uterine endometrial cancer cell Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description More than 95% of uterine cancers arise in the endometrium. Endometrial cancer develops when the cells that make up the endometrium become abnormal and grow uncontrollably. (BRENDA Tissue and Enzyme Source Ontology, BTO_0003871)
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Genes

167 proteins co-occuring with the tissue uterine endometrial cancer cell in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
ESR1 estrogen receptor 1 1.79701
PGR progesterone receptor 1.37864
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.37682
PTEN phosphatase and tensin homolog 1.33636
GPER1 G protein-coupled estrogen receptor 1 1.30568
COPZ2 coatomer protein complex, subunit zeta 2 1.20867
CGRRF1 cell growth regulator with ring finger domain 1 1.19489
CDC42SE2 CDC42 small effector 2 1.09253
GNRH2 gonadotropin-releasing hormone 2 1.09208
ESR2 estrogen receptor 2 (ER beta) 1.08457
CCND1 cyclin D1 1.07221
RB1 retinoblastoma 1 1.01243
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.991944
TP53 tumor protein p53 0.928478
GLO1 glyoxalase I 0.916069
CRELD1 cysteine-rich with EGF-like domains 1 0.856732
HDAC9 histone deacetylase 9 0.856732
TNS1 tensin 1 0.846644
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.846644
ARHGAP19 Rho GTPase activating protein 19 0.816486
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6 0.806047
BAX BCL2-associated X protein 0.804378
IGFBP3 insulin-like growth factor binding protein 3 0.794792
TUBB4B tubulin, beta 4B class IVb 0.789796
PPME1 protein phosphatase methylesterase 1 0.781478
HINT2 histidine triad nucleotide binding protein 2 0.769855
IGF1 insulin-like growth factor 1 (somatomedin C) 0.766539
PAEP progestagen-associated endometrial protein 0.727741
EMP2 epithelial membrane protein 2 0.725274
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 0.701899
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.697808
AKT2 v-akt murine thymoma viral oncogene homolog 2 0.690042
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 0.688817
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha 0.688
AGR3 anterior gradient 3 0.684735
TYMP thymidine phosphorylase 0.677803
THEMIS2 thymocyte selection associated family member 2 0.668843
MTDH metadherin 0.667215
MMP2 matrix metallopeptidase 2 0.65746
MACROD1 MACRO domain containing 1 0.642048
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 0.631527
FOXO1 forkhead box O1 0.625061
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 0.615377
TERT telomerase reverse transcriptase 0.614974
FGFR2 fibroblast growth factor receptor 2 0.613764
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.602088
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1 0.601686
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor 0.600479
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.595255
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.593649
TP53AIP1 tumor protein p53 regulated apoptosis inducing protein 1 0.590036
HIST1H1E histone cluster 1, H1e 0.57082
AHR aryl hydrocarbon receptor 0.567227
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.546136
SLC2A14 solute carrier family 2 (facilitated glucose transporter), member 14 0.541377
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.539396
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.527139
MAPK3 mitogen-activated protein kinase 3 0.520829
BRD7 bromodomain containing 7 0.512564
HPN hepsin 0.512171
PLXNA3 plexin A3 0.507457
PCNA proliferating cell nuclear antigen 0.50275
MLH1 mutL homolog 1 0.501574
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.499223
CTSD cathepsin D 0.496483
LEPR leptin receptor 0.493354
CDC25C cell division cycle 25C 0.491791
EGLN1 egl-9 family hypoxia-inducible factor 1 0.489447
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.488276
FGF2 fibroblast growth factor 2 (basic) 0.485935
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.482428
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial 0.479312
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6 0.471927
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 0.464948
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 0.459532
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.457987
CDK4 cyclin-dependent kinase 4 0.450271
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 0.448346
SRSF5 serine/arginine-rich splicing factor 5 0.444499
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.442578
WEE1 WEE1 G2 checkpoint kinase 0.437972
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.436438
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.428401
PDCD10 programmed cell death 10 0.422292
G0S2 G0/G1 switch 2 0.419623
SLC25A27 solute carrier family 25, member 27 0.418099
SRSF3 serine/arginine-rich splicing factor 3 0.418099
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 0.412391
CDK8 cyclin-dependent kinase 8 0.399871
MCM4 minichromosome maintenance complex component 4 0.397222
FAM195A family with sequence similarity 195, member A 0.396844
ZEB2 zinc finger E-box binding homeobox 2 0.396087
JUN jun proto-oncogene 0.395331
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 0.390421
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.389289
LEP leptin 0.384766
MT1E metallothionein 1E 0.384013
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 0.375743
ANTXR2 anthrax toxin receptor 2 0.375743
PELP1 proline, glutamate and leucine rich protein 1 0.374243
BIRC5 baculoviral IAP repeat containing 5 0.369373
ANXA5 annexin A5 0.366754
IGF1R insulin-like growth factor 1 receptor 0.366007
ERAP1 endoplasmic reticulum aminopeptidase 1 0.362646
FOS FBJ murine osteosarcoma viral oncogene homolog 0.362273
CYR61 cysteine-rich, angiogenic inducer, 61 0.361155
FAXDC2 fatty acid hydroxylase domain containing 2 0.356686
NCOA3 nuclear receptor coactivator 3 0.348889
FZD10 frizzled class receptor 10 0.345558
TYK2 tyrosine kinase 2 0.342233
KSR1 kinase suppressor of ras 1 0.330827
FZD5 frizzled class receptor 5 0.329727
PIAS3 protein inhibitor of activated STAT, 3 0.325701
PPIA peptidylprolyl isomerase A (cyclophilin A) 0.324605
KDM6A lysine (K)-specific demethylase 6A 0.322414
STS steroid sulfatase (microsomal), isozyme S 0.318042
HOXB13 homeobox B13 0.315861
MMP9 matrix metallopeptidase 9 0.309335
HEATR6 HEAT repeat containing 6 0.303559
PARP1 poly (ADP-ribose) polymerase 1 0.302478
MIR203A microRNA 203a 0.298883
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 0.296013
RBL2 retinoblastoma-like 2 0.294223
NRIP1 nuclear receptor interacting protein 1 0.289939
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 0.281776
CCNG1 cyclin G1 0.279307
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 0.276145
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.275444
ERBB2 erb-b2 receptor tyrosine kinase 2 0.274045
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 0.271604
IL11 interleukin 11 0.270561
BMI1 BMI1 proto-oncogene, polycomb ring finger 0.270214
HRAS Harvey rat sarcoma viral oncogene homolog 0.269521
PCCA propionyl CoA carboxylase, alpha polypeptide 0.261964
BRD4 bromodomain containing 4 0.261284
PLXNA1 plexin A1 0.259591
ZEB1 zinc finger E-box binding homeobox 1 0.257237
BIRC3 baculoviral IAP repeat containing 3 0.2559
CCNE2 cyclin E2 0.255567
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.247079
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 0.246442
IFNB1 interferon, beta 1, fibroblast 0.245807
MSH2 mutS homolog 2 0.245491
CHEK1 checkpoint kinase 1 0.242054
GNRHR gonadotropin-releasing hormone receptor 0.24052
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.239007
HSD17B1P1 hydroxysteroid (17-beta) dehydrogenase 1 pseudogene 1 0.238406
HECA headcase homolog (Drosophila) 0.237513
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 0.236921
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 0.232317
ITGA1 integrin, alpha 1 0.23176
FGF4 fibroblast growth factor 4 0.229299
SFRP4 secreted frizzled-related protein 4 0.226926
GPBAR1 G protein-coupled bile acid receptor 1 0.226926
SPINT1 serine peptidase inhibitor, Kunitz type 1 0.225647
CCNE1 cyclin E1 0.225395
EGFR epidermal growth factor receptor 0.224645
KRAS Kirsten rat sarcoma viral oncogene homolog 0.221521
ZHX2 zinc fingers and homeoboxes 2 0.221521
NR1I2 nuclear receptor subfamily 1, group I, member 2 0.219047
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 0.217762
BAD BCL2-associated agonist of cell death 0.217554
ARHGAP35 Rho GTPase activating protein 35 0.21673
LGMN legumain 0.216325
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.214954
FOXC1 forkhead box C1 0.214202
PPARG peroxisome proliferator-activated receptor gamma 0.213471