valproic acid-1665 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the valproic acid-1665 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ANKRD26 ankyrin repeat domain 26
ARF6 ADP-ribosylation factor 6
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASPHD1 aspartate beta-hydroxylase domain containing 1
BEX4 brain expressed, X-linked 4
BLVRA biliverdin reductase A
C19ORF66 chromosome 19 open reading frame 66
CA11 carbonic anhydrase XI
CASKIN2 CASK interacting protein 2
CCDC28B coiled-coil domain containing 28B
CDH8 cadherin 8, type 2
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEMIP cell migration inducing protein, hyaluronan binding
CFAP70 cilia and flagella associated protein 70
CRTC1 CREB regulated transcription coactivator 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DGKE diacylglycerol kinase, epsilon 64kDa
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
EFNB3 ephrin-B3
EGFR epidermal growth factor receptor
EPOR erythropoietin receptor
EXTL3 exostosin-like glycosyltransferase 3
FA2H fatty acid 2-hydroxylase
FAM174B family with sequence similarity 174, member B
FER fer (fps/fes related) tyrosine kinase
FGD1 FYVE, RhoGEF and PH domain containing 1
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GADD45G growth arrest and DNA-damage-inducible, gamma
GLRX glutaredoxin (thioltransferase)
GM2A GM2 ganglioside activator
GPC4 glypican 4
HFE hemochromatosis
HLA-F major histocompatibility complex, class I, F
HTRA2 HtrA serine peptidase 2
IFIH1 interferon induced with helicase C domain 1
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL4R interleukin 4 receptor
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KCTD17 potassium channel tetramerization domain containing 17
KDM7A lysine (K)-specific demethylase 7A
KIF5C kinesin family member 5C
LMNB1 lamin B1
LYPD1 LY6/PLAUR domain containing 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAPT microtubule-associated protein tau
MBNL2 muscleblind-like splicing regulator 2
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MECOM MDS1 and EVI1 complex locus
MET MET proto-oncogene, receptor tyrosine kinase
MTSS1 metastasis suppressor 1
MUC3A mucin 3A, cell surface associated
NMT2 N-myristoyltransferase 2
PDGFB platelet-derived growth factor beta polypeptide
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLXNA1 plexin A1
PML promyelocytic leukemia
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PRDX2 peroxiredoxin 2
PRPH peripherin
PTCH1 patched 1
PTPRA protein tyrosine phosphatase, receptor type, A
PTRF polymerase I and transcript release factor
RAB11B RAB11B, member RAS oncogene family
RCAN1 regulator of calcineurin 1
REEP1 receptor accessory protein 1
RIPK2 receptor-interacting serine-threonine kinase 2
SAFB2 scaffold attachment factor B2
SEC63 SEC63 homolog (S. cerevisiae)
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SGSM3 small G protein signaling modulator 3
SMCO4 single-pass membrane protein with coiled-coil domains 4
SNTA1 syntrophin, alpha 1
SOX12 SRY (sex determining region Y)-box 12
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STON1 stonin 1
SYT17 synaptotagmin XVII
TBX5 T-box 5
TESC tescalcin
TIMELESS timeless circadian clock
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
UBE2I ubiquitin-conjugating enzyme E2I
ULBP2 UL16 binding protein 2
VGF VGF nerve growth factor inducible
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZCCHC24 zinc finger, CCHC domain containing 24
ZMYM6 zinc finger, MYM-type 6
ZNF165 zinc finger protein 165
ZNF573 zinc finger protein 573
ZNF589 zinc finger protein 589
ZNF821 zinc finger protein 821
ZSCAN12 zinc finger and SCAN domain containing 12

decreased expression

Symbol Name
AKR1C2 aldo-keto reductase family 1, member C2
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ANP32A-IT1 ANP32A intronic transcript 1
ARHGAP5 Rho GTPase activating protein 5
ATXN2 ataxin 2
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BCL2L2 BCL2-like 2
BCL7A B-cell CLL/lymphoma 7A
BCL9 B-cell CLL/lymphoma 9
C17ORF80 chromosome 17 open reading frame 80
C19ORF24 chromosome 19 open reading frame 24
C19ORF40 chromosome 19 open reading frame 40
C19ORF73 chromosome 19 open reading frame 73
C3ORF52 chromosome 3 open reading frame 52
CA5BP1 carbonic anhydrase VB pseudogene 1
CAMK1 calcium/calmodulin-dependent protein kinase I
CCDC9 coiled-coil domain containing 9
CCP110 centriolar coiled coil protein 110kDa
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CEP85 centrosomal protein 85kDa
CIC capicua transcriptional repressor
CLCN5 chloride channel, voltage-sensitive 5
CTAGE9 CTAGE family, member 9
CUL9 cullin 9
DCAF10 DDB1 and CUL4 associated factor 10
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DUSP13 dual specificity phosphatase 13
EFHD1 EF-hand domain family, member D1
EPPK1 epiplakin 1
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
GMIP GEM interacting protein
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPATCH3 G patch domain containing 3
GRHL2 grainyhead-like 2 (Drosophila)
HIST1H2AJ histone cluster 1, H2aj
HIST1H2AL histone cluster 1, H2al
HOXC10 homeobox C10
INPP5J inositol polyphosphate-5-phosphatase J
INSIG2 insulin induced gene 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
LOC257152 uncharacterized LOC257152
LOC390998 ribosomal protein L10 pseudogene
LRRC61 leucine rich repeat containing 61
LYPD3 LY6/PLAUR domain containing 3
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MBTD1 mbt domain containing 1
MEFV Mediterranean fever
MITF microphthalmia-associated transcription factor
MVD mevalonate (diphospho) decarboxylase
MYO1D myosin ID
NBEAL2 neurobeachin-like 2
NCALD neurocalcin delta
NPFFR1 neuropeptide FF receptor 1
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
PHACTR4 phosphatase and actin regulator 4
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLD2 phospholipase D2
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RABL3 RAB, member of RAS oncogene family-like 3
RASA2 RAS p21 protein activator 2
RBM42 RNA binding motif protein 42
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1
SCML2 sex comb on midleg-like 2 (Drosophila)
SDCCAG3 serologically defined colon cancer antigen 3
SH2D4A SH2 domain containing 4A
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SNAI2 snail family zinc finger 2
STBD1 starch binding domain 1
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THBS3 thrombospondin 3
THRAP3 thyroid hormone receptor associated protein 3
TMEM184C transmembrane protein 184C
TMEM39B transmembrane protein 39B
TPRA1 transmembrane protein, adipocyte asscociated 1
TRAIP TRAF interacting protein
TRIM25 tripartite motif containing 25
TRPM4 transient receptor potential cation channel, subfamily M, member 4
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
URGCP upregulator of cell proliferation
VWA1 von Willebrand factor A domain containing 1
VWA9 von Willebrand factor A domain containing 9
WDR91 WD repeat domain 91
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF141 zinc finger protein 141
ZNF205 zinc finger protein 205
ZNF324 zinc finger protein 324
ZNF408 zinc finger protein 408
ZNF696 zinc finger protein 696
ZNF747 zinc finger protein 747
ZSCAN26 zinc finger and SCAN domain containing 26