valproic acid-1078 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the valproic acid-1078 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4
ABHD3 abhydrolase domain containing 3
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
ARMCX1 armadillo repeat containing, X-linked 1
ATG13 autophagy related 13
BBX bobby sox homolog (Drosophila)
BEX4 brain expressed, X-linked 4
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CADPS2 Ca++-dependent secretion activator 2
CASP7 caspase 7, apoptosis-related cysteine peptidase
CCPG1 cell cycle progression 1
CD47 CD47 molecule
CEP170 centrosomal protein 170kDa
CEP76 centrosomal protein 76kDa
CPD carboxypeptidase D
CRY1 cryptochrome circadian clock 1
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2
CXORF56 chromosome X open reading frame 56
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DBN1 drebrin 1
EFNA3 ephrin-A3
EFNB3 ephrin-B3
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
ELOVL4 ELOVL fatty acid elongase 4
ELOVL6 ELOVL fatty acid elongase 6
ERO1L ERO1-like (S. cerevisiae)
FAM114A1 family with sequence similarity 114, member A1
FAM155B family with sequence similarity 155, member B
FCHSD2 FCH and double SH3 domains 2
FHL1 four and a half LIM domains 1
FKBP1A FK506 binding protein 1A, 12kDa
FOXN3 forkhead box N3
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
FZD1 frizzled class receptor 1
GTPBP3 GTP binding protein 3 (mitochondrial)
HECA headcase homolog (Drosophila)
IFT22 intraflagellar transport 22
ITGA6 integrin, alpha 6
ITM2B integral membrane protein 2B
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KDM7A lysine (K)-specific demethylase 7A
KIAA0895 KIAA0895
KIF5C kinesin family member 5C
MAGEH1 melanoma antigen family H1
MANEA mannosidase, endo-alpha
MANSC1 MANSC domain containing 1
MAP2K5 mitogen-activated protein kinase kinase 5
MAP4 microtubule-associated protein 4
MAP7D1 MAP7 domain containing 1
MAPT microtubule-associated protein tau
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MTCL1 microtubule crosslinking factor 1
MTSS1 metastasis suppressor 1
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
ORAI3 ORAI calcium release-activated calcium modulator 3
PAM peptidylglycine alpha-amidating monooxygenase
PARD6A par-6 family cell polarity regulator alpha
PDS5B PDS5 cohesin associated factor B
PGM1 phosphoglucomutase 1
PHKB phosphorylase kinase, beta
PINK1 PTEN induced putative kinase 1
PLCH1 phospholipase C, eta 1
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PVR poliovirus receptor
RAB29 RAB29, member RAS oncogene family
RANBP1 RAN binding protein 1
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RLN2 relaxin 2
RPL13P5 ribosomal protein L13 pseudogene 5
SALL2 spalt-like transcription factor 2
SFXN3 sideroflexin 3
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SMAD6 SMAD family member 6
SMCO4 single-pass membrane protein with coiled-coil domains 4
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNX16 sorting nexin 16
SOAT1 sterol O-acyltransferase 1
SOCS5 suppressor of cytokine signaling 5
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STX2 syntaxin 2
STXBP1 syntaxin binding protein 1
SUGP1 SURP and G patch domain containing 1
SYT17 synaptotagmin XVII
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TMF1 TATA element modulatory factor 1
TRAF4 TNF receptor-associated factor 4
TRIM2 tripartite motif containing 2
TTC9 tetratricopeptide repeat domain 9
WASF1 WAS protein family, member 1
XYLT2 xylosyltransferase II
ZBTB43 zinc finger and BTB domain containing 43

decreased expression

Symbol Name
AARSD1 alanyl-tRNA synthetase domain containing 1
ABHD17B abhydrolase domain containing 17B
ACYP2 acylphosphatase 2, muscle type
AHR aryl hydrocarbon receptor
AKR1C3 aldo-keto reductase family 1, member C3
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ASCC2 activating signal cointegrator 1 complex subunit 2
BOLA1 bolA family member 1
C10ORF2 chromosome 10 open reading frame 2
C1ORF35 chromosome 1 open reading frame 35
C9ORF91 chromosome 9 open reading frame 91
CDT1 chromatin licensing and DNA replication factor 1
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CEP85 centrosomal protein 85kDa
CINP cyclin-dependent kinase 2 interacting protein
CPSF3L cleavage and polyadenylation specific factor 3-like
CRELD2 cysteine-rich with EGF-like domains 2
DCAF10 DDB1 and CUL4 associated factor 10
DDIT3 DNA-damage-inducible transcript 3
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DESI1 desumoylating isopeptidase 1
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
E4F1 E4F transcription factor 1
ECSIT ECSIT signalling integrator
EDC3 enhancer of mRNA decapping 3
EFNA1 ephrin-A1
EPS8L2 EPS8-like 2
EXOSC10 exosome component 10
EXOSC9 exosome component 9
FAN1 FANCD2/FANCI-associated nuclease 1
FIP1L1 factor interacting with PAPOLA and CPSF1
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GNA13 guanine nucleotide binding protein (G protein), alpha 13
HOOK1 hook microtubule-tethering protein 1
HP1BP3 heterochromatin protein 1, binding protein 3
IMMT inner membrane protein, mitochondrial
ING3 inhibitor of growth family, member 3
IRAK4 interleukin-1 receptor-associated kinase 4
IRF9 interferon regulatory factor 9
KAT2A K(lysine) acetyltransferase 2A
KATNBL1 katanin p80 subunit B-like 1
KIAA0020 KIAA0020
KLHL36 kelch-like family member 36
KRT8P12 keratin 8 pseudogene 12
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LOC100272216 uncharacterized LOC100272216
MAN2B2 mannosidase, alpha, class 2B, member 2
MED22 mediator complex subunit 22
METTL16 methyltransferase like 16
MPDU1 mannose-P-dolichol utilization defect 1
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma
NDC1 NDC1 transmembrane nucleoporin
NME6 NME/NM23 nucleoside diphosphate kinase 6
NOP2 NOP2 nucleolar protein
NR1D2 nuclear receptor subfamily 1, group D, member 2
ODF2 outer dense fiber of sperm tails 2
PHC2 polyhomeotic homolog 2 (Drosophila)
PMPCA peptidase (mitochondrial processing) alpha
POLR1E polymerase (RNA) I polypeptide E, 53kDa
PPCS phosphopantothenoylcysteine synthetase
PQLC1 PQ loop repeat containing 1
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPS17P5 ribosomal protein S17 pseudogene 5
RPS21 ribosomal protein S21
SECISBP2 SECIS binding protein 2
SETMAR SET domain and mariner transposase fusion gene
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMG9 SMG9 nonsense mediated mRNA decay factor
SPAG7 sperm associated antigen 7
SURF2 surfeit 2
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TBP TATA box binding protein
TGFB3 transforming growth factor, beta 3
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
THOC1 THO complex 1
TMEM39B transmembrane protein 39B
TMEM57 transmembrane protein 57
TOE1 target of EGR1, member 1 (nuclear)
TPRA1 transmembrane protein, adipocyte asscociated 1
TSC1 tuberous sclerosis 1
TWSG1 twisted gastrulation BMP signaling modulator 1
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae)
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae)
WRN Werner syndrome, RecQ helicase-like
ZBED8 zinc finger, BED-type containing 8
ZFHX3 zinc finger homeobox 3
ZNF124 zinc finger protein 124
ZNF248 zinc finger protein 248
ZNF254 zinc finger protein 254
ZNF33B zinc finger protein 33B
ZNF692 zinc finger protein 692
ZNF778 zinc finger protein 778
ZNF787 zinc finger protein 787