valproic acid-1634 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the valproic acid-1634 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AHNAK2 AHNAK nucleoprotein 2
ANKMY1 ankyrin repeat and MYND domain containing 1
ARMCX1 armadillo repeat containing, X-linked 1
ARMCX2 armadillo repeat containing, X-linked 2
BBX bobby sox homolog (Drosophila)
BLVRA biliverdin reductase A
BTN2A2 butyrophilin, subfamily 2, member A2
C2ORF27A chromosome 2 open reading frame 27A
C3 complement component 3
CASZ1 castor zinc finger 1
CEMIP cell migration inducing protein, hyaluronan binding
CEP104 centrosomal protein 104kDa
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CNPPD1 cyclin Pas1/PHO80 domain containing 1
CYR61 cysteine-rich, angiogenic inducer, 61
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
EFNB3 ephrin-B3
EGR1 early growth response 1
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
ETV5 ets variant 5
EVA1B eva-1 homolog B (C. elegans)
FYN FYN proto-oncogene, Src family tyrosine kinase
GLRX glutaredoxin (thioltransferase)
GPC4 glypican 4
GPM6B glycoprotein M6B
GPRC5B G protein-coupled receptor, class C, group 5, member B
GYG2 glycogenin 2
HLA-A major histocompatibility complex, class I, A
HPS1 Hermansky-Pudlak syndrome 1
IL11 interleukin 11
JAG1 jagged 1
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KIF5C kinesin family member 5C
KLHL23 kelch-like family member 23
LIN7A lin-7 homolog A (C. elegans)
LMAN1 lectin, mannose-binding, 1
LYN LYN proto-oncogene, Src family tyrosine kinase
LYPD1 LY6/PLAUR domain containing 1
MAP1B microtubule-associated protein 1B
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MECOM MDS1 and EVI1 complex locus
METTL7A methyltransferase like 7A
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MID1 midline 1
MMD monocyte to macrophage differentiation-associated
MTSS1 metastasis suppressor 1
MXI1 MAX interactor 1, dimerization protein
NDRG2 NDRG family member 2
NPTX1 neuronal pentraxin I
PAPPA2 pappalysin 2
PGBD5 piggyBac transposable element derived 5
PGM1 phosphoglucomutase 1
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLIN2 perilipin 2
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PPT2 palmitoyl-protein thioesterase 2
PROS1 protein S (alpha)
PTCH1 patched 1
PTRF polymerase I and transcript release factor
RAB29 RAB29, member RAS oncogene family
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
REEP1 receptor accessory protein 1
REEP2 receptor accessory protein 2
RGS19 regulator of G-protein signaling 19
RNF2 ring finger protein 2
RPL13P5 ribosomal protein L13 pseudogene 5
SDC2 syndecan 2
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SFXN3 sideroflexin 3
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SORBS3 sorbin and SH3 domain containing 3
SOX4 SRY (sex determining region Y)-box 4
SP1 Sp1 transcription factor
SRPX sushi-repeat containing protein, X-linked
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STX1A syntaxin 1A (brain)
STXBP1 syntaxin binding protein 1
TESC tescalcin
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TOX4 TOX high mobility group box family member 4
TRIP11 thyroid hormone receptor interactor 11
TTC33 tetratricopeptide repeat domain 33
TTC9 tetratricopeptide repeat domain 9
TUBA4A tubulin, alpha 4a
TUBGCP4 tubulin, gamma complex associated protein 4
ULBP2 UL16 binding protein 2
UTRN utrophin
VGF VGF nerve growth factor inducible
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZCCHC24 zinc finger, CCHC domain containing 24
ZER1 zyg-11 related, cell cycle regulator
ZNF204P zinc finger protein 204, pseudogene
ZNF227 zinc finger protein 227
ZNF442 zinc finger protein 442
ZNF606 zinc finger protein 606

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ACVR2B activin A receptor, type IIB
ACYP2 acylphosphatase 2, muscle type
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALPK1 alpha-kinase 1
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARMC6 armadillo repeat containing 6
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
C19ORF40 chromosome 19 open reading frame 40
C5ORF45 chromosome 5 open reading frame 45
C7ORF43 chromosome 7 open reading frame 43
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CAMTA2 calmodulin binding transcription activator 2
CCDC186 coiled-coil domain containing 186
CCDC94 coiled-coil domain containing 94
CCP110 centriolar coiled coil protein 110kDa
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD320 CD320 molecule
CLDN15 claudin 15
CSTA cystatin A (stefin A)
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DHDDS dehydrodolichyl diphosphate synthase
DHRS3 dehydrogenase/reductase (SDR family) member 3
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DUSP8 dual specificity phosphatase 8
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFNA1 ephrin-A1
ERN2 endoplasmic reticulum to nucleus signaling 2
FNTB farnesyltransferase, CAAX box, beta
GID4 GID complex subunit 4
GINS4 GINS complex subunit 4 (Sld5 homolog)
GTF2I general transcription factor IIi
GUSBP3 glucuronidase, beta pseudogene 3
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
IRF6 interferon regulatory factor 6
KANSL2 KAT8 regulatory NSL complex subunit 2
KAT2A K(lysine) acetyltransferase 2A
KDM5C lysine (K)-specific demethylase 5C
KEAP1 kelch-like ECH-associated protein 1
KIAA0556 KIAA0556
LINC00115 long intergenic non-protein coding RNA 115
LMNB1 lamin B1
MCM9 minichromosome maintenance complex component 9
MPDU1 mannose-P-dolichol utilization defect 1
MRPL17 mitochondrial ribosomal protein L17
MSL2 male-specific lethal 2 homolog (Drosophila)
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MXD3 MAX dimerization protein 3
NSD1 nuclear receptor binding SET domain protein 1
OFD1 oral-facial-digital syndrome 1
PAN2 PAN2 poly(A) specific ribonuclease subunit
PARG poly (ADP-ribose) glycohydrolase
PARP16 poly (ADP-ribose) polymerase family, member 16
PBLD phenazine biosynthesis-like protein domain containing
PCNT pericentrin
PEPD peptidase D
PHACTR4 phosphatase and actin regulator 4
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RIBC2 RIB43A domain with coiled-coils 2
RIPK4 receptor-interacting serine-threonine kinase 4
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SH2D4A SH2 domain containing 4A
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMA4 glucuronidase, beta pseudogene
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
TBC1D17 TBC1 domain family, member 17
TBX19 T-box 19
TGFBI transforming growth factor, beta-induced, 68kDa
THBS3 thrombospondin 3
TLN1 talin 1
TMEM177 transmembrane protein 177
TMEM2 transmembrane protein 2
TMEM39B transmembrane protein 39B
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRAPPC2 trafficking protein particle complex 2
UBIAD1 UbiA prenyltransferase domain containing 1
UBQLN4 ubiquilin 4
UBXN8 UBX domain protein 8
USP18 ubiquitin specific peptidase 18
USP21 ubiquitin specific peptidase 21
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WDR76 WD repeat domain 76
ZBTB38 zinc finger and BTB domain containing 38
ZMAT3 zinc finger, matrin-type 3
ZNF205 zinc finger protein 205
ZNF250 zinc finger protein 250
ZNF324 zinc finger protein 324
ZNF33B zinc finger protein 33B
ZNF574 zinc finger protein 574