valproic acid-1060 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the valproic acid-1060 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACVR2B activin A receptor, type IIB
ADD3 adducin 3 (gamma)
ADGRL1 adhesion G protein-coupled receptor L1
AHDC1 AT hook, DNA binding motif, containing 1
ALPK1 alpha-kinase 1
ATM ATM serine/threonine kinase
CASKIN2 CASK interacting protein 2
CASP6 caspase 6, apoptosis-related cysteine peptidase
CCNK cyclin K
CDK1 cyclin-dependent kinase 1
CDK16 cyclin-dependent kinase 16
CHST10 carbohydrate sulfotransferase 10
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
DCAF11 DDB1 and CUL4 associated factor 11
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DUSP4 dual specificity phosphatase 4
EFNA3 ephrin-A3
EIF1 eukaryotic translation initiation factor 1
ELF4 E74-like factor 4 (ets domain transcription factor)
ESRP2 epithelial splicing regulatory protein 2
FADS1 fatty acid desaturase 1
FHL1 four and a half LIM domains 1
FOXD1 forkhead box D1
FXR2 fragile X mental retardation, autosomal homolog 2
FZD7 frizzled class receptor 7
GADD45A growth arrest and DNA-damage-inducible, alpha
GFER growth factor, augmenter of liver regeneration
HABP4 hyaluronan binding protein 4
HIST1H4C histone cluster 1, H4c
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
IFNAR2 interferon (alpha, beta and omega) receptor 2
ING1 inhibitor of growth family, member 1
JADE2 jade family PHD finger 2
KAT2A K(lysine) acetyltransferase 2A
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KDM6A lysine (K)-specific demethylase 6A
LOC100287590 uncharacterized LOC100287590
LRBA LPS-responsive vesicle trafficking, beach and anchor containing
MAP4 microtubule-associated protein 4
METTL5 methyltransferase like 5
NDRG4 NDRG family member 4
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NOTCH1 notch 1
NR2C1 nuclear receptor subfamily 2, group C, member 1
NUP98 nucleoporin 98kDa
PEX11A peroxisomal biogenesis factor 11 alpha
PHF3 PHD finger protein 3
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLCG1 phospholipase C, gamma 1
POFUT2 protein O-fucosyltransferase 2
POLR2J4 polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRRC2A proline-rich coiled-coil 2A
PTTG3P pituitary tumor-transforming 3, pseudogene
PVR poliovirus receptor
RAB8B RAB8B, member RAS oncogene family
RBM48 RNA binding motif protein 48
RND2 Rho family GTPase 2
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RUFY2 RUN and FYVE domain containing 2
SEC63 SEC63 homolog (S. cerevisiae)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SF3A3 splicing factor 3a, subunit 3, 60kDa
SGSM2 small G protein signaling modulator 2
SIKE1 suppressor of IKBKE 1
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOX4 SRY (sex determining region Y)-box 4
SPATA2L spermatogenesis associated 2-like
STAT5B signal transducer and activator of transcription 5B
STK16 serine/threonine kinase 16
STK4 serine/threonine kinase 4
SUGP1 SURP and G patch domain containing 1
SUN2 Sad1 and UNC84 domain containing 2
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
TBC1D4 TBC1 domain family, member 4
TDRD3 tudor domain containing 3
TELO2 telomere maintenance 2
TGFB1 transforming growth factor, beta 1
THADA thyroid adenoma associated
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TLE3 transducin-like enhancer of split 3
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast)
TRAK1 trafficking protein, kinesin binding 1
TSKU tsukushi, small leucine rich proteoglycan
UBQLN4 ubiquilin 4
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
VWA1 von Willebrand factor A domain containing 1
VWA8 von Willebrand factor A domain containing 8
WDR48 WD repeat domain 48
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
ZMYND8 zinc finger, MYND-type containing 8
ZNF14 zinc finger protein 14
ZNF302 zinc finger protein 302
ZNF557 zinc finger protein 557

decreased expression

Symbol Name
ACSS3 acyl-CoA synthetase short-chain family member 3
ACYP2 acylphosphatase 2, muscle type
APH1B APH1B gamma secretase subunit
APIP APAF1 interacting protein
ARHGAP12 Rho GTPase activating protein 12
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ASPHD1 aspartate beta-hydroxylase domain containing 1
AXIN1 axin 1
BAGE B melanoma antigen
BRD9 bromodomain containing 9
BRIX1 BRX1, biogenesis of ribosomes
C14ORF132 chromosome 14 open reading frame 132
C9ORF114 chromosome 9 open reading frame 114
CCNJ cyclin J
CCNT1 cyclin T1
CDKN2AIP CDKN2A interacting protein
CHKB choline kinase beta
CLASRP CLK4-associating serine/arginine rich protein
CLK1 CDC-like kinase 1
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
COQ3 coenzyme Q3 methyltransferase
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2
DDIT3 DNA-damage-inducible transcript 3
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DGKD diacylglycerol kinase, delta 130kDa
DOLPP1 dolichyldiphosphatase 1
ECH1 enoyl CoA hydratase 1, peroxisomal
ECHDC1 ethylmalonyl-CoA decarboxylase 1
FBXO46 F-box protein 46
FSD1 fibronectin type III and SPRY domain containing 1
GATA6 GATA binding protein 6
GFOD1 glucose-fructose oxidoreductase domain containing 1
GHR growth hormone receptor
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GRAMD4 GRAM domain containing 4
GTF2I general transcription factor IIi
HIST1H2BI histone cluster 1, H2bi
HYAL2 hyaluronoglucosaminidase 2
ICE2 interactor of little elongation complex ELL subunit 2
IFT81 intraflagellar transport 81
IREB2 iron-responsive element binding protein 2
KATNBL1 katanin p80 subunit B-like 1
KLHL26 kelch-like family member 26
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MAP9 microtubule-associated protein 9
MOSPD3 motile sperm domain containing 3
MPI mannose phosphate isomerase
MSRA methionine sulfoxide reductase A
MT1HL1 metallothionein 1H-like 1
MTERF1 mitochondrial transcription termination factor 1
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
NCSTN nicastrin
NPM3 nucleophosmin/nucleoplasmin 3
NPY1R neuropeptide Y receptor Y1
NR1D2 nuclear receptor subfamily 1, group D, member 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
NRBF2 nuclear receptor binding factor 2
PARG poly (ADP-ribose) glycohydrolase
PCNXL4 pecanex-like 4 (Drosophila)
PFDN1 prefoldin subunit 1
PNRC1 proline-rich nuclear receptor coactivator 1
POR P450 (cytochrome) oxidoreductase
PPP1R3C protein phosphatase 1, regulatory subunit 3C
RAMP1 receptor (G protein-coupled) activity modifying protein 1
REEP4 receptor accessory protein 4
RNF25 ring finger protein 25
RNH1 ribonuclease/angiogenin inhibitor 1
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
RWDD3 RWD domain containing 3
SARS2 seryl-tRNA synthetase 2, mitochondrial
SAV1 salvador family WW domain containing protein 1
SLC22A18 solute carrier family 22, member 18
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC46A3 solute carrier family 46, member 3
SNIP1 Smad nuclear interacting protein 1
SNX16 sorting nexin 16
SP1 Sp1 transcription factor
STXBP3 syntaxin binding protein 3
SYNJ2BP synaptojanin 2 binding protein
THOC1 THO complex 1
TMEM177 transmembrane protein 177
TMEM184C transmembrane protein 184C
TMEM38B transmembrane protein 38B
TPTE transmembrane phosphatase with tensin homology
TRNAU1AP tRNA selenocysteine 1 associated protein 1
UBE2W ubiquitin-conjugating enzyme E2W (putative)
VWA9 von Willebrand factor A domain containing 9
ZFAND3 zinc finger, AN1-type domain 3
ZNF273 zinc finger protein 273
ZNF282 zinc finger protein 282
ZNF408 zinc finger protein 408
ZNF480 zinc finger protein 480
ZNF665 zinc finger protein 665
ZNF675 zinc finger protein 675