type ii diabetes mellitus Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
Description A diabetes mellitus that involves high blood glucose resulting from cells fail to use insulin properly. (Human Disease Ontology, DOID_9352)
External Link http://compbio.charite.de/hpoweb/showterm?id=HP:0005978
Similar Terms
Downloads & Tools

Genes

112 genes associated with the type ii diabetes mellitus phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALAS2 5'-aminolevulinate synthase 2
ALMS1 Alstrom syndrome protein 1
AR androgen receptor
ARL2BP ADP-ribosylation factor-like 2 binding protein
ARL6 ADP-ribosylation factor-like 6
ATM ATM serine/threonine kinase
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BEST1 bestrophin 1
BLM Bloom syndrome, RecQ helicase-like
C2ORF71 chromosome 2 open reading frame 71
C8ORF37 chromosome 8 open reading frame 37
CA4 carbonic anhydrase IV
CDHR1 cadherin-related family member 1
CERKL ceramide kinase-like
CLIP2 CAP-GLY domain containing linker protein 2
CLRN1 clarin 1
CNGA1 cyclic nucleotide gated channel alpha 1
CNGB1 cyclic nucleotide gated channel beta 1
COX1
COX2
COX3
CRB1 crumbs family member 1, photoreceptor morphogenesis associated
CRX cone-rod homeobox
DHDDS dehydrodolichyl diphosphate synthase
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
ELN elastin
EYS eyes shut homolog (Drosophila)
FAM161A family with sequence similarity 161, member A
FBN1 fibrillin 1
FSCN2 fascin actin-bundling protein 2, retinal
GCK glucokinase (hexokinase 4)
GTF2I general transcription factor IIi
GTF2IRD1 GTF2I repeat domain containing 1
GUCA1B guanylate cyclase activator 1B (retina)
HMGA1 high mobility group AT-hook 1
HNF1A HNF1 homeobox A
HNF1B HNF1 homeobox B
HNF4A hepatocyte nuclear factor 4, alpha
IDH3B isocitrate dehydrogenase 3 (NAD+) beta
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
IMPG2 interphotoreceptor matrix proteoglycan 2
INSR insulin receptor
KIZ kizuna centrosomal protein
KLF11 Kruppel-like factor 11
KLHL7 kelch-like family member 7
LIG4 ligase IV, DNA, ATP-dependent
LIMK1 LIM domain kinase 1
LRAT lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
MAK male germ cell-associated kinase
MERTK MER proto-oncogene, tyrosine kinase
MT-ND4 NADH dehydrogenase, subunit 4 (complex I)
MT-ND5 NADH dehydrogenase, subunit 5 (complex I)
MT-ND6 NADH dehydrogenase, subunit 6 (complex I)
MT-TF tRNA
MT-TH tRNA
MT-TL1 tRNA
MT-TQ tRNA
MT-TS1 tRNA
MT-TS2 tRNA
MT-TW tRNA
ND1
NDN necdin, melanoma antigen (MAGE) family member
NEK2 NIMA-related kinase 2
NR2E3 nuclear receptor subfamily 2, group E, member 3
NRL neural retina leucine zipper
OFD1 oral-facial-digital syndrome 1
PAX4 paired box 4
PCNT pericentrin
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma
PDX1 pancreatic and duodenal homeobox 1
PLCD1 phospholipase C, delta 1
PRCD progressive rod-cone degeneration
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PROM1 prominin 1
PRPF3 pre-mRNA processing factor 3
PRPF31 pre-mRNA processing factor 31
PRPF4 pre-mRNA processing factor 4
PRPF6 pre-mRNA processing factor 6
PRPF8 pre-mRNA processing factor 8
PRPH2 peripherin 2 (retinal degeneration, slow)
PTF1A pancreas specific transcription factor, 1a
RBP3 retinol binding protein 3, interstitial
RDH12 retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
RFC2 replication factor C (activator 1) 2, 40kDa
RGR retinal G protein coupled receptor
RHO rhodopsin
RLBP1 retinaldehyde binding protein 1
ROM1 retinal outer segment membrane protein 1
RP1 retinitis pigmentosa 1 (autosomal dominant)
RP2 retinitis pigmentosa 2 (X-linked recessive)
RP9 retinitis pigmentosa 9 (autosomal dominant)
RPE65 retinal pigment epithelium-specific protein 65kDa
RPGR retinitis pigmentosa GTPase regulator
SAG S-antigen; retina and pineal gland (arrestin)
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SLC7A14 solute carrier family 7, member 14
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SNRPN small nuclear ribonucleoprotein polypeptide N
SPATA7 spermatogenesis associated 7
SPINK1 serine peptidase inhibitor, Kazal type 1
TBL2 transducin (beta)-like 2
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TTC8 tetratricopeptide repeat domain 8
TUB tubby bipartite transcription factor
TULP1 tubby like protein 1
USH2A Usher syndrome 2A (autosomal recessive, mild)
ZNF513 zinc finger protein 513