valproic acid-1002 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the valproic acid-1002 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ANKRD6 ankyrin repeat domain 6
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ATF7IP activating transcription factor 7 interacting protein
ATN1 atrophin 1
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BICD1 bicaudal D homolog 1 (Drosophila)
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CCDC132 coiled-coil domain containing 132
CCPG1 cell cycle progression 1
CDH8 cadherin 8, type 2
CDK13 cyclin-dependent kinase 13
CEP290 centrosomal protein 290kDa
CHMP6 charged multivesicular body protein 6
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
DBF4B DBF4 zinc finger B
EFNB3 ephrin-B3
EGR1 early growth response 1
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ERO1L ERO1-like (S. cerevisiae)
F2R coagulation factor II (thrombin) receptor
FADS3 fatty acid desaturase 3
FBXO38 F-box protein 38
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GSK3A glycogen synthase kinase 3 alpha
GUSBP3 glucuronidase, beta pseudogene 3
H2AFX H2A histone family, member X
HBS1L HBS1-like translational GTPase
HIPK2 homeodomain interacting protein kinase 2
HIPK3 homeodomain interacting protein kinase 3
HSF2 heat shock transcription factor 2
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
JAG1 jagged 1
KCNK15 potassium channel, two pore domain subfamily K, member 15
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KDM4C lysine (K)-specific demethylase 4C
LAMC2 laminin, gamma 2
LOC390998 ribosomal protein L10 pseudogene
LPP LIM domain containing preferred translocation partner in lipoma
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAPK13 mitogen-activated protein kinase 13
METTL5 methyltransferase like 5
METTL7A methyltransferase like 7A
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MTAP methylthioadenosine phosphorylase
MTRF1L mitochondrial translational release factor 1-like
NDRG2 NDRG family member 2
NEB nebulin
NFRKB nuclear factor related to kappaB binding protein
NIPAL2 NIPA-like domain containing 2
NR2F1 nuclear receptor subfamily 2, group F, member 1
NRF1 nuclear respiratory factor 1
PADI1 peptidyl arginine deiminase, type I
PCNX pecanex homolog (Drosophila)
PDE4DIP phosphodiesterase 4D interacting protein
PHTF2 putative homeodomain transcription factor 2
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PKNOX1 PBX/knotted 1 homeobox 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLK4 polo-like kinase 4
POFUT1 protein O-fucosyltransferase 1
PPAP2B phosphatidic acid phosphatase type 2B
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PPP1R3D protein phosphatase 1, regulatory subunit 3D
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPRA protein tyrosine phosphatase, receptor type, A
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RABGAP1L RAB GTPase activating protein 1-like
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RPL10L ribosomal protein L10-like
RREB1 ras responsive element binding protein 1
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SCAND2P SCAN domain containing 2 pseudogene
SIPA1L3 signal-induced proliferation-associated 1 like 3
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SMIM14 small integral membrane protein 14
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa
SNX13 sorting nexin 13
SP1 Sp1 transcription factor
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SSBP1 single-stranded DNA binding protein 1, mitochondrial
STAT2 signal transducer and activator of transcription 2, 113kDa
STK4 serine/threonine kinase 4
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TMEM209 transmembrane protein 209
UPP1 uridine phosphorylase 1
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
WDR33 WD repeat domain 33
ZBTB33 zinc finger and BTB domain containing 33
ZFHX2 zinc finger homeobox 2
ZNF345 zinc finger protein 345
ZNF446 zinc finger protein 446
ZNF589 zinc finger protein 589
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
ACSL4 acyl-CoA synthetase long-chain family member 4
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADM adrenomedullin
ANKRD36 ankyrin repeat domain 36
APOD apolipoprotein D
ARID3B AT rich interactive domain 3B (BRIGHT-like)
C7ORF43 chromosome 7 open reading frame 43
CAMKMT calmodulin-lysine N-methyltransferase
CCNO cyclin O
CCNT1 cyclin T1
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHST10 carbohydrate sulfotransferase 10
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLIP4 CAP-GLY domain containing linker protein family, member 4
CRABP1 cellular retinoic acid binding protein 1
CTAGE9 CTAGE family, member 9
CTC1 CTS telomere maintenance complex component 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DCAF17 DDB1 and CUL4 associated factor 17
DDIT3 DNA-damage-inducible transcript 3
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DGKE diacylglycerol kinase, epsilon 64kDa
DIXDC1 DIX domain containing 1
EGLN3 egl-9 family hypoxia-inducible factor 3
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1
FAM160B2 family with sequence similarity 160, member B2
FOSL1 FOS-like antigen 1
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GFOD1 glucose-fructose oxidoreductase domain containing 1
GLI3 GLI family zinc finger 3
HCFC1 host cell factor C1
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIRA histone cell cycle regulator
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IRF7 interferon regulatory factor 7
KLHDC4 kelch domain containing 4
LRRC61 leucine rich repeat containing 61
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LYPLA2P1 lysophospholipase II pseudogene 1
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MANSC1 MANSC domain containing 1
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MTMR12 myotubularin related protein 12
ORAI3 ORAI calcium release-activated calcium modulator 3
OXTR oxytocin receptor
PANK4 pantothenate kinase 4
PAQR6 progestin and adipoQ receptor family member VI
PARD6A par-6 family cell polarity regulator alpha
PCOLCE2 procollagen C-endopeptidase enhancer 2
PEX26 peroxisomal biogenesis factor 26
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
POLH polymerase (DNA directed), eta
PTK6 protein tyrosine kinase 6
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RFTN1 raftlin, lipid raft linker 1
RNF123 ring finger protein 123
RPAP2 RNA polymerase II associated protein 2
S100A4 S100 calcium binding protein A4
SCD5 stearoyl-CoA desaturase 5
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SETD1A SET domain containing 1A
SIN3B SIN3 transcription regulator family member B
SLC35F5 solute carrier family 35, member F5
SLC46A3 solute carrier family 46, member 3
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
STX5 syntaxin 5
SYT17 synaptotagmin XVII
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TCTN2 tectonic family member 2
TMEM104 transmembrane protein 104
TMEM2 transmembrane protein 2
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNS2 tensin 2
TPST2 tyrosylprotein sulfotransferase 2
TRIM5 tripartite motif containing 5
TTC4 tetratricopeptide repeat domain 4
TUBA4A tubulin, alpha 4a
UBQLN4 ubiquilin 4
UBXN6 UBX domain protein 6
URM1 ubiquitin related modifier 1
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZBED1 zinc finger, BED-type containing 1
ZBTB22 zinc finger and BTB domain containing 22
ZBTB48 zinc finger and BTB domain containing 48
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF14 zinc finger protein 14
ZNF212 zinc finger protein 212
ZNF282 zinc finger protein 282
ZNF587 zinc finger protein 587
ZNF611 zinc finger protein 611
ZNF668 zinc finger protein 668
ZNF721 zinc finger protein 721
ZNF816 zinc finger protein 816
ZNRD1-AS1 ZNRD1 antisense RNA 1