 10
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
THRAP3 thyroid hormone receptor associated protein 3
TM7SF2 transmembrane 7 superfamily member 2
TMEM212 transmembrane protein 212
TMOD3 tropomodulin 3 (ubiquitous)
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNS2 tensin 2
TPM3 tropomyosin 3
TSC22D4 TSC22 domain family, member 4
UPK3A uroplakin 3A
ZC2HC1A zinc finger, C2HC-type containing 1A
ZNF10 zinc finger protein 10
ZNF552 zinc finger protein 552