uterine fibroid Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A uterine benign neoplasm derived from the smooth muscle layer of the uterus. (Human Disease Ontology, DOID_13223)
Similar Terms
Downloads & Tools

Genes

220 genes co-occuring with the disease uterine fibroid in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 1.73277
HMGA2 high mobility group AT-hook 2 1.60457
MED12 mediator complex subunit 12 1.60323
PGR progesterone receptor 1.59832
ESR1 estrogen receptor 1 1.49789
RAD51B RAD51 paralog B 1.30488
IVL involucrin 1.24385
FH fumarate hydratase 1.18066
FAM9A family with sequence similarity 9, member A 1.16563
ZSCAN12 zinc finger and SCAN domain containing 12 1.06396
NFE2L1 nuclear factor, erythroid 2-like 1 1.05135
CPXCR1 CPX chromosome region, candidate 1 1.00794
TSC2 tuberous sclerosis 2 1.00668
BOD1 biorientation of chromosomes in cell division 1 0.951187
KPNA6 karyopherin alpha 6 (importin alpha 7) 0.942443
CHRAC1 chromatin accessibility complex 1 0.939119
PCNA proliferating cell nuclear antigen 0.930414
COMT catechol-O-methyltransferase 0.915963
ISOC1 isochorismatase domain containing 1 0.91061
LHFPL3 lipoma HMGIC fusion partner-like 3 0.886389
MAP1LC3C microtubule-associated protein 1 light chain 3 gamma 0.850764
IGF1 insulin-like growth factor 1 (somatomedin C) 0.839296
VCAN versican 0.829049
DCAF5 DDB1 and CUL4 associated factor 5 0.821257
TNRC6B trinucleotide repeat containing 6B 0.813873
KLF11 Kruppel-like factor 11 0.808949
ORC5 origin recognition complex, subunit 5 0.801974
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide 0.782707
COG5 component of oligomeric golgi complex 5 0.772887
TRIP6 thyroid hormone receptor interactor 6 0.736649
CRABP2 cellular retinoic acid binding protein 2 0.732191
PCP4 Purkinje cell protein 4 0.730976
CDK19 cyclin-dependent kinase 19 0.726524
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 0.716425
PCOLCE procollagen C-endopeptidase enhancer 0.710378
VBP1 von Hippel-Lindau binding protein 1 0.707157
COX6C cytochrome c oxidase subunit VIc 0.705547
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 0.687091
MAPK12 mitogen-activated protein kinase 12 0.674713
LHFP lipoma HMGIC fusion partner 0.671925
NXF5 nuclear RNA export factor 5 0.660404
GDF10 growth differentiation factor 10 0.655254
CCNG1 cyclin G1 0.651298
KIF5C kinesin family member 5C 0.638676
TGFB3 transforming growth factor, beta 3 0.626888
FN1 fibronectin 1 0.620226
CLEC2A C-type lectin domain family 2, member A 0.617486
ESR2 estrogen receptor 2 (ER beta) 0.605372
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 0.59991
TET3 tet methylcytosine dioxygenase 3 0.59913
CALD1 caldesmon 1 0.596012
PLA2G16 phospholipase A2, group XVI 0.589001
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 0.578494
RGS7 regulator of G-protein signaling 7 0.573828
RB1 retinoblastoma 1 0.573439
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 0.570329
LAMB1 laminin, beta 1 0.552463
TAF1L TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like 0.552075
BCL2 B-cell CLL/lymphoma 2 0.541605
TSC1 tuberous sclerosis 1 0.540055
DNER delta/notch-like EGF repeat containing 0.53928
MIR363 microRNA 363 0.535409
HNRNPM heterogeneous nuclear ribonucleoprotein M 0.534248
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.522659
GLRA1 glycine receptor, alpha 1 0.50689
FMOD fibromodulin 0.506507
ARSH arylsulfatase family, member H 0.503058
LPP LIM domain containing preferred translocation partner in lipoma 0.498085
DLX6 distal-less homeobox 6 0.493503
LINC00207 long intergenic non-protein coding RNA 207 0.488549
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.486646
SPARCL1 SPARC-like 1 (hevin) 0.480945
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.479427
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 0.460883
HMGA1 high mobility group AT-hook 1 0.459373
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.443547
OXTR oxytocin receptor 0.442418
MIR217 microRNA 217 0.442042
NR2F1 nuclear receptor subfamily 2, group F, member 1 0.440162
ADM adrenomedullin 0.440162
CDK2 cyclin-dependent kinase 2 0.439786
BET1 Bet1 golgi vesicular membrane trafficking protein 0.438282
RXFP1 relaxin/insulin-like family peptide receptor 1 0.43753
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 0.436778
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma 0.43227
POLE polymerase (DNA directed), epsilon, catalytic subunit 0.426265
PEPD peptidase D 0.424389
IGF2 insulin-like growth factor 2 0.422515
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 0.417644
BAX BCL2-associated X protein 0.41727
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.415398
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.408666
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 0.407172
CRMP1 collapsin response mediator protein 1 0.404557
NCOR2 nuclear receptor corepressor 2 0.402692
AHRR aryl-hydrocarbon receptor repressor 0.400453
NCBP1 nuclear cap binding protein subunit 1, 80kDa 0.394118
RXFP2 relaxin/insulin-like family peptide receptor 2 0.387794
CDK8 cyclin-dependent kinase 8 0.384079
CCNC cyclin C 0.384079
BAG6 BCL2-associated athanogene 6 0.383708
DLEC1 deleted in lung and esophageal cancer 1 0.381852
TP63 tumor protein p63 0.377773
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 0.37629
DNTT DNA nucleotidylexotransferase 0.370737
MMP3 matrix metallopeptidase 3 0.369258
SPTB spectrin, beta, erythrocytic 0.369258
SMAD2 SMAD family member 2 0.366671
PLD1 phospholipase D1, phosphatidylcholine-specific 0.365562
CD34 CD34 molecule 0.364085
TRPC4 transient receptor potential cation channel, subfamily C, member 4 0.36187
SKI SKI proto-oncogene 0.355604
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 0.350452
VAV2 vav 2 guanine nucleotide exchange factor 0.347144
INHBA inhibin, beta A 0.344941
RAD51 RAD51 recombinase 0.342739
ACTB actin, beta 0.342739
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13 0.338707
EDNRA endothelin receptor type A 0.337608
AGTR2 angiotensin II receptor, type 2 0.33651
FLCN folliculin 0.335046
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.334315
TET1 tet methylcytosine dioxygenase 1 0.333949
EDN1 endothelin 1 0.333949
CTNNBIP1 catenin, beta interacting protein 1 0.332487
CUX1 cut-like homeobox 1 0.32774
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 0.323365
TP53 tumor protein p53 0.322273
MMP1 matrix metallopeptidase 1 0.320817
SHBG sex hormone-binding globulin 0.320817
TIMP2 TIMP metallopeptidase inhibitor 2 0.318272
TRPM6 transient receptor potential cation channel, subfamily M, member 6 0.317545
EGR1 early growth response 1 0.317182
ACTG1 actin gamma 1 0.313552
ACVR1B activin A receptor, type IB 0.309566
ZYX zyxin 0.298731
CCNB2 cyclin B2 0.298731
COL4A2 collagen, type IV, alpha 2 0.297651
PTCH2 patched 2 0.297291
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 0.296571
TGFB1 transforming growth factor, beta 1 0.288668
SMAD3 SMAD family member 3 0.286877
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.284728
S100G S100 calcium binding protein G 0.284013
S100A1 S100 calcium binding protein A1 0.284013
SOX18 SRY (sex determining region Y)-box 18 0.283655
PTGFR prostaglandin F receptor (FP) 0.283297
PCDH11X protocadherin 11 X-linked 0.283297
WNT7A wingless-type MMTV integration site family, member 7A 0.281153
ESM1 endothelial cell-specific molecule 1 0.280082
BCAN brevican 0.276514
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 0.275801
IL17B interleukin 17B 0.275801
CCND1 cyclin D1 0.275801
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.274732
DCX doublecortin 0.259124
FGF2 fibroblast growth factor 2 (basic) 0.255241
TNXB tenascin XB 0.252774
PLD2 phospholipase D2 0.251366
HDAC8 histone deacetylase 8 0.251015
TNXA tenascin XA (pseudogene) 0.246098
TXNDC9 thioredoxin domain containing 9 0.241196
DIO2 deiodinase, iodothyronine, type II 0.239799
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.239101
S100A11 S100 calcium binding protein A11 0.239101
MIR137 microRNA 137 0.238752
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa 0.237009
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.231448
GJA1 gap junction protein, alpha 1, 43kDa 0.228679
AR androgen receptor 0.223853
LIFR leukemia inhibitory factor receptor alpha 0.215314
EXO1 exonuclease 1 0.214975
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 0.214975
COL2A1 collagen, type II, alpha 1 0.212608
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.208245
DPT dermatopontin 0.207912
WISP1 WNT1 inducible signaling pathway protein 1 0.205254
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 0.203933
COL1A1 collagen, type I, alpha 1 0.201308
CTGF connective tissue growth factor 0.197742
PTHLH parathyroid hormone-like hormone 0.197099
CAPN6 calpain 6 0.194232
VEGFA vascular endothelial growth factor A 0.194232
TIMP1 TIMP metallopeptidase inhibitor 1 0.190786
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 0.18651
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.185612
CALCRL calcitonin receptor-like 0.185612
LAMB3 laminin, beta 3 0.182957
TRPC3 transient receptor potential cation channel, subfamily C, member 3 0.182957
GRB2 growth factor receptor-bound protein 2 0.182375
CYGB cytoglobin 0.180084
MAGEC1 melanoma antigen family C1 0.180084
PDGFC platelet derived growth factor C 0.176485
TRPM7 transient receptor potential cation channel, subfamily M, member 7 0.176215
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.173057
MRI1 methylthioribose-1-phosphate isomerase 1 0.172291
EBAG9 estrogen receptor binding site associated, antigen, 9 0.172291
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 0.170544
SOX4 SRY (sex determining region Y)-box 4 0.170299
YARS tyrosyl-tRNA synthetase 0.170054
CASP4 caspase 4, apoptosis-related cysteine peptidase 0.170054
RHAG Rh-associated glycoprotein 0.168148
MMP2 matrix metallopeptidase 2 0.168148
CCR4 chemokine (C-C motif) receptor 4 0.168148
TGFA transforming growth factor, alpha 0.166319
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.166319
BSG basigin (Ok blood group) 0.165001
TRPC1 transient receptor potential cation channel, subfamily C, member 1 0.164359
AKAP13 A kinase (PRKA) anchor protein 13 0.163111
SEPT5 septin 5 0.162505
IGFBP6 insulin-like growth factor binding protein 6 0.161331
EBF1 early B-cell factor 1 0.160761
FOS FBJ murine osteosarcoma viral oncogene homolog 0.160761
SPHK1 sphingosine kinase 1 0.159838
MYF5 myogenic factor 5 0.159302
MCF2 MCF.2 cell line derived transforming sequence 0.159302
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.159124
GFER growth factor, augmenter of liver regeneration 0.158951
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 0.157929
SELENBP1 selenium binding protein 1 0.157929