tyloxapol-4611 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools


196 genes differentially expressed following the tyloxapol-4611 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABHD6 abhydrolase domain containing 6
APOL1 apolipoprotein L, 1
BEX1 brain expressed, X-linked 1
C1QL1 complement component 1, q subcomponent-like 1
C22ORF24 chromosome 22 open reading frame 24
C5AR2 complement component 5a receptor 2
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CD1C CD1c molecule
CD4 CD4 molecule
CDRT1 CMT1A duplicated region transcript 1
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CEMP1 cementum protein 1
CLTCL1 clathrin, heavy chain-like 1
COL14A1 collagen, type XIV, alpha 1
COL1A1 collagen, type I, alpha 1
CPED1 cadherin-like and PC-esterase domain containing 1
CRH corticotropin releasing hormone
DICER1 dicer 1, ribonuclease type III
DUX4L8 double homeobox 4 like 8
E2F4 E2F transcription factor 4, p107/p130-binding
EPB41L1 erythrocyte membrane protein band 4.1-like 1
EPS8L1 EPS8-like 1
FABP3 fatty acid binding protein 3, muscle and heart
FAM134B family with sequence similarity 134, member B
FAM182A family with sequence similarity 182, member A
FFAR2 free fatty acid receptor 2
FGF4 fibroblast growth factor 4
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GDF10 growth differentiation factor 10
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
GPM6A glycoprotein M6A
GPM6B glycoprotein M6B
GPX7 glutathione peroxidase 7
GREB1L growth regulation by estrogen in breast cancer-like
HES2 hes family bHLH transcription factor 2
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
IAPP islet amyloid polypeptide
ICA1 islet cell autoantigen 1, 69kDa
IGHM immunoglobulin heavy constant mu
IL37 interleukin 37
ITGB4 integrin, beta 4
JAM2 junctional adhesion molecule 2
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KIAA0509 uncharacterized LOC57242
LOXL3 lysyl oxidase-like 3
LTC4S leukotriene C4 synthase
MAP2K7 mitogen-activated protein kinase kinase 7
MFAP3L microfibrillar-associated protein 3-like
MFAP5 microfibrillar associated protein 5
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NEK11 NIMA-related kinase 11
NF1 neurofibromin 1
NRF1 nuclear respiratory factor 1
NRG1 neuregulin 1
PAEP progestagen-associated endometrial protein
PARP8 poly (ADP-ribose) polymerase family, member 8
PDE10A phosphodiesterase 10A
PDE4A phosphodiesterase 4A, cAMP-specific
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PML promyelocytic leukemia
POM121 POM121 transmembrane nucleoporin
PPEF1 protein phosphatase, EF-hand calcium binding domain 1
PTPN12 protein tyrosine phosphatase, non-receptor type 12
REC8 REC8 meiotic recombination protein
RGS14 regulator of G-protein signaling 14
RPH3A rabphilin 3A
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SEPP1 selenoprotein P, plasma, 1
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SGK2 serum/glucocorticoid regulated kinase 2
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
SLC22A2 solute carrier family 22 (organic cation transporter), member 2
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SMAD6 SMAD family member 6
SOS2 son of sevenless homolog 2 (Drosophila)
ST14 suppression of tumorigenicity 14 (colon carcinoma)
SULF1 sulfatase 1
TET3 tet methylcytosine dioxygenase 3
THEMIS2 thymocyte selection associated family member 2
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TSGA10 testis specific, 10
TTC30A tetratricopeptide repeat domain 30A
TTLL5 tubulin tyrosine ligase-like family member 5
VEZT vezatin, adherens junctions transmembrane protein
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae)
VTCN1 V-set domain containing T cell activation inhibitor 1
ZBTB20 zinc finger and BTB domain containing 20
ZCCHC14 zinc finger, CCHC domain containing 14
ZNF467 zinc finger protein 467
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ADGRB2 adhesion G protein-coupled receptor B2
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALPK1 alpha-kinase 1
ANKFY1 ankyrin repeat and FYVE domain containing 1
APH1B APH1B gamma secretase subunit
ARRB2 arrestin, beta 2
BAG4 BCL2-associated athanogene 4
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C17ORF70 chromosome 17 open reading frame 70
C1ORF159 chromosome 1 open reading frame 159
CA5BP1 carbonic anhydrase VB pseudogene 1
CA9 carbonic anhydrase IX
CEP131 centrosomal protein 131kDa
CINP cyclin-dependent kinase 2 interacting protein
CLDN15 claudin 15
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DTX2 deltex 2, E3 ubiquitin ligase
ECE1 endothelin converting enzyme 1
ERAP2 endoplasmic reticulum aminopeptidase 2
ETNK2 ethanolamine kinase 2
ETV4 ets variant 4
FAT4 FAT atypical cadherin 4
FRMPD1 FERM and PDZ domain containing 1
GJC1 gap junction protein, gamma 1, 45kDa
GLS2 glutaminase 2 (liver, mitochondrial)
GPALPP1 GPALPP motifs containing 1
GPR176 G protein-coupled receptor 176
GPR3 G protein-coupled receptor 3
HELZ helicase with zinc finger
HIST1H3A histone cluster 1, H3a
HIST1H3I histone cluster 1, H3i
IL15RA interleukin 15 receptor, alpha
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KDM8 lysine (K)-specific demethylase 8
KIAA0753 KIAA0753
KLF13 Kruppel-like factor 13
KRT8P12 keratin 8 pseudogene 12
MBTD1 mbt domain containing 1
MFSD12 major facilitator superfamily domain containing 12
MOGS mannosyl-oligosaccharide glucosidase
MX1 MX dynamin-like GTPase 1
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NPPB natriuretic peptide B
NT5DC3 5'-nucleotidase domain containing 3
OLFM4 olfactomedin 4
OR1G1 olfactory receptor, family 1, subfamily G, member 1
OSBP2 oxysterol binding protein 2
OSMR oncostatin M receptor
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PALM paralemmin
PCOLCE procollagen C-endopeptidase enhancer
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PODXL2 podocalyxin-like 2
PTDSS2 phosphatidylserine synthase 2
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTK6 protein tyrosine kinase 6
RBL1 retinoblastoma-like 1
RIMBP2 RIMS binding protein 2
RNF31 ring finger protein 31
RRAGB Ras-related GTP binding B
RWDD2A RWD domain containing 2A
SCN1B sodium channel, voltage gated, type I beta subunit
SEC14L2 SEC14-like 2 (S. cerevisiae)
SFRP5 secreted frizzled-related protein 5
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SNTA1 syntrophin, alpha 1
SOX30 SRY (sex determining region Y)-box 30
STK16 serine/threonine kinase 16
STXBP2 syntaxin binding protein 2
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TCTN1 tectonic family member 1
TFIP11 tuftelin interacting protein 11
THBS3 thrombospondin 3
TMEM212 transmembrane protein 212
TRIM45 tripartite motif containing 45
TSPAN2 tetraspanin 2
TUBA3D tubulin, alpha 3d
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR25 WD repeat domain 25
WDR76 WD repeat domain 76
ZMAT5 zinc finger, matrin-type 5
ZNF227 zinc finger protein 227
ZNF37BP zinc finger protein 37B, pseudogene
ZNF385D zinc finger protein 385D
ZNF415 zinc finger protein 415
ZNF606 zinc finger protein 606