ulcerative colitis Gene Set

Dataset DISEASES Experimental Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A colitis that is predominantly confined to the mucosa located_in colon and includes characteristic ulcers, or open sores. (Human Disease Ontology, DOID_8577)
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Genes

111 genes associated with the disease ulcerative colitis in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
CARD9 caspase recruitment domain family, member 9 1.31515
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 1.2894
APEH acylaminoacyl-peptide hydrolase 1.22898
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.18942
ATF6B activating transcription factor 6 beta 1.17894
TNXB tenascin XB 1.17894
IFNG interferon, gamma 1.17894
C11ORF30 chromosome 11 open reading frame 30 1.11998
GNA12 guanine nucleotide binding protein (G protein) alpha 12 1.06123
AMZ1 archaelysin family metallopeptidase 1 1.06123
PUS10 pseudouridylate synthase 10 1.00628
NXPE1 neurexophilin and PC-esterase domain family, member 1 0.982645
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.872896
IL1R1 interleukin 1 receptor, type I 0.85991
PTOV1 prostate tumor overexpressed 1 0.850113
DAP death-associated protein 0.835734
SORCS2 sortilin-related VPS10 domain containing receptor 2 0.817078
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.817078
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 0.817078
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta 0.817078
RNF186 ring finger protein 186 0.790827
ZPBP2 zona pellucida binding protein 2 0.752991
ICOSLG inducible T-cell co-stimulator ligand 0.745324
GPR35 G protein-coupled receptor 35 0.73332
KPNA7 karyopherin alpha 7 (importin alpha 8) 0.728541
LSP1 lymphocyte-specific protein 1 0.724323
CXCR2 chemokine (C-X-C motif) receptor 2 0.724323
VEGFA vascular endothelial growth factor A 0.69843
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 0.69843
SLMAP sarcolemma associated protein 0.670996
CRADD CASP2 and RIPK1 domain containing adaptor with death domain 0.661797
NRG3 neuregulin 3 0.63207
CEP72 centrosomal protein 72kDa 0.63207
TRAM2 translocation associated membrane protein 2 0.63207
NUP153 nucleoporin 153kDa 0.602429
FAM213B family with sequence similarity 213, member B 0.58494
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.58494
CCL25 chemokine (C-C motif) ligand 25 0.58494
MST1 macrophage stimulating 1 0.572184
PARK7 parkinson protein 7 0.561725
FBLN2 fibulin 2 0.552621
BSN bassoon presynaptic cytomatrix protein 0.544585
NXN nucleoredoxin 0.544585
OTUD3 OTU deubiquitinase 3 0.544585
TUBGCP4 tubulin, gamma complex associated protein 4 0.537125
TSPAN18 tetraspanin 18 0.5306
NKX2-3 NK2 homeobox 3 0.52461
PRDM1 PR domain containing 1, with ZNF domain 0.52461
IL10 interleukin 10 0.52461
IL23R interleukin 23 receptor 0.52461
AK5 adenylate kinase 5 0.52461
IRF5 interferon regulatory factor 5 0.486425
GSDMB gasdermin B 0.464771
ZFP90 ZFP90 zinc finger protein 0.464771
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.449873
IL7R interleukin 7 receptor 0.449873
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D 0.449873
FBXO9 F-box protein 9 0.414708
WNT4 wingless-type MMTV integration site family, member 4 0.403461
SLC26A3 solute carrier family 26 (anion exchanger), member 3 0.403461
KIF21B kinesin family member 21B 0.368757
IL26 interleukin 26 0.368757
ZNF767P zinc finger family member 767, pseudogene 0.368757
IL17REL interleukin 17 receptor E-like 0.368757
NUPL2 nucleoporin like 2 0.368757
MRGPRX4 MAS-related GPR, member X4 0.368757
HMHB1 histocompatibility (minor) HB-1 0.345945
CUL2 cullin 2 0.327313
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.327313
AQP12B aquaporin 12B 0.297866
CAMK1G calcium/calmodulin-dependent protein kinase IG 0.285417
C2CD3 C2 calcium-dependent domain containing 3 0.285417
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.274608
ADAD1 adenosine deaminase domain containing 1 (testis-specific) 0.264872
PRRT1 proline-rich transmembrane protein 1 0.264872
C1ORF106 chromosome 1 open reading frame 106 0.256228
INSL4 insulin-like 4 (placenta) 0.256228
RAB32 RAB32, member RAS oncogene family 0.256228
JAK2 Janus kinase 2 0.256228
DLD dihydrolipoamide dehydrogenase 0.256228
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 0.256228
FAM19A1 family with sequence similarity 19 (chemokine (C-C motif)-like), member A1 0.256228
TSKU tsukushi, small leucine rich proteoglycan 0.197766
TMEM170A transmembrane protein 170A 0.197766
HLA-A major histocompatibility complex, class I, A 0.197766
HDAC9 histone deacetylase 9 0.197766
CIITA class II, major histocompatibility complex, transactivator 0.15771
MYH13 myosin, heavy chain 13, skeletal muscle 0.15771
RBM26 RNA binding motif protein 26 0.15771
RSPO2 R-spondin 2 0.15771
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 0.15771
GJB2 gap junction protein, beta 2, 26kDa 0.15771
BPIFB4 BPI fold containing family B, member 4 0.126165
MKX mohawk homeobox 0.126165
CCNY cyclin Y 0.126165
ZP2 zona pellucida glycoprotein 2 (sperm receptor) 0.100789
SATB2 SATB homeobox 2 0.100789
CD28 CD28 molecule 0.080593
HLA-DOB major histocompatibility complex, class II, DO beta 0.080593
IL19 interleukin 19 0.080593
SH3BP4 SH3-domain binding protein 4 0.064973
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa 0.064973
MUSK muscle, skeletal, receptor tyrosine kinase 0.064973
LAMB1 laminin, beta 1 0.064973
FBXL17 F-box and leucine-rich repeat protein 17 0.064973
ADCK3 aarF domain containing kinase 3 0.064973
CDH13 cadherin 13 0.052255
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 0.052255
GPC5 glypican 5 0.052255
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 0.052255
BMPER BMP binding endothelial regulator 0.043246