type 2 diabetes mellitus Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A diabetes mellitus that involves high blood glucose resulting from cells fail to use insulin properly. (Human Disease Ontology, DOID_9352)
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Genes

510 genes co-occuring with the disease type 2 diabetes mellitus in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
INS insulin 3.87739
DPP4 dipeptidyl-peptidase 4 2.44809
GCG glucagon 2.38609
INSR insulin receptor 2.1655
IAPP islet amyloid polypeptide 2.12616
ALB albumin 2.02839
PPARG peroxisome proliferator-activated receptor gamma 1.99872
LEP leptin 1.99826
GLP1R glucagon-like peptide 1 receptor 1.88344
IRS1 insulin receptor substrate 1 1.8409
APOB apolipoprotein B 1.83047
CRP C-reactive protein, pentraxin-related 1.82549
GCK glucokinase (hexokinase 4) 1.82413
GIP gastric inhibitory polypeptide 1.816
ACE angiotensin I converting enzyme 1.79661
ADRB3 adrenoceptor beta 3 1.76864
CAPN10 calpain 10 1.63724
RETN resistin 1.60011
COG2 component of oligomeric golgi complex 2 1.58448
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 1.57467
HBA1 hemoglobin, alpha 1 1.52732
HBA2 hemoglobin, alpha 2 1.526
HNF1A HNF1 homeobox A 1.50184
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.49921
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.49701
APOA1 apolipoprotein A-I 1.47506
IGF1 insulin-like growth factor 1 (somatomedin C) 1.41008
NAMPT nicotinamide phosphoribosyltransferase 1.37163
LAD1 ladinin 1 1.36422
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 1.36248
LPL lipoprotein lipase 1.36248
RBP4 retinol binding protein 4, plasma 1.3603
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 1.35681
GHRL ghrelin/obestatin prepropeptide 1.35376
PPARA peroxisome proliferator-activated receptor alpha 1.3324
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 1.32978
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 1.32061
IRS2 insulin receptor substrate 2 1.3145
LPA lipoprotein, Lp(a) 1.29964
IL6 interleukin 6 1.29877
TCF7 transcription factor 7 (T-cell specific, HMG-box) 1.2595
PTPN1 protein tyrosine phosphatase, non-receptor type 1 1.25733
CETP cholesteryl ester transfer protein, plasma 1.23646
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 1.23473
TNF tumor necrosis factor 1.22345
SLC30A8 solute carrier family 30 (zinc transporter), member 8 1.22128
GCGR glucagon receptor 1.21565
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 1.18367
SOD2 superoxide dismutase 2, mitochondrial 1.16949
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.16093
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.16008
SST somatostatin 1.15922
SHBG sex hormone-binding globulin 1.15453
PYY peptide YY 1.1367
PON1 paraoxonase 1 1.11982
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 1.10973
FGF21 fibroblast growth factor 21 1.10594
FABP2 fatty acid binding protein 2, intestinal 1.10132
GPR119 G protein-coupled receptor 119 1.09881
LEPR leptin receptor 1.08873
FTO fat mass and obesity associated 1.08202
ZDHHC23 zinc finger, DHHC-type containing 23 1.05723
APOE apolipoprotein E 1.05513
HNF4A hepatocyte nuclear factor 4, alpha 1.05387
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.04504
CAT catalase 1.04293
PLG plasminogen 1.04209
NOS3 nitric oxide synthase 3 (endothelial cell) 1.03914
GPX1 glutathione peroxidase 1 1.03114
HHEX hematopoietically expressed homeobox 1.02608
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 1.0244
VCAM1 vascular cell adhesion molecule 1 1.02397
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.01807
APOC3 apolipoprotein C-III 1.01723
GPX5 glutathione peroxidase 5 1.0168
GPX4 glutathione peroxidase 4 1.01343
SELE selectin E 1.00372
BGLAP bone gamma-carboxyglutamate (gla) protein 0.990644
HK2 hexokinase 2 0.97086
PTPRN protein tyrosine phosphatase, receptor type, N 0.97086
VWF von Willebrand factor 0.97044
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.963728
ITLN1 intelectin 1 (galactofuranose binding) 0.961216
STK38 serine/threonine kinase 38 0.960378
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) 0.95369
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.951604
ICAM1 intercellular adhesion molecule 1 0.946186
ALLC allantoicase 0.940364
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 0.937044
FFAR1 free fatty acid receptor 1 0.911845
PLTP phospholipid transfer protein 0.909787
PDX1 pancreatic and duodenal homeobox 1 0.906086
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 0.897872
MGAM maltase-glucoamylase 0.893769
FOXM1 forkhead box M1 0.885979
CCL2 chemokine (C-C motif) ligand 2 0.88516
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.880243
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.878195
FOXO1 forkhead box O1 0.877786
HK1 hexokinase 1 0.876148
APOA2 apolipoprotein A-II 0.870415
IGFBP1 insulin-like growth factor binding protein 1 0.86714
IDE insulin-degrading enzyme 0.86059
MYDGF myeloid-derived growth factor 0.844211
F7 coagulation factor VII (serum prothrombin conversion accelerator) 0.833558
HNF1B HNF1 homeobox B 0.819206
GPR83 G protein-coupled receptor 83 0.817565
EDN1 endothelin 1 0.811821
SIRT1 sirtuin 1 0.804846
REN renin 0.803205
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 0.797052
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 0.792131
G6PC glucose-6-phosphatase, catalytic subunit 0.785574
PPY pancreatic polypeptide 0.784345
DNAH8 dynein, axonemal, heavy chain 8 0.782707
ALMS1 Alstrom syndrome protein 1 0.779841
PLAT plasminogen activator, tissue 0.776977
LIPE lipase, hormone-sensitive 0.771661
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 0.769618
GGT1 gamma-glutamyltransferase 1 0.74883
IGFBP3 insulin-like growth factor binding protein 3 0.744766
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 0.737054
PFKM phosphofructokinase, muscle 0.734622
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.732596
SREBF1 sterol regulatory element binding transcription factor 1 0.718443
ADIPOR1 adiponectin receptor 1 0.711989
CCK cholecystokinin 0.711587
TGM4 transglutaminase 4 0.708364
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.706351
SLC5A11 solute carrier family 5 (sodium/inositol cotransporter), member 11 0.70434
PCSK1 proprotein convertase subtilisin/kexin type 1 0.6939
PYGL phosphorylase, glycogen, liver 0.693098
CCKAR cholecystokinin A receptor 0.691896
CFD complement factor D (adipsin) 0.685491
PTH parathyroid hormone 0.681495
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.681096
PLIN1 perilipin 1 0.680697
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 0.677903
PYGB phosphorylase, glycogen; brain 0.67312
DLL1 delta-like 1 (Drosophila) 0.668742
HIRA histone cell cycle regulator 0.668345
GYS1 glycogen synthase 1 (muscle) 0.666358
FABP4 fatty acid binding protein 4, adipocyte 0.662784
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.660008
AHSG alpha-2-HS-glycoprotein 0.658818
B2M beta-2-microglobulin 0.658026
AGER advanced glycosylation end product-specific receptor 0.65763
VPREB1 pre-B lymphocyte 1 0.65565
PPP1R3A protein phosphatase 1, regulatory subunit 3A 0.643797
ETV3 ets variant 3 0.643404
PYGM phosphorylase, glycogen, muscle 0.642221
ADIPOR2 adiponectin receptor 2 0.642221
ACACB acetyl-CoA carboxylase beta 0.637102
LCAT lecithin-cholesterol acyltransferase 0.635921
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.634742
PPARD peroxisome proliferator-activated receptor delta 0.634742
THBD thrombomodulin 0.633563
MC4R melanocortin 4 receptor 0.629242
GCKR glucokinase (hexokinase 4) regulator 0.629242
NEUROD1 neuronal differentiation 1 0.627672
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 0.626888
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 0.620617
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.620226
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.613574
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 0.606152
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.60186
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.60108
ALPPL2 alkaline phosphatase, placental-like 2 0.6003
ALPP alkaline phosphatase, placental 0.59991
ALPL alkaline phosphatase, liver/bone/kidney 0.59952
USF1 upstream transcription factor 1 0.597181
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 0.597181
IL1B interleukin 1, beta 0.58939
APOA5 apolipoprotein A-V 0.583163
MTNR1B melatonin receptor 1B 0.58005
TXNL4B thioredoxin-like 4B 0.578883
PCSK2 proprotein convertase subtilisin/kexin type 2 0.575772
POMC proopiomelanocortin 0.566054
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.558285
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.554791
CST3 cystatin C 0.552075
PC pyruvate carboxylase 0.548583
NPPA natriuretic peptide A 0.547807
IL18 interleukin 18 0.547807
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 0.547032
LIPC lipase, hepatic 0.545093
FBP1 fructose-1,6-bisphosphatase 1 0.541605
SCARB1 scavenger receptor class B, member 1 0.533861
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.531541
CD36 CD36 molecule (thrombospondin receptor) 0.528063
MMP9 matrix metallopeptidase 9 0.526518
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.526132
F3 coagulation factor III (thromboplastin, tissue factor) 0.524202
TF transferrin 0.523816
GSR glutathione reductase 0.522273
FUS FUS RNA binding protein 0.520346
PTPRD protein tyrosine phosphatase, receptor type, D 0.519575
GAL galanin/GMAP prepropeptide 0.51919
FTH1 ferritin, heavy polypeptide 1 0.518805
SOST sclerostin 0.517265
CSRNP2 cysteine-serine-rich nuclear protein 2 0.514186
ARL8A ADP-ribosylation factor-like 8A 0.514186
TAS2R9 taste receptor, type 2, member 9 0.514186
TGFB1 transforming growth factor, beta 1 0.513417
SUMO4 small ubiquitin-like modifier 4 0.511112
APOC2 apolipoprotein C-II 0.508424
CD40LG CD40 ligand 0.50459
FTL ferritin, light polypeptide 0.503824
TLR4 toll-like receptor 4 0.503441
LYZL1 lysozyme-like 1 0.502675
GIPR gastric inhibitory polypeptide receptor 0.502292
FBXL20 F-box and leucine-rich repeat protein 20 0.500379
CALCA calcitonin-related polypeptide alpha 0.498085
GSTM1 glutathione S-transferase mu 1 0.493503
CS citrate synthase 0.491978
HMGA1 high mobility group AT-hook 1 0.487027
GC group-specific component (vitamin D binding protein) 0.483604
CACNB1 calcium channel, voltage-dependent, beta 1 subunit 0.476393
KNG1 kininogen 1 0.472604
PON2 paraoxonase 2 0.470711
STAP2 signal transducing adaptor family member 2 0.469954
WFS1 Wolfram syndrome 1 (wolframin) 0.469197
ACP1 acid phosphatase 1, soluble 0.467306
FADS2 fatty acid desaturase 2 0.463905
NPY neuropeptide Y 0.458619
SLC5A4 solute carrier family 5 (glucose activated ion channel), member 4 0.455978
CPB2 carboxypeptidase B2 (plasma) 0.453339
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 0.451078
AGTR1 angiotensin II receptor, type 1 0.449947
APOA4 apolipoprotein A-IV 0.448064
UTS2 urotensin 2 0.446558
PKM pyruvate kinase, muscle 0.444676
TRIB3 tribbles pseudokinase 3 0.443547
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 0.44129
F2 coagulation factor II (thrombin) 0.43941
GANC glucosidase, alpha; neutral C 0.439034
NR1H4 nuclear receptor subfamily 1, group H, member 4 0.437906
FADS1 fatty acid desaturase 1 0.437154
FADS3 fatty acid desaturase 3 0.435275
SCARB2 scavenger receptor class B, member 2 0.433772
HP haptoglobin 0.433772
PKLR pyruvate kinase, liver and RBC 0.433021
G6PD glucose-6-phosphate dehydrogenase 0.431519
CP ceruloplasmin (ferroxidase) 0.431144
HPR haptoglobin-related protein 0.427765
GSTTP1 glutathione S-transferase theta pseudogene 1 0.427015
GSTT1 glutathione S-transferase theta 1 0.427015
ARL15 ADP-ribosylation factor-like 15 0.427015
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.422515
GSTA4 glutathione S-transferase alpha 4 0.421016
KCND1 potassium channel, voltage gated Shal related subfamily D, member 1 0.419892
SCN2A sodium channel, voltage gated, type II alpha subunit 0.416896
SOCS3 suppressor of cytokine signaling 3 0.41465
BDNF brain-derived neurotrophic factor 0.41465
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 0.413527
MTTP microsomal triglyceride transfer protein 0.413527
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.413527
AOC2 amine oxidase, copper containing 2 (retina-specific) 0.412031
LPIN1 lipin 1 0.410909
HLA-C major histocompatibility complex, class I, C 0.410909
HMX1 H6 family homeobox 1 0.409787
SLC30A10 solute carrier family 30, member 10 0.407919
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 0.406798
GSTA3 glutathione S-transferase alpha 3 0.402318
CCDC63 coiled-coil domain containing 63 0.401945
GSTA2 glutathione S-transferase alpha 2 0.401199
MUL1 mitochondrial E3 ubiquitin protein ligase 1 0.400453
PNLIP pancreatic lipase 0.399707
RRAD Ras-related associated with diabetes 0.398589
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.396725
GSTA1 glutathione S-transferase alpha 1 0.394118
SORBS1 sorbin and SH3 domain containing 1 0.394118
SNAPIN SNAP-associated protein 0.393001
USP36 ubiquitin specific peptidase 36 0.390025
ADA adenosine deaminase 0.388166
ADIPOQ adiponectin, C1Q and collagen domain containing 0.386679
NCKAP5L NCK-associated protein 5-like 0.385193
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.383337
ERI1 exoribonuclease 1 0.381852
GYG1 glycogenin 1 0.379997
IGF2 insulin-like growth factor 2 0.371477
PEA15 phosphoprotein enriched in astrocytes 15 0.36741
MLX MLX, MAX dimerization protein 0.365193
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 0.360764
TXNIP thioredoxin interacting protein 0.359289
ZNF208 zinc finger protein 208 0.355972
UTS2R urotensin 2 receptor 0.355235
AMY2A amylase, alpha 2A (pancreatic) 0.354499
ELMO1 engulfment and cell motility 1 0.353763
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.351187
PRKAG3 protein kinase, AMP-activated, gamma 3 non-catalytic subunit 0.350452
CAPN5 calpain 5 0.346409
ISL1 ISL LIM homeobox 1 0.345308
ESYT2 extended synaptotagmin-like protein 2 0.343106
IL1RN interleukin 1 receptor antagonist 0.343106
CPE carboxypeptidase E 0.342006
LPIN3 lipin 3 0.335046
NPS neuropeptide S 0.335046
PLIN4 perilipin 4 0.334315
CHN2 chimerin 2 0.333218
PNPLA2 patatin-like phospholipase domain containing 2 0.330295
IGLL5 immunoglobulin lambda-like polypeptide 5 0.330295
DGAT1 diacylglycerol O-acyltransferase 1 0.328105
CXCL10 chemokine (C-X-C motif) ligand 10 0.327375
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.325916
HMOX1 heme oxygenase 1 0.325187
IL10 interleukin 10 0.322637
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12 0.321545
GPBAR1 G protein-coupled bile acid receptor 1 0.317545
FN1 fibronectin 1 0.311377
DLK1 delta-like 1 homolog (Drosophila) 0.309928
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 0.308118
CORT cortistatin 0.305948
TLL1 tolloid-like 1 0.305587
ADRA2B adrenoceptor alpha 2B 0.304864
LEPROT leptin receptor overlapping transcript 0.304142
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 0.303781
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 0.302698
KCTD15 potassium channel tetramerization domain containing 15 0.302337
MMP2 matrix metallopeptidase 2 0.300894
OR10A4 olfactory receptor, family 10, subfamily A, member 4 0.300173
NRF1 nuclear respiratory factor 1 0.299452
PNPLA3 patatin-like phospholipase domain containing 3 0.298011
PRDX4 peroxiredoxin 4 0.297651
GGT2 gamma-glutamyltransferase 2 0.297291
DMBX1 diencephalon/mesencephalon homeobox 1 0.292975
PCYOX1L prenylcysteine oxidase 1 like 0.288668
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.288668
HFE hemochromatosis 0.287952
TRO trophinin 0.287593
TPO thyroid peroxidase 0.284013
SLC27A1 solute carrier family 27 (fatty acid transporter), member 1 0.283655
CD79A CD79a molecule, immunoglobulin-associated alpha 0.283655
FFAR4 free fatty acid receptor 4 0.28294
DPP8 dipeptidyl-peptidase 8 0.282582
BCHE butyrylcholinesterase 0.28151
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1 0.281153
VASP vasodilator-stimulated phosphoprotein 0.281153
STARD4 StAR-related lipid transfer (START) domain containing 4 0.275089
PGF placental growth factor 0.274732
TRPC1 transient receptor potential cation channel, subfamily C, member 1 0.273308
CPT2 carnitine palmitoyltransferase 2 0.273308
PDE3B phosphodiesterase 3B, cGMP-inhibited 0.266913
GHR growth hormone receptor 0.265849
SORCS1 sortilin-related VPS10 domain containing receptor 1 0.265494
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 0.265494
ASCL3 achaete-scute family bHLH transcription factor 3 0.26514
JUN jun proto-oncogene 0.264785
HACD2 3-hydroxyacyl-CoA dehydratase 2 0.262306
ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative) 0.262306
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 0.261952
PRRC2A proline-rich coiled-coil 2A 0.260891
FLNA filamin A, alpha 0.260538
HSD17B13 hydroxysteroid (17-beta) dehydrogenase 13 0.259124
NEIL3 nei endonuclease VIII-like 3 (E. coli) 0.25877
FGD1 FYVE, RhoGEF and PH domain containing 1 0.257711
ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit 0.256299
KCNA7 potassium channel, voltage gated shaker related subfamily A, member 7 0.255946
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 0.253127
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.252774
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.251366
LGTN ligatin 0.251015
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) 0.248554
MYL1 myosin, light chain 1, alkali; skeletal, fast 0.248554
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 0.248203
GANAB glucosidase, alpha; neutral AB 0.248203
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.246799
NFIA nuclear factor I/A 0.246098
PLIN5 perilipin 5 0.243995
MAPK8 mitogen-activated protein kinase 8 0.243645
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 0.241546
PER1 period circadian clock 1 0.240497
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.240148
MPO myeloperoxidase 0.238752
ANGPTL4 angiopoietin-like 4 0.238403
GPR142 G protein-coupled receptor 142 0.238054
ACOT7 acyl-CoA thioesterase 7 0.237706
ADRB2 adrenoceptor beta 2, surface 0.235964
GNPDA2 glucosamine-6-phosphate deaminase 2 0.235964
ACE2 angiotensin I converting enzyme 2 0.235268
NFIB nuclear factor I/B 0.23353
ELMO2 engulfment and cell motility 2 0.232489
VIMP VCP-interacting membrane selenoprotein 0.231102
CREM cAMP responsive element modulator 0.231102
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit 0.230755
PTS 6-pyruvoyltetrahydropterin synthase 0.230755
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 0.230755
SDC2 syndecan 2 0.230409
TOMM5 translocase of outer mitochondrial membrane 5 homolog (yeast) 0.227297
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 0.227297
SUDS3 suppressor of defective silencing 3 homolog (S. cerevisiae) 0.222136
ATF6 activating transcription factor 6 0.221108
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6 0.219398
CYBA cytochrome b-245, alpha polypeptide 0.219398
HRC histidine rich calcium binding protein 0.218034
CHD9 chromodomain helicase DNA binding protein 9 0.217012
SULF2 sulfatase 2 0.216332
OMA1 OMA1 zinc metallopeptidase 0.215992
FASN fatty acid synthase 0.215992
CD4 CD4 molecule 0.211934
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 0.211261
RNF24 ring finger protein 24 0.210253
NUCB1 nucleobindin 1 0.209583
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.208914
VEGFA vascular endothelial growth factor A 0.207578
PLA2G1B phospholipase A2, group IB (pancreas) 0.206913
PAX4 paired box 4 0.205916
IGF1R insulin-like growth factor 1 receptor 0.205585
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 0.205585
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 0.205254
LMX1A LIM homeobox transcription factor 1, alpha 0.203933
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.202946
NUCB2 nucleobindin 2 0.20229
DSE dermatan sulfate epimerase 0.201308
ACPP acid phosphatase, prostate 0.199356
MYNN myoneurin 0.199033
MN1 meningioma (disrupted in balanced translocation) 1 0.198709
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2 0.194548
GRB14 growth factor receptor-bound protein 14 0.1936
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.192657
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 0.190786
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 0.189551
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.189551
HRAS Harvey rat sarcoma viral oncogene homolog 0.188938
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 0.188938
NR1H3 nuclear receptor subfamily 1, group H, member 3 0.187719
ADCY2 adenylate cyclase 2 (brain) 0.185612
CLCN6 chloride channel, voltage-sensitive 6 0.185612
PSRC1 proline/serine-rich coiled-coil 1 0.182086
SPTLC3 serine palmitoyltransferase, long chain base subunit 3 0.182086
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.181798
PER2 period circadian clock 2 0.181798
IGLV2-8 immunoglobulin lambda variable 2-8 0.18151
C1QTNF1 C1q and tumor necrosis factor related protein 1 0.18151
FOXP2 forkhead box P2 0.181222
FOXJ2 forkhead box J2 0.180937
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 0.180937
ALPK3 alpha-kinase 3 0.179802
DPP9 dipeptidyl-peptidase 9 0.179239
PRAP1 proline-rich acidic protein 1 0.17896
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 0.17896
SIM2 single-minded family bHLH transcription factor 2 0.177301
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 0.177029
CDK5 cyclin-dependent kinase 5 0.175947
ATP10D ATPase, class V, type 10D 0.175679
ILVBL ilvB (bacterial acetolactate synthase)-like 0.175411
BDH1 3-hydroxybutyrate dehydrogenase, type 1 0.175146
CD34 CD34 molecule 0.175146
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1 0.171286
GYS2 glycogen synthase 2 (liver) 0.171036
SPP1 secreted phosphoprotein 1 0.166319
GSTP1 glutathione S-transferase pi 1 0.166095
SIRT2 sirtuin 2 0.165655
ANGPT2 angiopoietin 2 0.164571
CAMK4 calcium/calmodulin-dependent protein kinase IV 0.163938
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.163523
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 0.162908
NR3C2 nuclear receptor subfamily 3, group C, member 2 0.162109
IGLV3-10 immunoglobulin lambda variable 3-10 0.161716
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 0.161716
ACTB actin, beta 0.161331
PLN phospholamban 0.161139
SELENBP1 selenium binding protein 1 0.160203
NKAIN2 Na+/K+ transporting ATPase interacting 2 0.159838
CACNB3 calcium channel, voltage-dependent, beta 3 subunit 0.158605
IGLV3-21 immunoglobulin lambda variable 3-21 0.158605
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B 0.157929
GH1 growth hormone 1 0.157765
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 0.157765
PTRF polymerase I and transcript release factor 0.148572
RNLS renalase, FAD-dependent amine oxidase 0.144764
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 0.144187
ASRGL1 asparaginase like 1 0.144179
KIF5C kinesin family member 5C 0.143853
FOXO4 forkhead box O4 0.143428
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4 0.143417
PPP6R2 protein phosphatase 6, regulatory subunit 2 0.142993
BAG4 BCL2-associated athanogene 4 0.142121
OXCT1 3-oxoacid CoA transferase 1 0.142109
MB myoglobin 0.141559
GPIHBP1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 0.141133
FFAR2 free fatty acid receptor 2 0.141063
AVP arginine vasopressin 0.140984
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.140584
SLC35E2B solute carrier family 35, member E2B 0.140479
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 0.140434
ZBTB17 zinc finger and BTB domain containing 17 0.140425
AADAT aminoadipate aminotransferase 0.140003
HLA-DQB3 major histocompatibility complex, class II, DQ beta 3 0.139661
PTP4A1 protein tyrosine phosphatase type IVA, member 1 0.13947
PIDD1 p53-induced death domain protein 1 0.139438
SLC43A2 solute carrier family 43 (amino acid system L transporter), member 2 0.139438
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 0.139427
CCBL1 cysteine conjugate-beta lyase, cytoplasmic 0.139149
FXN frataxin 0.139138
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria 0.138737
NPB neuropeptide B 0.138069
C3 complement component 3 0.137549
TNNI3 troponin I type 3 (cardiac) 0.137341
POMP proteasome maturation protein 0.137296
CCR2 chemokine (C-C motif) receptor 2 0.136514
CAV1 caveolin 1, caveolae protein, 22kDa 0.136395
KIF5A kinesin family member 5A 0.136135
ACAT1 acetyl-CoA acetyltransferase 1 0.135791
MMAA methylmalonic aciduria (cobalamin deficiency) cblA type 0.135755
SLC22A12 solute carrier family 22 (organic anion/urate transporter), member 12 0.135567
HCAR2 hydroxycarboxylic acid receptor 2 0.135567
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 0.135567
DYNLRB1 dynein, light chain, roadblock-type 1 0.135297
KCNK2 potassium channel, two pore domain subfamily K, member 2 0.135078