urinary system cancer Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
Description An organ system cancer that is located_in the kidneys, ureteres, bladder or urethra. (Human Disease Ontology, DOID_3996)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:3996
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Genes

119 genes associated with the disease urinary system cancer in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
TACC3 transforming, acidic coiled-coil containing protein 3 1.49399
DLG2 discs, large homolog 2 (Drosophila) 0.863589
TCN2 transcobalamin II 0.483661
PSCA prostate stem cell antigen 0.474348
CLPTM1L CLPTM1-like 0.474348
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) 0.470993
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.457406
EPAS1 endothelial PAS domain protein 1 0.452405
MYNN myoneurin 0.444689
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.443018
ZEB2 zinc finger E-box binding homeobox 2 0.432325
SCARB1 scavenger receptor class B, member 1 0.428796
LSP1 lymphocyte-specific protein 1 0.426309
PCSK9 proprotein convertase subtilisin/kexin type 9 0.41791
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10 0.41791
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 0.396759
PDZD2 PDZ domain containing 2 0.394976
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 0.392011
MEOX2 mesenchyme homeobox 2 0.387579
MCF2L MCF.2 cell line derived transforming sequence-like 0.376937
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 0.37647
CEP85L centrosomal protein 85kDa-like 0.369654
ENPEP glutamyl aminopeptidase (aminopeptidase A) 0.367469
USP10 ubiquitin specific peptidase 10 0.366972
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 0.366972
TMEM44 transmembrane protein 44 0.365935
KAT2B K(lysine) acetyltransferase 2B 0.364717
CCDC3 coiled-coil domain containing 3 0.363142
LINC00189 long intergenic non-protein coding RNA 189 0.362774
DCC DCC netrin 1 receptor 0.361067
COL13A1 collagen, type XIII, alpha 1 0.359866
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 0.359837
LRRC31 leucine rich repeat containing 31 0.359545
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 0.358706
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.358174
OGFRL1 opioid growth factor receptor-like 1 0.35624
FRMD8 FERM domain containing 8 0.355986
ABLIM1 actin binding LIM protein 1 0.355613
ASCC2 activating signal cointegrator 1 complex subunit 2 0.353873
PCSK6 proprotein convertase subtilisin/kexin type 6 0.353124
IQSEC3 IQ motif and Sec7 domain 3 0.351351
MAN1B1 mannosidase, alpha, class 1B, member 1 0.348867
SHROOM3 shroom family member 3 0.348477
LOC146513 uncharacterized LOC146513 0.348477
MIR99AHG mir-99a-let-7c cluster host gene 0.3484
SNAP47 synaptosomal-associated protein, 47kDa 0.348172
CNTN4 contactin 4 0.347947
LOC100507462 uncharacterized LOC100507462 0.3478
ZMYND15 zinc finger, MYND-type containing 15 0.34758
TTYH1 tweety family member 1 0.345997
LOC100507195 uncharacterized LOC100507195 0.345738
BIN2 bridging integrator 2 0.345674
RGS6 regulator of G-protein signaling 6 0.345047
BTNL2 butyrophilin-like 2 0.343698
CELA1 chymotrypsin-like elastase family, member 1 0.343311
ALKBH6 alkB, alkylation repair homolog 6 (E. coli) 0.342564
DOCK1 dedicator of cytokinesis 1 0.341719
FUT2 fucosyltransferase 2 (secretor status included) 0.341316
KIRREL3 kin of IRRE like 3 (Drosophila) 0.341316
CLIP3 CAP-GLY domain containing linker protein 3 0.340701
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 0.340213
FAM129A family with sequence similarity 129, member A 0.337914
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 0.337091
SORBS2 sorbin and SH3 domain containing 2 0.336737
PTPRO protein tyrosine phosphatase, receptor type, O 0.336606
PAQR5 progestin and adipoQ receptor family member V 0.33652
GPA33 glycoprotein A33 (transmembrane) 0.336477
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional) 0.335883
AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2 0.335431
SP100 SP100 nuclear antigen 0.33519
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6 0.334912
ROR1 receptor tyrosine kinase-like orphan receptor 1 0.334255
GTSF1 gametocyte specific factor 1 0.333992
RNF168 ring finger protein 168, E3 ubiquitin protein ligase 0.333733
FAM13A family with sequence similarity 13, member A 0.333333
DPH6 diphthamine biosynthesis 6 0.333119
EML2 echinoderm microtubule associated protein like 2 0.332053
FOXP1 forkhead box P1 0.332053
MRPL23 mitochondrial ribosomal protein L23 0.332053
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 0.331272
PPA2 pyrophosphatase (inorganic) 2 0.329432
GRM5 glutamate receptor, metabotropic 5 0.327036
PARK2 parkin RBR E3 ubiquitin protein ligase 0.326863
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 0.326814
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 0.326692
PITPNM3 PITPNM family member 3 0.326619
DOCK5 dedicator of cytokinesis 5 0.326284
CDH23 cadherin-related 23 0.325978
DGKI diacylglycerol kinase, iota 0.32545
TMEM222 transmembrane protein 222 0.325359
CEP128 centrosomal protein 128kDa 0.324948
GSG1 germ cell associated 1 0.32482
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila) 0.324043
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 0.323945
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 0.323678
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.323582
AADACL3 arylacetamide deacetylase-like 3 0.323486
ARID1A AT rich interactive domain 1A (SWI-like) 0.322599
INSC inscuteable homolog (Drosophila) 0.322327
GALNT18 polypeptide N-acetylgalactosaminyltransferase 18 0.322214
LOXHD1 lipoxygenase homology domains 1 0.321948
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase 0.321904
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.321619
SLIT3 slit homolog 3 (Drosophila) 0.321468
MROH2A maestro heat-like repeat family member 2A 0.321382
RAI1 retinoic acid induced 1 0.321297
MTUS1 microtubule associated tumor suppressor 1 0.320958
ADGRB3 adhesion G protein-coupled receptor B3 0.320937
SASH1 SAM and SH3 domain containing 1 0.320502
ONECUT2 one cut homeobox 2 0.320339
GPR17 G protein-coupled receptor 17 0.320318
CACNB4 calcium channel, voltage-dependent, beta 4 subunit 0.318388
LARGE like-glycosyltransferase 0.317144
CASC15 cancer susceptibility candidate 15 (non-protein coding) 0.312705
AXIN2 axin 2 0.310152
ZC3HC1 zinc finger, C3HC-type containing 1 0.305338
DNAH12 dynein, axonemal, heavy chain 12 0.287504
IZUMO1 izumo sperm-egg fusion 1 0.285037
TMEM132D transmembrane protein 132D 0.271489