typhoid fever Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A primary bacterial infectious disease that is a communicable systemic illness, has_material_basis_in Salmonella enterica subsp enterica serovar Typhi, which is transmitted_by ingestion of food or water contaminated with the feces of an infected person. The infection has_symptom fever, has_symptom diarrhea, has_symptom prostration, has_symptom headache, has_symptom splenomegaly, has_symptom liver enlargement, has_symptom eruption of rose-colored spots, and has_symptom leukopenia. (Human Disease Ontology, DOID_13258)
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Genes

142 genes co-occuring with the disease typhoid fever in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
GALE UDP-galactose-4-epimerase 1.68498
HIST1H1D histone cluster 1, H1d 1.67277
CD79A CD79a molecule, immunoglobulin-associated alpha 1.58626
HTRA1 HtrA serine peptidase 1 1.43332
STX12 syntaxin 12 1.37687
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) 1.1635
TLR5 toll-like receptor 5 1.12193
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 1.07656
GHITM growth hormone inducible transmembrane protein 1.0648
HDAC11 histone deacetylase 11 0.962472
SUMF2 sulfatase modifying factor 2 0.954108
DPT dermatopontin 0.94078
LTB lymphotoxin beta (TNF superfamily, member 3) 0.939949
SIVA1 SIVA1, apoptosis-inducing factor 0.926279
CFP complement factor properdin 0.921736
CD4 CD4 molecule 0.913903
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 0.912668
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26 0.861409
KLHL12 kelch-like family member 12 0.860999
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial 0.849536
OR13F1 olfactory receptor, family 13, subfamily F, member 1 0.847488
HLA-E major histocompatibility complex, class I, E 0.833968
ADA adenosine deaminase 0.796232
G6PD glucose-6-phosphate dehydrogenase 0.793361
RAB29 RAB29, member RAS oncogene family 0.772479
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase 0.770844
RAB32 RAB32, member RAS oncogene family 0.703938
IL6 interleukin 6 0.698715
MCFD2 multiple coagulation factor deficiency 2 0.685491
ODF1 outer dense fiber of sperm tails 1 0.673917
SALL1 spalt-like transcription factor 1 0.661594
POMC proopiomelanocortin 0.648533
ALPPL2 alkaline phosphatase, placental-like 2 0.640251
ALPP alkaline phosphatase, placental 0.639857
ALPL alkaline phosphatase, liver/bone/kidney 0.63907
TNF tumor necrosis factor 0.637495
HP haptoglobin 0.626103
HPR haptoglobin-related protein 0.619834
TLR4 toll-like receptor 4 0.616312
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4 0.605762
SAT1 spermidine/spermine N1-acetyltransferase 1 0.604981
ALB albumin 0.571107
LYZ lysozyme 0.557509
TES testin LIM domain protein 0.550911
DEFA3 defensin, alpha 3, neutrophil-specific 0.542767
PSD pleckstrin and Sec7 domain containing 0.535409
SLC7A4 solute carrier family 7, member 4 0.533088
S100A9 S100 calcium binding protein A9 0.531928
THAP3 THAP domain containing, apoptosis associated protein 3 0.530768
C11ORF40 chromosome 11 open reading frame 40 0.522659
KLKB1 kallikrein B, plasma (Fletcher factor) 1 0.516494
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.510344
PACRG PARK2 co-regulated 0.502675
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.483224
HIST1H1A histone cluster 1, H1a 0.478668
WASH7P WAS protein family homolog 7 pseudogene 0.478668
WASH1 WAS protein family homolog 1 0.474877
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 0.474498
WASH6P WAS protein family homolog 6 pseudogene 0.472604
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 0.457487
BATF2 basic leucine zipper transcription factor, ATF-like 2 0.457487
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.457109
TUBGCP4 tubulin, gamma complex associated protein 4 0.450324
NONO non-POU domain containing, octamer-binding 0.439034
TENM1 teneurin transmembrane protein 1 0.437906
CRP C-reactive protein, pentraxin-related 0.435651
ANGPTL6 angiopoietin-like 6 0.43227
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.431519
USP18 ubiquitin specific peptidase 18 0.42214
PHB prohibitin 0.42214
NCF2 neutrophil cytosolic factor 2 0.42139
IL1B interleukin 1, beta 0.418768
TAS1R1 taste receptor, type 1, member 1 0.412779
A1BG alpha-1-B glycoprotein 0.412031
AFF2 AF4/FMR2 family, member 2 0.404931
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 0.400453
F12 coagulation factor XII (Hageman factor) 0.398589
LAD1 ladinin 1 0.387423
KNG1 kininogen 1 0.379626
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 0.373698
HLA-B major histocompatibility complex, class I, B 0.361502
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 0.357077
DNM1 dynamin 1 0.350452
NLRC4 NLR family, CARD domain containing 4 0.346042
LITAF lipopolysaccharide-induced TNF factor 0.326646
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.324458
UST uronyl-2-sulfotransferase 0.322637
TADA1 transcriptional adaptor 1 0.318999
PRKCA protein kinase C, alpha 0.318635
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 0.315729
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 0.309566
HOPX HOP homeobox 0.309204
ACAP3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 0.303059
TAPBP TAP binding protein (tapasin) 0.298371
DLD dihydrolipoamide dehydrogenase 0.289744
TMPO thymopoietin 0.287952
CAT catalase 0.285802
DUT deoxyuridine triphosphatase 0.284013
SEPT2 septin 2 0.279367
FYN FYN proto-oncogene, Src family tyrosine kinase 0.279011
F2 coagulation factor II (thrombin) 0.275801
SELL selectin L 0.271886
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 0.268687
IL1RL1 interleukin 1 receptor-like 1 0.26266
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.261599
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide 0.258417
MICA MHC class I polypeptide-related sequence A 0.255241
PFKM phosphofructokinase, muscle 0.254183
CPSF3L cleavage and polyadenylation specific factor 3-like 0.237009
BCO1 beta-carotene oxygenase 1 0.237009
OR6B2 olfactory receptor, family 6, subfamily B, member 2 0.232489
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.228679
YME1L1 YME1-like 1 ATPase 0.22454
GRHL1 grainyhead-like 1 (Drosophila) 0.223853
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 0.223165
HHAT hedgehog acyltransferase 0.222822
CYGB cytoglobin 0.222479
KLK8 kallikrein-related peptidase 8 0.218374
FBLIM1 filamin binding LIM protein 1 0.217352
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 0.217012
CD27 CD27 molecule 0.216332
STAB2 stabilin 2 0.215992
CSN1S1 casein alpha s1 0.215653
LRP5 low density lipoprotein receptor-related protein 5 0.214975
ITLN1 intelectin 1 (galactofuranose binding) 0.210589
ZNF77 zinc finger protein 77 0.209248
ARPP21 cAMP-regulated phosphoprotein, 21kDa 0.206248
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.202946
ANXA4 annexin A4 0.201635
LST1 leukocyte specific transcript 1 0.196779
FLCN folliculin 0.192657
CLEC3B C-type lectin domain family 3, member B 0.191097
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 0.182666
IL12B interleukin 12B 0.17952
FPR1 formyl peptide receptor 1 0.173571
LHCGR luteinizing hormone/choriogonadotropin receptor 0.172544
TFF2 trefoil factor 2 0.169812
APOA4 apolipoprotein A-IV 0.168854
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 0.163938
FICD FIC domain containing 0.163523
CCR7 chemokine (C-C motif) receptor 7 0.161716
CD59 CD59 molecule, complement regulatory protein 0.158778