ursolic acid-2067 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the ursolic acid-2067 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4
ADCY1 adenylate cyclase 1 (brain)
ADRBK1 adrenergic, beta, receptor kinase 1
ADRBK2 adrenergic, beta, receptor kinase 2
AKAP13 A kinase (PRKA) anchor protein 13
ALK anaplastic lymphoma receptor tyrosine kinase
ANGPTL4 angiopoietin-like 4
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ASAP1-IT1 ASAP1 intronic transcript 1
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BMP4 bone morphogenetic protein 4
C1QL1 complement component 1, q subcomponent-like 1
CCNJ cyclin J
CCR7 chemokine (C-C motif) receptor 7
CHI3L2 chitinase 3-like 2
COL6A1 collagen, type VI, alpha 1
CPA4 carboxypeptidase A4
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
DEAF1 DEAF1 transcription factor
DHODH dihydroorotate dehydrogenase (quinone)
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
EDNRA endothelin receptor type A
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
EML2 echinoderm microtubule associated protein like 2
F11R F11 receptor
FAM178A family with sequence similarity 178, member A
FCMR Fc fragment of IgM receptor
FOXO1 forkhead box O1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GNPDA1 glucosamine-6-phosphate deaminase 1
GPR4 G protein-coupled receptor 4
HMOX1 heme oxygenase 1
HOOK1 hook microtubule-tethering protein 1
IGF1R insulin-like growth factor 1 receptor
IGFBP5 insulin-like growth factor binding protein 5
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
ING4 inhibitor of growth family, member 4
INSIG1 insulin induced gene 1
ITPKC inositol-trisphosphate 3-kinase C
JUN jun proto-oncogene
KDM5A lysine (K)-specific demethylase 5A
KIAA1644 KIAA1644
KIF1C kinesin family member 1C
KPNA5 karyopherin alpha 5 (importin alpha 6)
KRT75 keratin 75, type II
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LARGE like-glycosyltransferase
LDLR low density lipoprotein receptor
LRP2 low density lipoprotein receptor-related protein 2
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LRRN2 leucine rich repeat neuronal 2
MANBA mannosidase, beta A, lysosomal
MBTD1 mbt domain containing 1
MEF2A myocyte enhancer factor 2A
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MSL3 male-specific lethal 3 homolog (Drosophila)
MUC1 mucin 1, cell surface associated
MYRF myelin regulatory factor
NCAPH2 non-SMC condensin II complex, subunit H2
NF2 neurofibromin 2 (merlin)
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NKX3-2 NK3 homeobox 2
NMT2 N-myristoyltransferase 2
NUCB1 nucleobindin 1
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PSENEN presenilin enhancer gamma secretase subunit
RIN1 Ras and Rab interactor 1
RPGRIP1L RPGRIP1-like
RPL23 ribosomal protein L23
RPLP2 ribosomal protein, large, P2
SCGB2A2 secretoglobin, family 2A, member 2
SLC17A2 solute carrier family 17, member 2
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SP100 SP100 nuclear antigen
SPHK2 sphingosine kinase 2
SQLE squalene epoxidase
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
TBC1D30 TBC1 domain family, member 30
TRA2A transformer 2 alpha homolog (Drosophila)
TRIM29 tripartite motif containing 29
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
USP27X ubiquitin specific peptidase 27, X-linked
VWA1 von Willebrand factor A domain containing 1
VWA8 von Willebrand factor A domain containing 8
WDR4 WD repeat domain 4
ZMYM2 zinc finger, MYM-type 2
ZNF117 zinc finger protein 117
ZNF385D zinc finger protein 385D

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ADCY6 adenylate cyclase 6
APOLD1 apolipoprotein L domain containing 1
ARID4A AT rich interactive domain 4A (RBP1-like)
ARRB2 arrestin, beta 2
AUH AU RNA binding protein/enoyl-CoA hydratase
AURKB aurora kinase B
AXIN1 axin 1
BACE1 beta-site APP-cleaving enzyme 1
BAHD1 bromo adjacent homology domain containing 1
BCL9 B-cell CLL/lymphoma 9
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BLMH bleomycin hydrolase
C1ORF56 chromosome 1 open reading frame 56
CAMTA2 calmodulin binding transcription activator 2
CHMP6 charged multivesicular body protein 6
CLASP1 cytoplasmic linker associated protein 1
CLEC16A C-type lectin domain family 16, member A
CNGB3 cyclic nucleotide gated channel beta 3
CPEB1 cytoplasmic polyadenylation element binding protein 1
CRYBA2 crystallin, beta A2
CST4 cystatin S
CXORF56 chromosome X open reading frame 56
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DMTF1 cyclin D binding myb-like transcription factor 1
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
EPN3 epsin 3
EPPK1 epiplakin 1
ERF Ets2 repressor factor
FBXO2 F-box protein 2
FGD1 FYVE, RhoGEF and PH domain containing 1
GAMT guanidinoacetate N-methyltransferase
GDAP2 ganglioside induced differentiation associated protein 2
GLI3 GLI family zinc finger 3
GLT8D2 glycosyltransferase 8 domain containing 2
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPR176 G protein-coupled receptor 176
GUF1 GUF1 GTPase homolog (S. cerevisiae)
HDAC7 histone deacetylase 7
HOXC10 homeobox C10
HSPB8 heat shock 22kDa protein 8
ILK integrin-linked kinase
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA0232 KIAA0232
KIAA0753 KIAA0753
KRT4 keratin 4, type II
MAST3 microtubule associated serine/threonine kinase 3
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MFSD12 major facilitator superfamily domain containing 12
MOGS mannosyl-oligosaccharide glucosidase
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
NPM3 nucleophosmin/nucleoplasmin 3
NR1H2 nuclear receptor subfamily 1, group H, member 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
NT5DC3 5'-nucleotidase domain containing 3
NT5E 5'-nucleotidase, ecto (CD73)
NT5M 5',3'-nucleotidase, mitochondrial
NUBP2 nucleotide binding protein 2
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
OCEL1 occludin/ELL domain containing 1
ORAI3 ORAI calcium release-activated calcium modulator 3
PAQR4 progestin and adipoQ receptor family member IV
PARD6A par-6 family cell polarity regulator alpha
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLEKHO2 pleckstrin homology domain containing, family O member 2
POMT2 protein-O-mannosyltransferase 2
PPP2R2D protein phosphatase 2, regulatory subunit B, delta
PROSER1 proline and serine rich 1
PSAT1 phosphoserine aminotransferase 1
RAB17 RAB17, member RAS oncogene family
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae)
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF25 ring finger protein 25
SCML2 sex comb on midleg-like 2 (Drosophila)
SEC14L2 SEC14-like 2 (S. cerevisiae)
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SESN1 sestrin 1
SH2D2A SH2 domain containing 2A
SNPH syntaphilin
SPEG SPEG complex locus
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STK16 serine/threonine kinase 16
STX5 syntaxin 5
TIMP4 TIMP metallopeptidase inhibitor 4
TPCN1 two pore segment channel 1
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TTC23 tetratricopeptide repeat domain 23
USP18 ubiquitin specific peptidase 18
YEATS4 YEATS domain containing 4
ZFYVE16 zinc finger, FYVE domain containing 16
ZNF232 zinc finger protein 232
ZNF701 zinc finger protein 701