type 1 diabetes Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description disease cluster belonging to disease group immune (Genetic Association Database)
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Genes

50 genes associated with the disease type 1 diabetes in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
AFF3 AF4/FMR2 family, member 3
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
C1QTNF6 C1q and tumor necrosis factor related protein 6
CAPSL calcyphosine-like
CD226 CD226 molecule
CD69 CD69 molecule
CDK2 cyclin-dependent kinase 2
CENPW centromere protein W
CLEC16A C-type lectin domain family 16, member A
COBL cordon-bleu WH2 repeat protein
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSH cathepsin H
DIO3 deiodinase, iodothyronine, type III
DLK1 delta-like 1 homolog (Drosophila)
ERBB3 erb-b2 receptor tyrosine kinase 3
GLIS3 GLIS family zinc finger 3
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-E major histocompatibility complex, class I, E
IFIH1 interferon induced with helicase C domain 1
IKZF4 IKAROS family zinc finger 4 (Eos)
IL10 interleukin 10
IL2 interleukin 2
IL27 interleukin 27
IL2RA interleukin 2 receptor, alpha
IL7R interleukin 7 receptor
INS insulin
LPAR3 lysophosphatidic acid receptor 3
MEG3 maternally expressed 3 (non-protein coding)
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3
PGM1 phosphoglucomutase 1
PHTF1 putative homeodomain transcription factor 1
PRKCQ protein kinase C, theta
PRM3 protamine 3
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RAB5B RAB5B, member RAS oncogene family
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RMI2 RecQ mediated genome instability 2
RNLS renalase, FAD-dependent amine oxidase
RTL1 retrotransposon-like 1
SH2B3 SH2B adaptor protein 3
SUOX sulfite oxidase
TNP2 transition protein 2 (during histone to protamine replacement)
TRAFD1 TRAF-type zinc finger domain containing 1
TYK2 tyrosine kinase 2
UBASH3A ubiquitin associated and SH3 domain containing A