ursolic acid-7181 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the ursolic acid-7181 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AEN apoptosis enhancing nuclease
AKAP7 A kinase (PRKA) anchor protein 7
AKR1C2 aldo-keto reductase family 1, member C2
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ANKMY1 ankyrin repeat and MYND domain containing 1
ARHGAP35 Rho GTPase activating protein 35
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATXN7L3B ataxin 7-like 3B
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
BST2 bone marrow stromal cell antigen 2
CACYBP calcyclin binding protein
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CAPG capping protein (actin filament), gelsolin-like
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCDC88A coiled-coil domain containing 88A
CD44 CD44 molecule (Indian blood group)
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CLCN4 chloride channel, voltage-sensitive 4
COL14A1 collagen, type XIV, alpha 1
COPA coatomer protein complex, subunit alpha
CTNS cystinosin, lysosomal cystine transporter
DEGS1 delta(4)-desaturase, sphingolipid 1
DENND4A DENN/MADD domain containing 4A
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
ELSPBP1 epididymal sperm binding protein 1
FLJ11292
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GMEB1 glucocorticoid modulatory element binding protein 1
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMGN5 high mobility group nucleosome binding domain 5
IFI27 interferon, alpha-inducible protein 27
IFI35 interferon-induced protein 35
IFI6 interferon, alpha-inducible protein 6
IFIH1 interferon induced with helicase C domain 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
INCENP inner centromere protein antigens 135/155kDa
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
IRF9 interferon regulatory factor 9
ISG15 ISG15 ubiquitin-like modifier
ITM2B integral membrane protein 2B
JAKMIP2 janus kinase and microtubule interacting protein 2
KITLG KIT ligand
KRIT1 KRIT1, ankyrin repeat containing
LPCAT3 lysophosphatidylcholine acyltransferase 3
LPXN leupaxin
LYPD1 LY6/PLAUR domain containing 1
MAN1A1 mannosidase, alpha, class 1A, member 1
MAPK8 mitogen-activated protein kinase 8
MET MET proto-oncogene, receptor tyrosine kinase
MID2 midline 2
MMP3 matrix metallopeptidase 3
MORC3 MORC family CW-type zinc finger 3
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NXT2 nuclear transport factor 2-like export factor 2
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PAPOLA poly(A) polymerase alpha
PARD6B par-6 family cell polarity regulator beta
PARP12 poly (ADP-ribose) polymerase family, member 12
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PLSCR1 phospholipid scramblase 1
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PROSC proline synthetase co-transcribed homolog (bacterial)
PTBP3 polypyrimidine tract binding protein 3
QKI QKI, KH domain containing, RNA binding
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RCAN1 regulator of calcineurin 1
RHOQ ras homolog family member Q
RINT1 RAD50 interactor 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SAMD9 sterile alpha motif domain containing 9
SH3BP2 SH3-domain binding protein 2
SKIL SKI-like proto-oncogene
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOAT1 sterol O-acyltransferase 1
SOX4 SRY (sex determining region Y)-box 4
SP100 SP100 nuclear antigen
SP110 SP110 nuclear body protein
SPATA5L1 spermatogenesis associated 5-like 1
SRPR signal recognition particle receptor (docking protein)
STAT1 signal transducer and activator of transcription 1, 91kDa
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TANK TRAF family member-associated NFKB activator
TMPO thymopoietin
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TPD52 tumor protein D52
TRA2A transformer 2 alpha homolog (Drosophila)
TRAPPC13 trafficking protein particle complex 13
TRIM14 tripartite motif containing 14
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ACIN1 apoptotic chromatin condensation inducer 1
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
AGBL5 ATP/GTP binding protein-like 5
AHDC1 AT hook, DNA binding motif, containing 1
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ATAD5 ATPase family, AAA domain containing 5
BBC3 BCL2 binding component 3
BRD9 bromodomain containing 9
C14ORF132 chromosome 14 open reading frame 132
CAPN15 calpain 15
CASZ1 castor zinc finger 1
CBX4 chromobox homolog 4
CCDC9 coiled-coil domain containing 9
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CFD complement factor D (adipsin)
CHKB choline kinase beta
CLSPN claspin
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CRYL1 crystallin, lambda 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DGAT1 diacylglycerol O-acyltransferase 1
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FAM53B family with sequence similarity 53, member B
FCHO1 FCH domain only 1
FKBP10 FK506 binding protein 10, 65 kDa
FKBP14 FK506 binding protein 14, 22 kDa
FRS2 fibroblast growth factor receptor substrate 2
FZD4 frizzled class receptor 4
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GOLGA3 golgin A3
GPATCH1 G patch domain containing 1
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
H2AFJ H2A histone family, member J
HIST1H2BO histone cluster 1, H2bo
HLA-J major histocompatibility complex, class I, J (pseudogene)
HOXC13 homeobox C13
IRF1 interferon regulatory factor 1
KLF11 Kruppel-like factor 11
LHX1 LIM homeobox 1
LIN7B lin-7 homolog B (C. elegans)
LMCD1 LIM and cysteine-rich domains 1
LMNB2 lamin B2
LRP3 low density lipoprotein receptor-related protein 3
LRRC49 leucine rich repeat containing 49
LY6D lymphocyte antigen 6 complex, locus D
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAMLD1 mastermind-like domain containing 1
MAST3 microtubule associated serine/threonine kinase 3
MKS1 Meckel syndrome, type 1
MNX1 motor neuron and pancreas homeobox 1
MXD3 MAX dimerization protein 3
NBAS neuroblastoma amplified sequence
OGFRL1 opioid growth factor receptor-like 1
ORAI3 ORAI calcium release-activated calcium modulator 3
OTUD3 OTU deubiquitinase 3
PDLIM2 PDZ and LIM domain 2 (mystique)
PDZRN3 PDZ domain containing ring finger 3
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLD3 phospholipase D family, member 3
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PPT2 palmitoyl-protein thioesterase 2
PRICKLE3 prickle homolog 3 (Drosophila)
PYCRL pyrroline-5-carboxylate reductase-like
RNF123 ring finger protein 123
RPAP2 RNA polymerase II associated protein 2
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SDC3 syndecan 3
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SH2D4A SH2 domain containing 4A
SH3GL1 SH3-domain GRB2-like 1
SLC12A8 solute carrier family 12, member 8
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SOX3 SRY (sex determining region Y)-box 3
SPATA7 spermatogenesis associated 7
SYCP2 synaptonemal complex protein 2
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TBC1D13 TBC1 domain family, member 13
TLR5 toll-like receptor 5
TMC5 transmembrane channel-like 5
TMEM39B transmembrane protein 39B
TMUB2 transmembrane and ubiquitin-like domain containing 2
TNK1 tyrosine kinase, non-receptor, 1
TNS2 tensin 2
TSPAN14 tetraspanin 14
TTC30A tetratricopeptide repeat domain 30A
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
URGCP upregulator of cell proliferation
VASH2 vasohibin 2
VPS9D1 VPS9 domain containing 1
WDR13 WD repeat domain 13
ZBED1 zinc finger, BED-type containing 1
ZDHHC18 zinc finger, DHHC-type containing 18
ZFP36 ZFP36 ring finger protein
ZNF778 zinc finger protein 778
ZNHIT2 zinc finger, HIT-type containing 2