tumorigenicity Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

227 genes co-occuring with the biological term tumorigenicity in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACTN4 actinin, alpha 4
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
AGK acylglycerol kinase
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALK anaplastic lymphoma receptor tyrosine kinase
AMIGO2 adhesion molecule with Ig-like domain 2
ASCL1 achaete-scute family bHLH transcription factor 1
AURKA aurora kinase A
AXL AXL receptor tyrosine kinase
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
BCL2 B-cell CLL/lymphoma 2
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BIRC5 baculoviral IAP repeat containing 5
BIRC7 baculoviral IAP repeat containing 7
BMP7 bone morphogenetic protein 7
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA2 breast cancer 2, early onset
BRD7 bromodomain containing 7
BRMS1 breast cancer metastasis suppressor 1
BSG basigin (Ok blood group)
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CASP14 caspase 14, apoptosis-related cysteine peptidase
CASZ1 castor zinc finger 1
CAV1 caveolin 1, caveolae protein, 22kDa
CBX1 chromobox homolog 1
CBX5 chromobox homolog 5
CCND2 cyclin D2
CCNE1 cyclin E1
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK4 cyclin-dependent kinase 4
CDK6 cyclin-dependent kinase 6
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
CPE carboxypeptidase E
CREBBP CREB binding protein
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CSF3R colony stimulating factor 3 receptor (granulocyte)
CTGF connective tissue growth factor
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CYR61 cysteine-rich, angiogenic inducer, 61
DKK1 dickkopf WNT signaling pathway inhibitor 1
DKK2 dickkopf WNT signaling pathway inhibitor 2
DLC1 DLC1 Rho GTPase activating protein
DLK1 delta-like 1 homolog (Drosophila)
DUSP6 dual specificity phosphatase 6
E2F1 E2F transcription factor 1
E2F2 E2F transcription factor 2
EGFR epidermal growth factor receptor
ELP5 elongator acetyltransferase complex subunit 5
ELP6 elongator acetyltransferase complex subunit 6
EPAS1 endothelial PAS domain protein 1
EPCAM epithelial cell adhesion molecule
EPHA2 EPH receptor A2
ERBB2 erb-b2 receptor tyrosine kinase 2
ERGIC2 ERGIC and golgi 2
EWSR1 EWS RNA-binding protein 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
EZR ezrin
FAM83B family with sequence similarity 83, member B
FEZF1 FEZ family zinc finger 1
FGF2 fibroblast growth factor 2 (basic)
FGFR2 fibroblast growth factor receptor 2
FHIT fragile histidine triad
FHL2 four and a half LIM domains 2
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXM1 forkhead box M1
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FPR2 formyl peptide receptor 2
GLI3 GLI family zinc finger 3
GSK3B glycogen synthase kinase 3 beta
GSN gelsolin
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
HAS2 hyaluronan synthase 2
HAX1 HCLS1 associated protein X-1
HDAC3 histone deacetylase 3
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMGA1 high mobility group AT-hook 1
HMOX1 heme oxygenase 1
HOXB7 homeobox B7
HOXB9 homeobox B9
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
ICAM1 intercellular adhesion molecule 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IFITM1 interferon induced transmembrane protein 1
IFNG interferon, gamma
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGF2R insulin-like growth factor 2 receptor
IGFBP1 insulin-like growth factor binding protein 1
IGFBP5 insulin-like growth factor binding protein 5
IGFBP7 insulin-like growth factor binding protein 7
IL17B interleukin 17B
IL17RB interleukin 17 receptor B
IL33 interleukin 33
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA6 integrin, alpha 6
KDM1A lysine (K)-specific demethylase 1A
KDM2A lysine (K)-specific demethylase 2A
KDR kinase insert domain receptor
KIF5B kinesin family member 5B
KLF6 Kruppel-like factor 6
KLF9 Kruppel-like factor 9
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KRAS Kirsten rat sarcoma viral oncogene homolog
LAMA4 laminin, alpha 4
LAMB2 laminin, beta 2 (laminin S)
LDHA lactate dehydrogenase A
LIN28A lin-28 homolog A (C. elegans)
MAGEC2 melanoma antigen family C2
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MATK megakaryocyte-associated tyrosine kinase
MCTS1 malignant T cell amplified sequence 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED23 mediator complex subunit 23
MEF2D myocyte enhancer factor 2D
MET MET proto-oncogene, receptor tyrosine kinase
MGMT O-6-methylguanine-DNA methyltransferase
MIR134 microRNA 134
MIR138-1 microRNA 138-1
MIR145 microRNA 145
MIR152 microRNA 152
MIR17 microRNA 17
MIR31 microRNA 31
MIR335 microRNA 335
MIR363 microRNA 363
MIR374A microRNA 374a
MIR548B microRNA 548b
MKI67 marker of proliferation Ki-67
MMP1 matrix metallopeptidase 1
MMP11 matrix metallopeptidase 11
MTAP methylthioadenosine phosphorylase
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC1 mucin 1, cell surface associated
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NEFH neurofilament, heavy polypeptide
NEK7 NIMA-related kinase 7
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NME2 NME/NM23 nucleoside diphosphate kinase 2
NOS2 nitric oxide synthase 2, inducible
NOTCH1 notch 1
NRP1 neuropilin 1
OLFM4 olfactomedin 4
OPTN optineurin
PA2G4 proliferation-associated 2G4, 38kDa
PDGFD platelet derived growth factor D
PELP1 proline, glutamate and leucine rich protein 1
PFN1 profilin 1
PHF8 PHD finger protein 8
PHLDA2 pleckstrin homology-like domain, family A, member 2
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1
PLK1 polo-like kinase 1
POU5F1 POU class 5 homeobox 1
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PRKCI protein kinase C, iota
PRMT5 protein arginine methyltransferase 5
PROM1 prominin 1
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK6 protein tyrosine kinase 6
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTTG1 pituitary tumor-transforming 1
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RALB v-ral simian leukemia viral oncogene homolog B
RARB retinoic acid receptor, beta
RB1 retinoblastoma 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REST RE1-silencing transcription factor
RET ret proto-oncogene
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
RUNX2 runt-related transcription factor 2
RUVBL2 RuvB-like AAA ATPase 2
S100A4 S100 calcium binding protein A4
SAPCD2 suppressor APC domain containing 2
SFN stratifin
SFRP1 secreted frizzled-related protein 1
SFRP5 secreted frizzled-related protein 5
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIAH1 siah E3 ubiquitin protein ligase 1
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SMAD7 SMAD family member 7
SON SON DNA binding protein
SOX2 SRY (sex determining region Y)-box 2
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STIM1 stromal interaction molecule 1
STK26 serine/threonine protein kinase 26
STK31 serine/threonine kinase 31
STMN1 stathmin 1
SULF1 sulfatase 1
SYT13 synaptotagmin XIII
TERT telomerase reverse transcriptase
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFDP3 transcription factor Dp family, member 3
TGFB1 transforming growth factor, beta 1
TP53 tumor protein p53
TP63 tumor protein p63
TPD52 tumor protein D52
TRAF2 TNF receptor-associated factor 2
TRIM35 tripartite motif containing 35
TRIO trio Rho guanine nucleotide exchange factor
TTF1 transcription termination factor, RNA polymerase I
UVRAG UV radiation resistance associated
VEGFA vascular endothelial growth factor A
VEZT vezatin, adherens junctions transmembrane protein
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VIP vasoactive intestinal peptide
WWOX WW domain containing oxidoreductase
WWP2 WW domain containing E3 ubiquitin protein ligase 2
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
ZFX zinc finger protein, X-linked
ZNF521 zinc finger protein 521