valproic acid-2669 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the valproic acid-2669 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ABHD8 abhydrolase domain containing 8
ACP6 acid phosphatase 6, lysophosphatidic
ACSL6 acyl-CoA synthetase long-chain family member 6
ADGRL2 adhesion G protein-coupled receptor L2
AGFG2 ArfGAP with FG repeats 2
AMIGO2 adhesion molecule with Ig-like domain 2
ANG angiogenin, ribonuclease, RNase A family, 5
ARG2 arginase 2
ARL4C ADP-ribosylation factor-like 4C
ARMC9 armadillo repeat containing 9
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
BIK BCL2-interacting killer (apoptosis-inducing)
C17ORF59 chromosome 17 open reading frame 59
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CD59 CD59 molecule, complement regulatory protein
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
CEP70 centrosomal protein 70kDa
CPM carboxypeptidase M
CREB3 cAMP responsive element binding protein 3
CREB3L1 cAMP responsive element binding protein 3-like 1
DDAH2 dimethylarginine dimethylaminohydrolase 2
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DOCK4 dedicator of cytokinesis 4
DSP desmoplakin
DUSP4 dual specificity phosphatase 4
EFNA4 ephrin-A4
EPAS1 endothelial PAS domain protein 1
F11R F11 receptor
FAM49A family with sequence similarity 49, member A
FOXD1 forkhead box D1
GCH1 GTP cyclohydrolase 1
GIPR gastric inhibitory polypeptide receptor
GLRA2 glycine receptor, alpha 2
GMPR guanosine monophosphate reductase
GSN gelsolin
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13
KCTD20 potassium channel tetramerization domain containing 20
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1
KIF5C kinesin family member 5C
LPAR6 lysophosphatidic acid receptor 6
MAMLD1 mastermind-like domain containing 1
MAN1A1 mannosidase, alpha, class 1A, member 1
MARCKS myristoylated alanine-rich protein kinase C substrate
MBNL2 muscleblind-like splicing regulator 2
MEF2C myocyte enhancer factor 2C
MPZL1 myelin protein zero-like 1
MTSS1 metastasis suppressor 1
MTUS1 microtubule associated tumor suppressor 1
MVP major vault protein
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NCAM1 neural cell adhesion molecule 1
NDNF neuron-derived neurotrophic factor
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDH9 protocadherin 9
PCNXL2 pecanex-like 2 (Drosophila)
PDE4DIP phosphodiesterase 4D interacting protein
PDLIM5 PDZ and LIM domain 5
PFN2 profilin 2
PHTF2 putative homeodomain transcription factor 2
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLS1 plastin 1
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
POU4F1 POU class 4 homeobox 1
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAB26 RAB26, member RAS oncogene family
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RIMS3 regulating synaptic membrane exocytosis 3
RNASE4 ribonuclease, RNase A family, 4
RPGRIP1L RPGRIP1-like
SCML1 sex comb on midleg-like 1 (Drosophila)
SGCE sarcoglycan, epsilon
SGMS1 sphingomyelin synthase 1
SPRR2B small proline-rich protein 2B
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STON1 stonin 1
STXBP1 syntaxin binding protein 1
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TESK1 testis-specific kinase 1
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TPST1 tyrosylprotein sulfotransferase 1
TRPS1 trichorhinophalangeal syndrome I
TSPAN13 tetraspanin 13
TUBB2A tubulin, beta 2A class IIa
TUFT1 tuftelin 1
ULBP2 UL16 binding protein 2
USP6NL USP6 N-terminal like
WDR19 WD repeat domain 19
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZNF174 zinc finger protein 174

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ADGB androglobin
ANKRD40 ankyrin repeat domain 40
ANKRD55 ankyrin repeat domain 55
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARG1 arginase 1
BAHCC1 BAH domain and coiled-coil containing 1
C17ORF70 chromosome 17 open reading frame 70
C7ORF69 chromosome 7 open reading frame 69
C8A complement component 8, alpha polypeptide
CCDC94 coiled-coil domain containing 94
CCL2 chemokine (C-C motif) ligand 2
CCRL2 chemokine (C-C motif) receptor-like 2
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CHKB choline kinase beta
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CLCF1 cardiotrophin-like cytokine factor 1
COL4A2 collagen, type IV, alpha 2
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CXORF21 chromosome X open reading frame 21
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
DPEP2 dipeptidase 2
ECHDC2 enoyl CoA hydratase domain containing 2
ECSIT ECSIT signalling integrator
ENO3 enolase 3 (beta, muscle)
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
ERCC6 excision repair cross-complementation group 6
FANCC Fanconi anemia, complementation group C
FBRS fibrosin
FBXL2 F-box and leucine-rich repeat protein 2
FGR FGR proto-oncogene, Src family tyrosine kinase
FLT4 fms-related tyrosine kinase 4
FRS3 fibroblast growth factor receptor substrate 3
GRAMD1B GRAM domain containing 1B
HCFC1 host cell factor C1
HIST1H2AI histone cluster 1, H2ai
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BI histone cluster 1, H2bi
HSPA1L heat shock 70kDa protein 1-like
IFNA14 interferon, alpha 14
IL17RA interleukin 17 receptor A
IL1R2 interleukin 1 receptor, type II
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IRF7 interferon regulatory factor 7
ITFG2 integrin alpha FG-GAP repeat containing 2
JMJD4 jumonji domain containing 4
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KEAP1 kelch-like ECH-associated protein 1
KLHL21 kelch-like family member 21
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LTB lymphotoxin beta (TNF superfamily, member 3)
LY6D lymphocyte antigen 6 complex, locus D
MEPCE methylphosphate capping enzyme
METTL1 methyltransferase like 1
MFSD11 major facilitator superfamily domain containing 11
MILR1 mast cell immunoglobulin-like receptor 1
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NSD1 nuclear receptor binding SET domain protein 1
NXF2 nuclear RNA export factor 2
OCLN occludin
PEF1 penta-EF-hand domain containing 1
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRF1 perforin 1 (pore forming protein)
PRR4 proline rich 4 (lacrimal)
PTPN7 protein tyrosine phosphatase, non-receptor type 7
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF122 ring finger protein 122
SARS2 seryl-tRNA synthetase 2, mitochondrial
SIK1 salt-inducible kinase 1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SMYD5 SMYD family member 5
SRD5A3 steroid 5 alpha-reductase 3
STAT5A signal transducer and activator of transcription 5A
SYTL2 synaptotagmin-like 2
TAOK1 TAO kinase 1
TARP TCR gamma alternate reading frame protein
TBXAS1 thromboxane A synthase 1 (platelet)
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TERT telomerase reverse transcriptase
THBS4 thrombospondin 4
TMED1 transmembrane emp24 protein transport domain containing 1
TMEM53 transmembrane protein 53
TPM3 tropomyosin 3
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TRPV6 transient receptor potential cation channel, subfamily V, member 6
UNC93B1 unc-93 homolog B1 (C. elegans)
UPB1 ureidopropionase, beta
WDR6 WD repeat domain 6
WNT10B wingless-type MMTV integration site family, member 10B
XKR8 XK, Kell blood group complex subunit-related family, member 8
ZBED1 zinc finger, BED-type containing 1
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF408 zinc finger protein 408
ZNF428 zinc finger protein 428
ZNF76 zinc finger protein 76