valproic acid-1020 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the valproic acid-1020 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ARMCX2 armadillo repeat containing, X-linked 2
ARSB arylsulfatase B
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASIC1 acid sensing (proton gated) ion channel 1
BTN2A2 butyrophilin, subfamily 2, member A2
CAPRIN2 caprin family member 2
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC28B coiled-coil domain containing 28B
CCPG1 cell cycle progression 1
CERK ceramide kinase
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLUAP1 clusterin associated protein 1
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DPYSL4 dihydropyrimidinase-like 4
DTX4 deltex 4, E3 ubiquitin ligase
EFNA3 ephrin-A3
EFNB3 ephrin-B3
EHD2 EH-domain containing 2
ELOVL2 ELOVL fatty acid elongase 2
ELOVL4 ELOVL fatty acid elongase 4
ENGASE endo-beta-N-acetylglucosaminidase
FAM184A family with sequence similarity 184, member A
FGD1 FYVE, RhoGEF and PH domain containing 1
FHL1 four and a half LIM domains 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GAS6 growth arrest-specific 6
GK3P glycerol kinase 3 pseudogene
GLRX glutaredoxin (thioltransferase)
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPC4 glypican 4
GPR153 G protein-coupled receptor 153
GPRC5B G protein-coupled receptor, class C, group 5, member B
GRK5 G protein-coupled receptor kinase 5
HLA-C major histocompatibility complex, class I, C
HMGN5 high mobility group nucleosome binding domain 5
HOXA1 homeobox A1
IFT27 intraflagellar transport 27
JAG1 jagged 1
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KIF5C kinesin family member 5C
KREMEN2 kringle containing transmembrane protein 2
LARP6 La ribonucleoprotein domain family, member 6
MAP1B microtubule-associated protein 1B
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAP3K8 mitogen-activated protein kinase kinase kinase 8
METTL7A methyltransferase like 7A
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MRPL41 mitochondrial ribosomal protein L41
MTSS1 metastasis suppressor 1
NDRG2 NDRG family member 2
NIPAL2 NIPA-like domain containing 2
NKX3-2 NK3 homeobox 2
NRSN2 neurensin 2
PDE9A phosphodiesterase 9A
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLAU plasminogen activator, urokinase
PLK3 polo-like kinase 3
PRPH peripherin
PRSS16 protease, serine, 16 (thymus)
PTBP3 polypyrimidine tract binding protein 3
PTCH1 patched 1
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RALGDS ral guanine nucleotide dissociation stimulator
REEP1 receptor accessory protein 1
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RTN2 reticulon 2
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SFXN3 sideroflexin 3
SGSM2 small G protein signaling modulator 2
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SMCO4 single-pass membrane protein with coiled-coil domains 4
SOAT1 sterol O-acyltransferase 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STXBP1 syntaxin binding protein 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TESC tescalcin
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TTC28 tetratricopeptide repeat domain 28
TTC33 tetratricopeptide repeat domain 33
TTC9 tetratricopeptide repeat domain 9
ULBP2 UL16 binding protein 2
UPP1 uridine phosphorylase 1
USB1 U6 snRNA biogenesis 1
WDR19 WD repeat domain 19
ZER1 zyg-11 related, cell cycle regulator
ZNF10 zinc finger protein 10
ZNF204P zinc finger protein 204, pseudogene
ZNF286A zinc finger protein 286A
ZNF34 zinc finger protein 34
ZNF365 zinc finger protein 365
ZNF821 zinc finger protein 821
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ABHD17B abhydrolase domain containing 17B
ANP32A-IT1 ANP32A intronic transcript 1
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARMC6 armadillo repeat containing 6
BCAS1 breast carcinoma amplified sequence 1
BRIX1 BRX1, biogenesis of ribosomes
C11ORF30 chromosome 11 open reading frame 30
C19ORF40 chromosome 19 open reading frame 40
CAPG capping protein (actin filament), gelsolin-like
CCDC130 coiled-coil domain containing 130
CCNK cyclin K
CDKL3 cyclin-dependent kinase-like 3
CLIP4 CAP-GLY domain containing linker protein family, member 4
CTAGE9 CTAGE family, member 9
DEAF1 DEAF1 transcription factor
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DNAL4 dynein, axonemal, light chain 4
EPS8L2 EPS8-like 2
ESRP2 epithelial splicing regulatory protein 2
FANCC Fanconi anemia, complementation group C
FOSL1 FOS-like antigen 1
GDAP1 ganglioside induced differentiation associated protein 1
GMEB1 glucocorticoid modulatory element binding protein 1
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPR87 G protein-coupled receptor 87
GRTP1 growth hormone regulated TBC protein 1
GRWD1 glutamate-rich WD repeat containing 1
GTF2I general transcription factor IIi
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HOXC10 homeobox C10
HYAL2 hyaluronoglucosaminidase 2
IRF7 interferon regulatory factor 7
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KDM5C lysine (K)-specific demethylase 5C
KRT15 keratin 15, type I
LINS lines homolog (Drosophila)
LOC100287590 uncharacterized LOC100287590
LRRC37A3 leucine rich repeat containing 37, member A3
MALL mal, T-cell differentiation protein-like
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCM9 minichromosome maintenance complex component 9
MDM4 MDM4, p53 regulator
MFSD11 major facilitator superfamily domain containing 11
MON1B MON1 secretory trafficking family member B
MTA2 metastasis associated 1 family, member 2
MYLIP myosin regulatory light chain interacting protein
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NEK11 NIMA-related kinase 11
NPY5R neuropeptide Y receptor Y5
PCSK7 proprotein convertase subtilisin/kexin type 7
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PISD phosphatidylserine decarboxylase
PLD3 phospholipase D family, member 3
PODXL2 podocalyxin-like 2
POLH polymerase (DNA directed), eta
PPCDC phosphopantothenoylcysteine decarboxylase
PPP1R3C protein phosphatase 1, regulatory subunit 3C
RBM14 RNA binding motif protein 14
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RPAP2 RNA polymerase II associated protein 2
SAYSD1 SAYSVFN motif domain containing 1
SCAMP4 secretory carrier membrane protein 4
SCD5 stearoyl-CoA desaturase 5
SECISBP2 SECIS binding protein 2
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SNAI2 snail family zinc finger 2
SNX15 sorting nexin 15
SPINK4 serine peptidase inhibitor, Kazal type 4
TCTN2 tectonic family member 2
TDRD1 tudor domain containing 1
TFF3 trefoil factor 3 (intestinal)
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TNIP1 TNFAIP3 interacting protein 1
TPTE transmembrane phosphatase with tensin homology
TRIP10 thyroid hormone receptor interactor 10
TUBG2 tubulin, gamma 2
UBQLN4 ubiquilin 4
UNKL unkempt family zinc finger-like
URM1 ubiquitin related modifier 1
USP20 ubiquitin specific peptidase 20
USP6NL USP6 N-terminal like
VEGFC vascular endothelial growth factor C
WDR18 WD repeat domain 18
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
XYLT2 xylosyltransferase II
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBTB3 zinc finger and BTB domain containing 3
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF226 zinc finger protein 226
ZNF280D zinc finger protein 280D
ZNF510 zinc finger protein 510
ZNF770 zinc finger protein 770