ursodeoxycholic acid_mus musculus_gpl8321_gds4372 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule]_[organism]_[GEO platform]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GDS4372
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131 genes differentially expressed following the ursodeoxycholic acid_mus musculus_gpl8321_gds4372 small molecule perturbation from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGR2 anterior gradient 2
ALDOA aldolase A, fructose-bisphosphate
CALR calreticulin
COX6C cytochrome c oxidase subunit VIc
CYCS cytochrome c, somatic
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DYNLL1 dynein, light chain, LC8-type 1
ENO1 enolase 1, (alpha)
GPX2 glutathione peroxidase 2
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
INSL5 insulin-like 5
KRT19 keratin 19, type I
LDHA lactate dehydrogenase A
MDH1 malate dehydrogenase 1, NAD (soluble)
MDH2 malate dehydrogenase 2, NAD (mitochondrial)
MGST1 microsomal glutathione S-transferase 1
MPTX1 mucosal pentraxin 1 (pseudogene)
PFN1 profilin 1
PGK1 phosphoglycerate kinase 1
PRELID1 PRELI domain containing 1
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
REG4 regenerating islet-derived family, member 4
RETNLB resistin like beta
RPL7 ribosomal protein L7
RPS17 ribosomal protein S17
RPS8 ribosomal protein S8
S100A10 S100 calcium binding protein A10
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCD5 stearoyl-CoA desaturase 5
SEPP1 selenoprotein P, plasma, 1
SLPI secretory leukocyte peptidase inhibitor
SPINK1 serine peptidase inhibitor, Kazal type 1
TFRC transferrin receptor
TPI1 triosephosphate isomerase 1
UQCRH ubiquinol-cytochrome c reductase hinge protein
ZG16 zymogen granule protein 16
ZNF526 zinc finger protein 526

decreased expression

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACLY ATP citrate lyase
AHNAK AHNAK nucleoprotein
AREG amphiregulin
ARL4A ADP-ribosylation factor-like 4A
ATF3 activating transcription factor 3
ATF4 activating transcription factor 4
BTG2 BTG family, member 2
CA2 carbonic anhydrase II
CA4 carbonic anhydrase IV
CCND2 cyclin D2
CCNI cyclin I
CD9 CD9 molecule
CLDN3 claudin 3
CLDN8 claudin 8
CXCL10 chemokine (C-X-C motif) ligand 10
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18
DMBT1 deleted in malignant brain tumors 1
DUSP1 dual specificity phosphatase 1
EGR1 early growth response 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FXYD4 FXYD domain containing ion transport regulator 4
GLUL glutamate-ammonia ligase
GSDMC gasdermin C
GSN gelsolin
H1F0 H1 histone family, member 0
H3F3B H3 histone, family 3B (H3.3B)
HAO2 hydroxyacid oxidase 2 (long chain)
HBEGF heparin-binding EGF-like growth factor
HIST1H1C histone cluster 1, H1c
HIST1H2BC histone cluster 1, H2bc
HIST1H2BH histone cluster 1, H2bh
HIST1H4D histone cluster 1, H4d
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IER2 immediate early response 2
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IL18 interleukin 18
IRF1 interferon regulatory factor 1
ISG15 ISG15 ubiquitin-like modifier
IVNS1ABP influenza virus NS1A binding protein
JUN jun proto-oncogene
KLF4 Kruppel-like factor 4 (gut)
KLF5 Kruppel-like factor 5 (intestinal)
KLF6 Kruppel-like factor 6
KLF9 Kruppel-like factor 9
KRT18 keratin 18, type I
LGALS9 lectin, galactoside-binding, soluble, 9
MALAT1 metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
MAT2A methionine adenosyltransferase II, alpha
MFSD4 major facilitator superfamily domain containing 4
MKI67 marker of proliferation Ki-67
MUC13 mucin 13, cell surface associated
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NR4A1 nuclear receptor subfamily 4, group A, member 1
NUPR1 nuclear protein, transcriptional regulator, 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAT ornithine aminotransferase
PCBP2 poly(rC) binding protein 2
PIGR polymeric immunoglobulin receptor
PMP22 peripheral myelin protein 22
PTP4A2 protein tyrosine phosphatase type IVA, member 2
RASD1 RAS, dexamethasone-induced 1
RHOB ras homolog family member B
RSAD2 radical S-adenosyl methionine domain containing 2
RTP4 receptor (chemosensory) transporter protein 4
SELENBP1 selenium binding protein 1
SHISA5 shisa family member 5
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC37A2 solute carrier family 37 (glucose-6-phosphate transporter), member 2
SPTBN1 spectrin, beta, non-erythrocytic 1
SRSF5 serine/arginine-rich splicing factor 5
STAT1 signal transducer and activator of transcription 1, 91kDa
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
SYCN syncollin
TFF3 trefoil factor 3 (intestinal)
TGM3 transglutaminase 3
THBS1 thrombospondin 1
TM4SF20 transmembrane 4 L six family member 20
TOP2A topoisomerase (DNA) II alpha 170kDa
TXNIP thioredoxin interacting protein
UBC ubiquitin C
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
USMG5 up-regulated during skeletal muscle growth 5 homolog (mouse)
VMP1 vacuole membrane protein 1
WBP5 WW domain binding protein 5
WFDC2 WAP four-disulfide core domain 2
XIST X inactive specific transcript (non-protein coding)
ZFAND5 zinc finger, AN1-type domain 5
ZFP36 ZFP36 ring finger protein