typhoid fever Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A primary bacterial infectious disease that is a communicable systemic illness, has_material_basis_in Salmonella enterica subsp enterica serovar Typhi, which is transmitted_by ingestion of food or water contaminated with the feces of an infected person. The infection has_symptom fever, has_symptom diarrhea, has_symptom prostration, has_symptom headache, has_symptom splenomegaly, has_symptom liver enlargement, has_symptom eruption of rose-colored spots, and has_symptom leukopenia. (Human Disease Ontology, DOID_13258)
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Genes

9 genes associated with the disease typhoid fever in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
LTA lymphotoxin alpha
TLR4 toll-like receptor 4
TNF tumor necrosis factor