vacuolar part Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description Any constituent part of a vacuole, a closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. (Gene Ontology, GO_0044437)
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Genes

300 proteins localized to the vacuolar part cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 0.663342
SPPL2A signal peptide peptidase like 2A 0.663342
AHNAK AHNAK nucleoprotein 0.663342
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 0.663342
GABARAP GABA(A) receptor-associated protein 0.663342
TLDC1 TBC/LysM-associated domain containing 1 0.663342
FLOT1 flotillin 1 0.663342
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) 0.663342
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) 0.663342
ATP13A2 ATPase type 13A2 0.663342
C18ORF8 chromosome 18 open reading frame 8 0.663342
SPPL2B signal peptide peptidase like 2B 0.663342
SPHK2 sphingosine kinase 2 0.663342
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 0.663342
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.663342
HLA-DRB3 major histocompatibility complex, class II, DR beta 3 0.663342
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 0.663342
ZFYVE26 zinc finger, FYVE domain containing 26 0.663342
NCSTN nicastrin 0.663342
CLCN5 chloride channel, voltage-sensitive 5 0.663342
CLCN6 chloride channel, voltage-sensitive 6 0.663342
CLCN7 chloride channel, voltage-sensitive 7 0.663342
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.663342
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.663342
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 0.663342
TMEM8A transmembrane protein 8A 0.663342
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha 0.663342
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 0.663342
ATP6V1C2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 0.663342
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.663342
PQLC2 PQ loop repeat containing 2 0.663342
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 0.663342
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 0.663342
HLA-DMA major histocompatibility complex, class II, DM alpha 0.663342
CYB561A3 cytochrome b561 family, member A3 0.663342
LAMP1 lysosomal-associated membrane protein 1 0.663342
SLC30A2 solute carrier family 30 (zinc transporter), member 2 0.663342
M6PR mannose-6-phosphate receptor (cation dependent) 0.663342
ANPEP alanyl (membrane) aminopeptidase 0.663342
RRAGA Ras-related GTP binding A 0.663342
CLN3 ceroid-lipofuscinosis, neuronal 3 0.663342
CLN5 ceroid-lipofuscinosis, neuronal 5 0.663342
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.663342
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.663342
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4 0.663342
RRAGB Ras-related GTP binding B 0.663342
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae) 0.663342
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) 0.663342
LAMP2 lysosomal-associated membrane protein 2 0.663342
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.663342
ATG9A autophagy related 9A 0.663342
CD1B CD1b molecule 0.663342
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3 0.663342
ENPEP glutamyl aminopeptidase (aminopeptidase A) 0.663342
AP3D1 adaptor-related protein complex 3, delta 1 subunit 0.663342
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 0.663342
IFITM3 interferon induced transmembrane protein 3 0.663342
NEU1 sialidase 1 (lysosomal sialidase) 0.663342
NEU4 sialidase 4 0.663342
LITAF lipopolysaccharide-induced TNF factor 0.663342
VAMP8 vesicle-associated membrane protein 8 0.663342
CD1E CD1e molecule 0.663342
CD1D CD1d molecule 0.663342
GAA glucosidase, alpha; acid 0.663342
RAB14 RAB14, member RAS oncogene family 0.663342
RPTOR regulatory associated protein of MTOR, complex 1 0.663342
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) 0.663342
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae) 0.663342
SCARB1 scavenger receptor class B, member 1 0.663342
SCARB2 scavenger receptor class B, member 2 0.663342
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase 0.663342
MARCH9 membrane-associated ring finger (C3HC4) 9 0.663342
TMEM175 transmembrane protein 175 0.663342
VAMP7 vesicle-associated membrane protein 7 0.663342
ATP11C ATPase, class VI, type 11C 0.663342
ATP11A ATPase, class VI, type 11A 0.663342
SPNS1 spinster homolog 1 (Drosophila) 0.663342
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 0.663342
CD68 CD68 molecule 0.663342
CD63 CD63 molecule 0.663342
MCOLN1 mucolipin 1 0.663342
STX7 syntaxin 7 0.663342
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.663342
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma 0.663342
RNF13 ring finger protein 13 0.663342
SLC44A2 solute carrier family 44 (choline transporter), member 2 0.663342
RAB2A RAB2A, member RAS oncogene family 0.663342
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 0.663342
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle 0.663342
MYO7A myosin VIIA 0.663342
WIPI1 WD repeat domain, phosphoinositide interacting 1 0.663342
TMEM63A transmembrane protein 63A 0.663342
GPLD1 glycosylphosphatidylinositol specific phospholipase D1 0.663342
SLC26A11 solute carrier family 26 (anion exchanger), member 11 0.663342
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis) 0.663342
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.663342
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F 0.663342
GBA glucosidase, beta, acid 0.663342
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.663342
LAMP3 lysosomal-associated membrane protein 3 0.663342
GDAP2 ganglioside induced differentiation associated protein 2 0.663342
ARL8A ADP-ribosylation factor-like 8A 0.663342
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 0.663342
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 0.663342
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 0.663342
TPCN2 two pore segment channel 2 0.663342
VPS33B vacuolar protein sorting 33 homolog B (yeast) 0.663342
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae) 0.663342
MFSD8 major facilitator superfamily domain containing 8 0.663342
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.663342
STARD3NL STARD3 N-terminal like 0.663342
ARL8B ADP-ribosylation factor-like 8B 0.663342
FASLG Fas ligand (TNF superfamily, member 6) 0.663342
CP ceruloplasmin (ferroxidase) 0.663342
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.663342
AP3B1 adaptor-related protein complex 3, beta 1 subunit 0.663342
HLA-DOB major histocompatibility complex, class II, DO beta 0.663342
HLA-DOA major histocompatibility complex, class II, DO alpha 0.663342
LRP2 low density lipoprotein receptor-related protein 2 0.663342
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 0.663342
TPCN1 two pore segment channel 1 0.663342
PLD1 phospholipase D1, phosphatidylcholine-specific 0.663342
STARD3 StAR-related lipid transfer (START) domain containing 3 0.663342
OCA2 oculocutaneous albinism II 0.663342
TMEM192 transmembrane protein 192 0.663342
GPR143 G protein-coupled receptor 143 0.663342
ANKFY1 ankyrin repeat and FYVE domain containing 1 0.663342
HPSE heparanase 0.663342
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 0.663342
TMEM165 transmembrane protein 165 0.663342
NPC1 Niemann-Pick disease, type C1 0.663342
LNPEP leucyl/cystinyl aminopeptidase 0.663342
HLA-DQB3 major histocompatibility complex, class II, DQ beta 3 0.663342
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 0.663342
SIDT2 SID1 transmembrane family, member 2 0.663342
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae) 0.663342
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase 0.663342
MIOS missing oocyte, meiosis regulator, homolog (Drosophila) 0.663342
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1 0.663342
VASN vasorin 0.663342
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 0.663342
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8 0.663342
STX17 syntaxin 17 0.663342
DPP4 dipeptidyl-peptidase 4 0.663342
WDR11 WD repeat domain 11 0.663342
TMEM106B transmembrane protein 106B 0.663342
SLC35F6 solute carrier family 35, member F6 0.663342
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1 0.663342
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 0.663342
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.663342
STK11IP serine/threonine kinase 11 interacting protein 0.663342
ECE1 endothelin converting enzyme 1 0.663342
SPG11 spastic paraplegia 11 (autosomal recessive) 0.663342
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 0.663342
RILP Rab interacting lysosomal protein 0.663342
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4 0.663342
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.663342
EGF epidermal growth factor 0.663342
CTNS cystinosin, lysosomal cystine transporter 0.663342
TLR3 toll-like receptor 3 0.663342
ACP2 acid phosphatase 2, lysosomal 0.663342
ACPP acid phosphatase, prostate 0.663342
HLA-DRA major histocompatibility complex, class II, DR alpha 0.663342
DEPDC5 DEP domain containing 5 0.663342
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.663342
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 0.663342
NSF N-ethylmaleimide-sensitive factor 0.663342
TMEM59 transmembrane protein 59 0.663342
PI4K2A phosphatidylinositol 4-kinase type 2 alpha 0.663342
DAPK2 death-associated protein kinase 2 0.663342
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 0.663342
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 0.663342
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4 0.663342
VTI1B vesicle transport through interaction with t-SNAREs 1B 0.663342
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 0.663342
RNASET2 ribonuclease T2 0.663342
TMBIM1 transmembrane BAX inhibitor motif containing 1 0.663342
TECPR1 tectonin beta-propeller repeat containing 1 0.663342
RAB5C RAB5C, member RAS oncogene family 0.663342
COL6A1 collagen, type VI, alpha 1 0.663342
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 0.663342
GABARAPL2 GABA(A) receptor-associated protein-like 2 0.663342
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 0.663342
WDR41 WD repeat domain 41 0.663342
AP3M1 adaptor-related protein complex 3, mu 1 subunit 0.663342
MFSD12 major facilitator superfamily domain containing 12 0.663342
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13 0.663342
VCAN versican 0.237908
IDS iduronate 2-sulfatase 0.237908
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum) 0.237908
PRELP proline/arginine-rich end leucine-rich repeat protein 0.237908
GUSB glucuronidase, beta 0.237908
GLA galactosidase, alpha 0.237908
AP2M1 adaptor-related protein complex 2, mu 1 subunit 0.237908
BGN biglycan 0.237908
AP1B1 adaptor-related protein complex 1, beta 1 subunit 0.237908
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 0.237908
TLR9 toll-like receptor 9 0.237908
GC group-specific component (vitamin D binding protein) 0.237908
MYO6 myosin VI 0.237908
NCAN neurocan 0.237908
TLR8 toll-like receptor 8 0.237908
ACR acrosin 0.237908
FMOD fibromodulin 0.237908
OSBPL1A oxysterol binding protein-like 1A 0.237908
BCAN brevican 0.237908
TLR7 toll-like receptor 7 0.237908
GM2A GM2 ganglioside activator 0.237908
AP1S3 adaptor-related protein complex 1, sigma 3 subunit 0.237908
HSPG2 heparan sulfate proteoglycan 2 0.237908
GALNS galactosamine (N-acetyl)-6-sulfatase 0.237908
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 0.237908
DEFA1 defensin, alpha 1 0.237908
DEFA3 defensin, alpha 3, neutrophil-specific 0.237908
GNS glucosamine (N-acetyl)-6-sulfatase 0.237908
CTSV cathepsin V 0.237908
CTSS cathepsin S 0.237908
PSAP prosaposin 0.237908
KERA keratocan 0.237908
GLB1 galactosidase, beta 1 0.237908
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 0.237908
TRIM23 tripartite motif containing 23 0.237908
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 0.237908
AGRN agrin 0.237908
GIF gastric intrinsic factor (vitamin B synthesis) 0.237908
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C) 0.237908
CSPG4 chondroitin sulfate proteoglycan 4 0.237908
OMD osteomodulin 0.237908
CTSF cathepsin F 0.237908
CTSD cathepsin D 0.237908
CTSA cathepsin A 0.237908
GPC3 glypican 3 0.237908
GPC2 glypican 2 0.237908
GPC1 glypican 1 0.237908
LGMN legumain 0.237908
DAGLB diacylglycerol lipase, beta 0.237908
HLA-DMB major histocompatibility complex, class II, DM beta 0.237908
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 0.237908
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 0.237908
GPC4 glypican 4 0.237908
GPC5 glypican 5 0.237908
GPC6 glypican 6 0.237908
CTSL cathepsin L 0.237908
CTSK cathepsin K 0.237908
OSTM1 osteopetrosis associated transmembrane protein 1 0.237908
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 0.237908
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 0.237908
DEFA1B defensin, alpha 1B 0.237908
IFI30 interferon, gamma-inducible protein 30 0.237908
DCN decorin 0.237908
VMP1 vacuole membrane protein 1 0.237908
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase 0.237908
LMBRD1 LMBR1 domain containing 1 0.237908
CTSB cathepsin B 0.237908
IDUA iduronidase, alpha-L- 0.237908
LUM lumican 0.237908
CUBN cubilin (intrinsic factor-cobalamin receptor) 0.237908
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.237908
TMEM79 transmembrane protein 79 0.237908
HYAL1 hyaluronoglucosaminidase 1 0.237908
ARSA arylsulfatase A 0.237908
ARSB arylsulfatase B 0.237908
HEXA hexosaminidase A (alpha polypeptide) 0.237908
HEXB hexosaminidase B (beta polypeptide) 0.237908
OGN osteoglycin 0.237908
ANXA6 annexin A6 0.237908
SLC15A4 solute carrier family 15 (oligopeptide transporter), member 4 0.237908
AP1M2 adaptor-related protein complex 1, mu 2 subunit 0.237908
AP1M1 adaptor-related protein complex 1, mu 1 subunit 0.237908
TPP1 tripeptidyl peptidase I 0.237908
SDC4 syndecan 4 0.237908
SDC3 syndecan 3 0.237908
ANXA2 annexin A2 0.237908
SGSH N-sulfoglucosamine sulfohydrolase 0.237908
SDC1 syndecan 1 0.237908
RAB7A RAB7A, member RAS oncogene family 0.237908
ACAN aggrecan 0.237908
TCN2 transcobalamin II 0.237908
SDC2 syndecan 2 0.237908
NAGLU N-acetylglucosaminidase, alpha 0.237908
ARRB1 arrestin, beta 1 0.237908
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 0.237908
GALC galactosylceramidase 0.237908
PSEN2 presenilin 2 0.098109
PSEN1 presenilin 1 0.098109
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 0.098109
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1 0.098109
DLD dihydrolipoamide dehydrogenase 0.03318
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 0.03318
SBF2 SET binding factor 2 0.03318
ATP6V1G3 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3 0.03318
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 0.03318
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) 0.03318
LAPTM5 lysosomal protein transmembrane 5 0.03318
MTMR2 myotubularin related protein 2 0.03318
STX8 syntaxin 8 0.03318
HRG histidine-rich glycoprotein 0.03318
VAC14 Vac14 homolog (S. cerevisiae) 0.03318
RPN2 ribophorin II 0.03318
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 0.03318