ubiquitin ligase complex Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex that includes a ubiquitin-protein ligase and other proteins that may confer substrate specificity on the complex. (Gene Ontology, GO_0000151)
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Genes

173 proteins localized to the ubiquitin ligase complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
RBX1 ring-box 1, E3 ubiquitin protein ligase 0.663342
CUL2 cullin 2 0.663342
CUL1 cullin 1 0.663342
CUL7 cullin 7 0.663342
RNF31 ring finger protein 31 0.663342
CAND1 cullin-associated and neddylation-dissociated 1 0.663342
CUL5 cullin 5 0.663342
FBXL15 F-box and leucine-rich repeat protein 15 0.663342
CUL9 cullin 9 0.663342
ANAPC13 anaphase promoting complex subunit 13 0.663342
UBE2B ubiquitin-conjugating enzyme E2B 0.663342
RNF8 ring finger protein 8, E3 ubiquitin protein ligase 0.663342
RNF7 ring finger protein 7 0.663342
RNF2 ring finger protein 2 0.663342
BRCA1 breast cancer 1, early onset 0.663342
CUL3 cullin 3 0.663342
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 0.663342
TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase 0.663342
DCAF13 DDB1 and CUL4 associated factor 13 0.663342
DCAF12 DDB1 and CUL4 associated factor 12 0.663342
DCAF11 DDB1 and CUL4 associated factor 11 0.663342
DCAF10 DDB1 and CUL4 associated factor 10 0.663342
DCAF17 DDB1 and CUL4 associated factor 17 0.663342
DCAF16 DDB1 and CUL4 associated factor 16 0.663342
KLHL25 kelch-like family member 25 0.663342
KLHL21 kelch-like family member 21 0.663342
KLHL20 kelch-like family member 20 0.663342
KLHL22 kelch-like family member 22 0.663342
CDC23 cell division cycle 23 0.663342
BRAP BRCA1 associated protein 0.663342
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 0.663342
RNF40 ring finger protein 40, E3 ubiquitin protein ligase 0.663342
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.663342
FBXO44 F-box protein 44 0.663342
PARK2 parkin RBR E3 ubiquitin protein ligase 0.663342
LMO7 LIM domain 7 0.663342
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase 0.663342
RNF168 ring finger protein 168, E3 ubiquitin protein ligase 0.663342
GAN gigaxonin 0.663342
CRBN cereblon 0.663342
DDB1 damage-specific DNA binding protein 1, 127kDa 0.663342
SPOPL speckle-type POZ protein-like 0.663342
BRE brain and reproductive organ-expressed (TNFRSF1A modulator) 0.663342
FBXL7 F-box and leucine-rich repeat protein 7 0.663342
KEAP1 kelch-like ECH-associated protein 1 0.663342
CUL4A cullin 4A 0.663342
CUL4B cullin 4B 0.663342
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) 0.663342
RNF11 ring finger protein 11 0.663342
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1 0.663342
FBXO9 F-box protein 9 0.663342
FBXO8 F-box protein 8 0.663342
FBXW8 F-box and WD repeat domain containing 8 0.663342
FBXW4 F-box and WD repeat domain containing 4 0.663342
FBXW5 F-box and WD repeat domain containing 5 0.663342
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 0.663342
BRCC3 BRCA1/BRCA2-containing complex, subunit 3 0.663342
UBE2N ubiquitin-conjugating enzyme E2N 0.663342
UBE2A ubiquitin-conjugating enzyme E2A 0.663342
UBE2C ubiquitin-conjugating enzyme E2C 0.663342
UBE2S ubiquitin-conjugating enzyme E2S 0.663342
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) 0.663342
CDC16 cell division cycle 16 0.663342
FBXO4 F-box protein 4 0.663342
FBXO6 F-box protein 6 0.663342
FBXO7 F-box protein 7 0.663342
ZER1 zyg-11 related, cell cycle regulator 0.663342
FBXL19 F-box and leucine-rich repeat protein 19 0.663342
SHARPIN SHANK-associated RH domain interactor 0.663342
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein 0.663342
ENC1 ectodermal-neural cortex 1 (with BTB domain) 0.663342
USP47 ubiquitin specific peptidase 47 0.663342
ASB4 ankyrin repeat and SOCS box containing 4 0.663342
ERCC8 excision repair cross-complementation group 8 0.663342
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 0.663342
DCAF7 DDB1 and CUL4 associated factor 7 0.663342
DCAF6 DDB1 and CUL4 associated factor 6 0.663342
DCAF5 DDB1 and CUL4 associated factor 5 0.663342
DCAF4 DDB1 and CUL4 associated factor 4 0.663342
DCAF8 DDB1 and CUL4 associated factor 8 0.663342
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 0.663342
KLHL42 kelch-like family member 42 0.663342
WWP1 WW domain containing E3 ubiquitin protein ligase 1 0.663342
COMMD1 copper metabolism (Murr1) domain containing 1 0.663342
FBXO10 F-box protein 10 0.663342
FBXO11 F-box protein 11 0.663342
FBXO17 F-box protein 17 0.663342
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 0.663342
TSPAN17 tetraspanin 17 0.663342
KLHL12 kelch-like family member 12 0.663342
KLHL13 kelch-like family member 13 0.663342
KCTD13 potassium channel tetramerization domain containing 13 0.663342
ANAPC1 anaphase promoting complex subunit 1 0.663342
ANAPC2 anaphase promoting complex subunit 2 0.663342
ANAPC5 anaphase promoting complex subunit 5 0.663342
ANAPC4 anaphase promoting complex subunit 4 0.663342
ANAPC7 anaphase promoting complex subunit 7 0.663342
UBE4B ubiquitination factor E4B 0.663342
KLHL41 kelch-like family member 41 0.663342
SPOP speckle-type POZ protein 0.663342
FBXL5 F-box and leucine-rich repeat protein 5 0.663342
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 0.663342
TMEM189 transmembrane protein 189 0.663342
UBE2E1 ubiquitin-conjugating enzyme E2E 1 0.663342
TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) 0.663342
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 0.663342
SKP1 S-phase kinase-associated protein 1 0.663342
USP33 ubiquitin specific peptidase 33 0.663342
RNF20 ring finger protein 20, E3 ubiquitin protein ligase 0.663342
BMI1 BMI1 proto-oncogene, polycomb ring finger 0.663342
CCNF cyclin F 0.663342
FBXW11 F-box and WD repeat domain containing 11 0.663342
BARD1 BRCA1 associated RING domain 1 0.663342
CDC27 cell division cycle 27 0.663342
FBXL3 F-box and leucine-rich repeat protein 3 0.663342
FBXO31 F-box protein 31 0.663342
FBXO21 F-box protein 21 0.663342
KLHL7 kelch-like family member 7 0.663342
ANAPC10 anaphase promoting complex subunit 10 0.663342
KLHL3 kelch-like family member 3 0.663342
KLHL8 kelch-like family member 8 0.663342
KLHL9 kelch-like family member 9 0.663342
ANAPC11 anaphase promoting complex subunit 11 0.663342
ANAPC16 anaphase promoting complex subunit 16 0.663342
UBE2L3 ubiquitin-conjugating enzyme E2L 3 0.663342
ANAPC15 anaphase promoting complex subunit 15 0.663342
FBXO24 F-box protein 24 0.663342
FBXO25 F-box protein 25 0.663342
TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough 0.663342
FBXO27 F-box protein 27 0.663342
CDC26 cell division cycle 26 0.663342
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) 0.237908
SUGT1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) 0.237908
ATG3 autophagy related 3 0.237908
FBXO2 F-box protein 2 0.237908
GLMN glomulin, FKBP associated protein 0.237908
UBE4A ubiquitination factor E4A 0.237908
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 0.237908
UBE2D1 ubiquitin-conjugating enzyme E2D 1 0.237908
UBE2D2 ubiquitin-conjugating enzyme E2D 2 0.237908
DDB2 damage-specific DNA binding protein 2, 48kDa 0.237908
KLHL2 kelch-like family member 2 0.237908
WWP2 WW domain containing E3 ubiquitin protein ligase 2 0.237908
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase 0.237908
KCTD10 potassium channel tetramerization domain containing 10 0.237908
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase 0.237908
FBXL4 F-box and leucine-rich repeat protein 4 0.237908
VCP valosin containing protein 0.237908
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 0.237908
DERL1 derlin 1 0.237908
RNF144B ring finger protein 144B 0.237908
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 0.098109
TRAF2 TNF receptor-associated factor 2 0.098109
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.098109
NEURL2 neuralized E3 ubiquitin protein ligase 2 0.03318
OTULIN OTU deubiquitinase with linear linkage specificity 0.03318
ASB2 ankyrin repeat and SOCS box containing 2 0.03318
FBXO15 F-box protein 15 0.03318
FBXL12 F-box and leucine-rich repeat protein 12 0.03318
CACUL1 CDK2-associated, cullin domain 1 0.03318
MIB2 mindbomb E3 ubiquitin protein ligase 2 0.03318
UBR1 ubiquitin protein ligase E3 component n-recognin 1 0.03318
UBR2 ubiquitin protein ligase E3 component n-recognin 2 0.03318
PCGF6 polycomb group ring finger 6 0.00547
PCGF2 polycomb group ring finger 2 0.00547
CBX8 chromobox homolog 8 0.00547
PHC2 polyhomeotic homolog 2 (Drosophila) 0.00547
CBX4 chromobox homolog 4 0.00547
CBX2 chromobox homolog 2 0.00547
PHC3 polyhomeotic homolog 3 (Drosophila) 0.00547
PHC1 polyhomeotic homolog 1 (Drosophila) 0.00547
RING1 ring finger protein 1 0.00547
CBX7 chromobox homolog 7 0.004756