type 2 diabetes; reduced prostate cancer risk Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description disease cluster belonging to disease group metabolic (Genetic Association Database)
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Genes

33 genes associated with the disease type 2 diabetes; reduced prostate cancer risk in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
C1QTNF6 C1q and tumor necrosis factor related protein 6
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CLEC16A C-type lectin domain family 16, member A
CTSH cathepsin H
ERBB3 erb-b2 receptor tyrosine kinase 3
FTO fat mass and obesity associated
HHEX hematopoietically expressed homeobox
HNF1B HNF1 homeobox B
IDE insulin-degrading enzyme
IFIH1 interferon induced with helicase C domain 1
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IL2 interleukin 2
IL21 interleukin 21
IL2RA interleukin 2 receptor, alpha
INS insulin
JAZF1 JAZF zinc finger 1
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit
NOTCH2 notch 2
PPARG peroxisome proliferator-activated receptor gamma
PRKCQ protein kinase C, theta
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
SLC30A8 solute carrier family 30 (zinc transporter), member 8
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
THADA thyroid adenoma associated
TSPAN8 tetraspanin 8
WFS1 Wolfram syndrome 1 (wolframin)