ursolic acid-2230 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the ursolic acid-2230 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVR1B activin A receptor, type IB
ADGRA2 adhesion G protein-coupled receptor A2
AKR1C1 aldo-keto reductase family 1, member C1
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
AQP3 aquaporin 3 (Gill blood group)
ARPIN actin-related protein 2/3 complex inhibitor
ATF3 activating transcription factor 3
BHLHE40 basic helix-loop-helix family, member e40
BIRC3 baculoviral IAP repeat containing 3
CASP2 caspase 2, apoptosis-related cysteine peptidase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CEMIP cell migration inducing protein, hyaluronan binding
CFLAR CASP8 and FADD-like apoptosis regulator
COL17A1 collagen, type XVII, alpha 1
COL19A1 collagen, type XIX, alpha 1
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CTBP2 C-terminal binding protein 2
CTNS cystinosin, lysosomal cystine transporter
DAPK1 death-associated protein kinase 1
DOPEY2 dopey family member 2
DUSP4 dual specificity phosphatase 4
EGFR epidermal growth factor receptor
EGR1 early growth response 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FOS FBJ murine osteosarcoma viral oncogene homolog
GEM GTP binding protein overexpressed in skeletal muscle
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLB1L galactosidase, beta 1-like
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GOLGA8A golgin A8 family, member A
GUSBP3 glucuronidase, beta pseudogene 3
HFE hemochromatosis
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0
ICAM1 intercellular adhesion molecule 1
IL6ST interleukin 6 signal transducer
INHBE inhibin, beta E
INSIG1 insulin induced gene 1
ISG20 interferon stimulated exonuclease gene 20kDa
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
JAG1 jagged 1
JUN jun proto-oncogene
KLF2 Kruppel-like factor 2
KLF6 Kruppel-like factor 6
KLHL20 kelch-like family member 20
KLHL24 kelch-like family member 24
LIF leukemia inhibitory factor
LPIN1 lipin 1
LYST lysosomal trafficking regulator
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MALL mal, T-cell differentiation protein-like
MBNL2 muscleblind-like splicing regulator 2
MECOM MDS1 and EVI1 complex locus
MED18 mediator complex subunit 18
MEX3D mex-3 RNA binding family member D
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MIP major intrinsic protein of lens fiber
MKL1 megakaryoblastic leukemia (translocation) 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NID1 nidogen 1
NIPAL3 NIPA-like domain containing 3
OAZ3 ornithine decarboxylase antizyme 3
OMD osteomodulin
PARD6B par-6 family cell polarity regulator beta
PARP3 poly (ADP-ribose) polymerase family, member 3
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PHLDA1 pleckstrin homology-like domain, family A, member 1
PKNOX2 PBX/knotted 1 homeobox 2
PLCB2 phospholipase C, beta 2
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PSD3 pleckstrin and Sec7 domain containing 3
PTPN12 protein tyrosine phosphatase, non-receptor type 12
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RND1 Rho family GTPase 1
SERHL2 serine hydrolase-like 2
SFTPC surfactant protein C
SKIL SKI-like proto-oncogene
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
T T, brachyury homolog (mouse)
TEP1 telomerase-associated protein 1
TGFB2 transforming growth factor, beta 2
TIMP3 TIMP metallopeptidase inhibitor 3
TMEM209 transmembrane protein 209
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TRIM29 tripartite motif containing 29
TWF1 twinfilin actin binding protein 1
WNK1 WNK lysine deficient protein kinase 1
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
YPEL1 yippee-like 1 (Drosophila)
ZMYND8 zinc finger, MYND-type containing 8
ZNF652 zinc finger protein 652

decreased expression

Symbol Name
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARMCX2 armadillo repeat containing, X-linked 2
ARRB1 arrestin, beta 1
AUP1 ancient ubiquitous protein 1
BAHCC1 BAH domain and coiled-coil containing 1
BCL7B B-cell CLL/lymphoma 7B
BTBD2 BTB (POZ) domain containing 2
C11ORF80 chromosome 11 open reading frame 80
C1QTNF3 C1q and tumor necrosis factor related protein 3
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CCNE1 cyclin E1
CCP110 centriolar coiled coil protein 110kDa
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CENPT centromere protein T
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CRIP1 cysteine-rich protein 1 (intestinal)
CUL9 cullin 9
DPY19L1P1 DPY19L1 pseudogene 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
DYSF dysferlin
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ELOVL4 ELOVL fatty acid elongase 4
ELSPBP1 epididymal sperm binding protein 1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ETNK2 ethanolamine kinase 2
FBXL7 F-box and leucine-rich repeat protein 7
FOXD1 forkhead box D1
FSD1 fibronectin type III and SPRY domain containing 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GADD45G growth arrest and DNA-damage-inducible, gamma
GAMT guanidinoacetate N-methyltransferase
GATA4 GATA binding protein 4
HCFC2 host cell factor C2
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H3B histone cluster 1, H3b
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITPKB inositol-trisphosphate 3-kinase B
KIAA0319L KIAA0319-like
KRT15 keratin 15, type I
LIN7A lin-7 homolog A (C. elegans)
LY6D lymphocyte antigen 6 complex, locus D
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAPKBP1 mitogen-activated protein kinase binding protein 1
MGC12488
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYOZ1 myozenin 1
NABP2 nucleic acid binding protein 2
NLRX1 NLR family member X1
NOD1 nucleotide-binding oligomerization domain containing 1
NPFFR1 neuropeptide FF receptor 1
NPM3 nucleophosmin/nucleoplasmin 3
NT5DC3 5'-nucleotidase domain containing 3
NXPH4 neurexophilin 4
OLFML2A olfactomedin-like 2A
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PACS1 phosphofurin acidic cluster sorting protein 1
PAIP2B poly(A) binding protein interacting protein 2B
PALM paralemmin
PCDHB8 protocadherin beta 8
PHC1 polyhomeotic homolog 1 (Drosophila)
PKN1 protein kinase N1
POLL polymerase (DNA directed), lambda
PRICKLE3 prickle homolog 3 (Drosophila)
RAB5C RAB5C, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RANGRF RAN guanine nucleotide release factor
RCAN3 RCAN family member 3
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RHBDD3 rhomboid domain containing 3
RPAP1 RNA polymerase II associated protein 1
RPAP2 RNA polymerase II associated protein 2
RPGRIP1L RPGRIP1-like
SAYSD1 SAYSVFN motif domain containing 1
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TEX40 testis expressed 40
TICAM1 toll-like receptor adaptor molecule 1
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TM6SF1 transmembrane 6 superfamily member 1
TMCC2 transmembrane and coiled-coil domain family 2
TMLHE trimethyllysine hydroxylase, epsilon
TNS2 tensin 2
TUBA3C tubulin, alpha 3c
UNC119 unc-119 homolog (C. elegans)
VEGFB vascular endothelial growth factor B
WDR33 WD repeat domain 33
WFDC2 WAP four-disulfide core domain 2
XYLT2 xylosyltransferase II
ZGPAT zinc finger, CCCH-type with G patch domain
ZNF205 zinc finger protein 205
ZNF37BP zinc finger protein 37B, pseudogene