urinary system disease Gene Set

Dataset DISEASES Experimental Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A disease of anatomical entity that is located_in kidney, ureter, bladder and urethra. (Human Disease Ontology, DOID_18)
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Genes

114 genes associated with the disease urinary system disease in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
CST3 cystatin C 2.79022
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 2.60162
CST9 cystatin 9 (testatin) 2.46332
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 2.37659
NRXN2 neurexin 2 2.34796
CST4 cystatin S 2.0208
PKD2 polycystic kidney disease 2 (autosomal dominant) 1.75714
LPP LIM domain containing preferred translocation partner in lipoma 1.74529
PLA2R1 phospholipase A2 receptor 1, 180kDa 1.70427
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 1.61356
CST1 cystatin SN 1.57113
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 1.35663
APOL2 apolipoprotein L, 2 1.32252
CST8 cystatin 8 (cystatin-related epididymal specific) 1.30085
SLC14A2 solute carrier family 14 (urea transporter), member 2 1.25088
UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2 1.2206
BCAS3 breast carcinoma amplified sequence 3 1.09588
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 1.09588
NAT8 N-acetyltransferase 8 (GCN5-related, putative) 1.09588
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 1.06123
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 1.02486
AQP1 aquaporin 1 (Colton blood group) 1.00628
DEFA1B defensin, alpha 1B 0.995303
GCKR glucokinase (hexokinase 4) regulator 0.995303
MECOM MDS1 and EVI1 complex locus 0.995303
SPATA5L1 spermatogenesis associated 5-like 1 0.978353
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta 0.971299
VEGFA vascular endothelial growth factor A 0.968307
WDR72 WD repeat domain 72 0.965481
APOL1 apolipoprotein L, 1 0.916033
SHROOM3 shroom family member 3 0.894262
ANXA9 annexin A9 0.894262
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 0.872896
GBAP1 glucosidase, beta, acid pseudogene 1 0.872896
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 0.850113
CLDN14 claudin 14 0.850113
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 0.835734
MTMR3 myotubularin related protein 3 0.817078
RSPO3 R-spondin 3 0.817078
CUBN cubilin (intrinsic factor-cobalamin receptor) 0.817078
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 0.790827
HLA-A major histocompatibility complex, class I, A 0.790827
DACH1 dachshund family transcription factor 1 0.774217
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 0.774217
ATXN2 ataxin 2 0.7623
CEP89 centrosomal protein 89kDa 0.752991
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 0.728541
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 0.728541
PDILT protein disulfide isomerase-like, testis expressed 0.724323
PAX8 paired box 8 0.682635
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.682635
CFH complement factor H 0.682635
TBX2 T-box 2 0.682635
MPDU1 mannose-P-dolichol utilization defect 1 0.670996
UMOD uromodulin 0.670996
MICB MHC class I polypeptide-related sequence B 0.63207
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13 0.63207
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.63207
NOTCH4 notch 4 0.63207
TMEM60 transmembrane protein 60 0.602429
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 0.602429
HORMAD2 HORMA domain containing 2 0.602429
CST2 cystatin SA 0.572184
UNCX UNC homeobox 0.572184
DGKH diacylglycerol kinase, eta 0.561725
HLA-DPB2 major histocompatibility complex, class II, DP beta 2 (pseudogene) 0.561725
GNAS GNAS complex locus 0.5306
SYPL2 synaptophysin-like 2 0.52461
WDR37 WD repeat domain 37 0.52461
STC1 stanniocalcin 1 0.52461
JAG1 jagged 1 0.52461
RNASEH2C ribonuclease H2, subunit C 0.464771
CST5 cystatin D 0.438544
GRIK2 glutamate receptor, ionotropic, kainate 2 0.403461
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 0.368757
RGS14 regulator of G-protein signaling 14 0.368757
GPC5 glypican 5 0.345945
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.327313
ACOXL acyl-CoA oxidase-like 0.327313
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35 0.311576
PDZRN3 PDZ domain containing ring finger 3 0.297866
SASH1 SAM and SH3 domain containing 1 0.285417
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.285417
EPHA7 EPH receptor A7 0.256228
COX18 COX18 cytochrome c oxidase assembly factor 0.256228
CHAF1B chromatin assembly factor 1, subunit B (p60) 0.256228
GLT1D1 glycosyltransferase 1 domain containing 1 0.256228
RPS12 ribosomal protein S12 0.197766
GAS2 growth arrest-specific 2 0.197766
UBE2E2 ubiquitin-conjugating enzyme E2E 2 0.197766
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa 0.197766
COL8A1 collagen, type VIII, alpha 1 0.197766
TMEM171 transmembrane protein 171 0.197766
TET3 tet methylcytosine dioxygenase 3 0.15771
TIAM1 T-cell lymphoma invasion and metastasis 1 0.15771
GPATCH2 G patch domain containing 2 0.126165
TJP2 tight junction protein 2 0.126165
LIMK2 LIM domain kinase 2 0.126165
PTPRM protein tyrosine phosphatase, receptor type, M 0.126165
PCSK2 proprotein convertase subtilisin/kexin type 2 0.100789
CNKSR3 CNKSR family member 3 0.100789
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 0.100789
GPC6 glypican 6 0.080593
SVIP small VCP/p97-interacting protein 0.080593
AUH AU RNA binding protein/enoyl-CoA hydratase 0.080593
TMEM244 transmembrane protein 244 0.080593
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 0.064973
NRG1 neuregulin 1 0.064973
ARHGAP20 Rho GTPase activating protein 20 0.052255
RIN3 Ras and Rab interactor 3 0.052255
ELMO1 engulfment and cell motility 1 0.052255
SH3BP4 SH3-domain binding protein 4 0.043246
NR5A2 nuclear receptor subfamily 5, group A, member 2 0.043246
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 0.043246