ursodeoxycholic acid_mus musculus_gpl8321_gse21266 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule]_[organism]_[GEO platform]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE21266
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Genes

128 genes differentially expressed following the ursodeoxycholic acid_mus musculus_gpl8321_gse21266 small molecule perturbation from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
AHNAK AHNAK nucleoprotein
ARL4A ADP-ribosylation factor-like 4A
ATF3 activating transcription factor 3
BTG2 BTG family, member 2
CA2 carbonic anhydrase II
CA4 carbonic anhydrase IV
CCND2 cyclin D2
CLDN8 claudin 8
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18
DMBT1 deleted in malignant brain tumors 1
EGR1 early growth response 1
FXYD4 FXYD domain containing ion transport regulator 4
H1F0 H1 histone family, member 0
H3F3B H3 histone, family 3B (H3.3B)
HIST1H1C histone cluster 1, H1c
HIST1H2BC histone cluster 1, H2bc
HIST1H2BH histone cluster 1, H2bh
IER2 immediate early response 2
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL18 interleukin 18
ISG15 ISG15 ubiquitin-like modifier
IVNS1ABP influenza virus NS1A binding protein
JUN jun proto-oncogene
KLF4 Kruppel-like factor 4 (gut)
KLF6 Kruppel-like factor 6
KRT18 keratin 18, type I
LGALS9 lectin, galactoside-binding, soluble, 9
NR4A1 nuclear receptor subfamily 4, group A, member 1
NUPR1 nuclear protein, transcriptional regulator, 1
PIGR polymeric immunoglobulin receptor
PMP22 peripheral myelin protein 22
RHOB ras homolog family member B
RSAD2 radical S-adenosyl methionine domain containing 2
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
SYCN syncollin
TGM3 transglutaminase 3
THBS1 thrombospondin 1
TXNIP thioredoxin interacting protein
UBC ubiquitin C
WFDC2 WAP four-disulfide core domain 2
XIST X inactive specific transcript (non-protein coding)
ZFAND5 zinc finger, AN1-type domain 5
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
ACTB actin, beta
AGR2 anterior gradient 2
ALDOA aldolase A, fructose-bisphosphate
ANXA4 annexin A4
AQP8 aquaporin 8
ATP5I ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E
CALM1 calmodulin 1 (phosphorylase kinase, delta)
COX4I1 cytochrome c oxidase subunit IV isoform 1
COX6C cytochrome c oxidase subunit VIc
CYC1 cytochrome c-1
CYCS cytochrome c, somatic
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DYNLL1 dynein, light chain, LC8-type 1
EIF1 eukaryotic translation initiation factor 1
EIF4A1 eukaryotic translation initiation factor 4A1
EIF5A eukaryotic translation initiation factor 5A
ENO1 enolase 1, (alpha)
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GPX2 glutathione peroxidase 2
GSTA5 glutathione S-transferase alpha 5
HIGD1A HIG1 hypoxia inducible domain family, member 1A
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA1B heat shock 70kDa protein 1B
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA8 heat shock 70kDa protein 8
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPH1 heat shock 105kDa/110kDa protein 1
INSL5 insulin-like 5
KLK1 kallikrein 1
KRT19 keratin 19, type I
LDHA lactate dehydrogenase A
MANF mesencephalic astrocyte-derived neurotrophic factor
MDH1 malate dehydrogenase 1, NAD (soluble)
MDH2 malate dehydrogenase 2, NAD (mitochondrial)
MGST1 microsomal glutathione S-transferase 1
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MRPL12 mitochondrial ribosomal protein L12
MTMR11 myotubularin related protein 11
NDUFA11 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa
NME1 NME/NM23 nucleoside diphosphate kinase 1
PFN1 profilin 1
PGAM1 phosphoglycerate mutase 1 (brain)
PGK1 phosphoglycerate kinase 1
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PRELID1 PRELI domain containing 1
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PYY peptide YY
REG4 regenerating islet-derived family, member 4
RETNLB resistin like beta
RPL10 ribosomal protein L10
RPL13A ribosomal protein L13a
RPL14 ribosomal protein L14
RPL18 ribosomal protein L18
RPL35 ribosomal protein L35
RPL37 ribosomal protein L37
RPL7 ribosomal protein L7
RPS17 ribosomal protein S17
RPS18 ribosomal protein S18
RPS8 ribosomal protein S8
S100A10 S100 calcium binding protein A10
S100G S100 calcium binding protein G
SAA2 serum amyloid A2
SAMM50 SAMM50 sorting and assembly machinery component
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCD5 stearoyl-CoA desaturase 5
SEPP1 selenoprotein P, plasma, 1
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
SLPI secretory leukocyte peptidase inhibitor
SPINK1 serine peptidase inhibitor, Kazal type 1
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
TFRC transferrin receptor
TMA7 translation machinery associated 7 homolog (S. cerevisiae)
TMIGD1 transmembrane and immunoglobulin domain containing 1
TMSB10 thymosin beta 10
TPI1 triosephosphate isomerase 1
UQCRH ubiquinol-cytochrome c reductase hinge protein
YBX3 Y box binding protein 3
ZG16 zymogen granule protein 16
ZNF526 zinc finger protein 526