ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the multivesicular body (MVB) sorting pathway; ubiquitin-tagged proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation. (Gene Ontology, GO_0043162)
External Link http://amigo.geneontology.org/amigo/term/GO:0043162
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Genes

16 genes participating in the ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
HDAC6 histone deacetylase 6
MVB12A multivesicular body subunit 12A
MVB12B multivesicular body subunit 12B
NDFIP1 Nedd4 family interacting protein 1
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
PTPN23 protein tyrosine phosphatase, non-receptor type 23
RNF115 ring finger protein 115
RNF126 ring finger protein 126
TOM1L1 target of myb1 (chicken)-like 1
TSG101 tumor susceptibility 101
UBAP1 ubiquitin associated protein 1
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)
VPS37A vacuolar protein sorting 37 homolog A (S. cerevisiae)
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae)
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae)